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View Structure Prediction Details

Protein: UBX7
Organism: Saccharomyces cerevisiae
Length: 436 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBX7.

Description E-value Query
Range
Subject
Range
UBX7_YEAST - UBX domain-containing protein 7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UBX7 PE=...
UBX7 - UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p
0.0 [1..427] [1..427]
ubxn-4 - status:Confirmed UniProt:P34631 protein_id:AAA28196.1
6.0E-57 [78..424] [150..465]
PUX10_ARATH - Plant UBX domain-containing protein 10 OS=Arabidopsis thaliana GN=PUX10 PE=2 SV=1
3.0E-52 [2..292] [183..479]
Faf-PA, FBpp0309814 - The gene Fas-associated factor is referred to in FlyBase by the symbol Dmel\Faf (CG10372, FBgn002560...
gi|220955346, gi... - gi|220955346|gb|ACL90216.1| Faf-PA [synthetic construct], gi|220945460|gb|ACL85273.1| Faf-PA [synthe...
8.0E-45 [5..295] [163..464]
gi|215678662, gi... - gi|37536146|ref|NP_922375.1| unknown protein [Oryza sativa (japonica cultivar-group)], gi|31433109|g...
4.0E-44 [9..292] [174..464]
gi|3882309 - gi|3882309|dbj|BAA34514.1| KIAA0794 protein [Homo sapiens]
6.0E-41 [2..293] [147..489]

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Predicted Domain #1
Region A:
Residues: [1-78]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLEALFRDSV EEAINDSIKE GVVLAVYNTA RDDQWLKSWF KGDDVSLDTL AEHSIWLRLV  60
   61 KDTEQFQLFE QVFPNVVV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
protein disulfide isomerase activity 2.05206748531532 bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds 2.05206748531532 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups 1.83987272812734 bayes_pls_golite062009
intramolecular oxidoreductase activity 1.5535855642475 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
binding 0.665189138843282 bayes_pls_golite062009
protein binding 0.157273259994554 bayes_pls_golite062009
hydrolase activity 0.150237022038507 bayes_pls_golite062009
transcription regulator activity 0.13699526678272 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [79-194]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSIYLIRAGK IELIIQGEDD RHWEKLLACI GIKDKKAGES SSRETNPGLA REEKSSRDVH  60
   61 RKNARERIAE TTLEIQRREQ LKQRKLAEEE RERIIRLVRA DRAERKALDE THHRTL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.710 0.031 endoplasmic reticulum a.25.1 Ferritin-like
View Download 0.516 0.004 endoplasmic reticulum a.47.2 t-snare proteins
View Download 0.567 0.004 endoplasmic reticulum d.67.3 Ribosome recycling factor, RRF
View Download 0.554 0.002 endoplasmic reticulum f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.492 0.001 endoplasmic reticulum a.46.1 Methionine synthase domain
View Download 0.474 N/A N/A a.71.2 Helical domain of Sec23/24
View Download 0.472 N/A N/A f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.457 N/A N/A a.7.1 Spectrin repeat
View Download 0.451 N/A N/A a.7.1 Spectrin repeat
View Download 0.450 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.436 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.427 N/A N/A a.47.2 t-snare proteins
View Download 0.420 N/A N/A f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.411 N/A N/A f.18.1 F1F0 ATP synthase subunit A
View Download 0.411 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.410 N/A N/A a.7.1 Spectrin repeat
View Download 0.394 N/A N/A d.67.3 Ribosome recycling factor, RRF
View Download 0.381 N/A N/A a.29.4 RecG, N-terminal domain
View Download 0.376 N/A N/A a.7.1 Spectrin repeat
View Download 0.372 N/A N/A a.46.1 Methionine synthase domain
View Download 0.370 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.369 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.368 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.365 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.361 N/A N/A a.24.1 Apolipoprotein
View Download 0.361 N/A N/A a.24.1 Apolipoprotein
View Download 0.361 N/A N/A a.24.1 Apolipoprotein
View Download 0.351 N/A N/A a.24.3 Cytochromes
View Download 0.345 N/A N/A d.15.1 Ubiquitin-like
View Download 0.344 N/A N/A d.67.3 Ribosome recycling factor, RRF
View Download 0.342 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.338 N/A N/A f.17.2 Cytochrome c oxidase subunit II-like, transmembrane region
View Download 0.329 N/A N/A a.7.1 Spectrin repeat
View Download 0.327 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.322 N/A N/A d.129.4 Cell-division protein ZipA, C-terminal domain
View Download 0.321 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.314 N/A N/A a.63.1 Apolipophorin-III
View Download 0.314 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.305 N/A N/A a.130.1 Chorismate mutase II
View Download 0.304 N/A N/A d.67.3 Ribosome recycling factor, RRF
View Download 0.303 N/A N/A f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.301 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.297 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.295 N/A N/A a.7.1 Spectrin repeat
View Download 0.284 N/A N/A a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.275 N/A N/A b.84.2 Rudiment single hybrid motif
View Download 0.274 N/A N/A d.80.1 Tautomerase/MIF
View Download 0.269 N/A N/A a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.267 N/A N/A a.7.1 Spectrin repeat
View Download 0.265 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.264 N/A N/A d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.264 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.262 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.260 N/A N/A a.1.1 Globin-like
View Download 0.259 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.258 N/A N/A d.67.3 Ribosome recycling factor, RRF
View Download 0.257 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.257 N/A N/A a.63.1 Apolipophorin-III
View Download 0.254 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.254 N/A N/A a.29.2 Bromodomain
View Download 0.249 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.247 N/A N/A d.79.2 Tubulin/Dihydroxyacetone kinase C-terminal domain
View Download 0.245 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.243 N/A N/A d.56.1 GroEL-intermediate domain like
View Download 0.243 N/A N/A d.15.4 2Fe-2S ferredoxin-like
View Download 0.243 N/A N/A a.47.2 t-snare proteins
View Download 0.243 N/A N/A a.7.8 GAT domain
View Download 0.242 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.241 N/A N/A a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.241 N/A N/A a.47.2 t-snare proteins
View Download 0.239 N/A N/A a.7.1 Spectrin repeat
View Download 0.238 N/A N/A a.7.8 GAT domain
View Download 0.238 N/A N/A d.79.2 Tubulin/Dihydroxyacetone kinase C-terminal domain
View Download 0.238 N/A N/A a.24.1 Apolipoprotein
View Download 0.234 N/A N/A a.4.1 Homeodomain-like
View Download 0.234 N/A N/A d.67.3 Ribosome recycling factor, RRF
View Download 0.223 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.218 N/A N/A a.47.2 t-snare proteins
View Download 0.218 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.218 N/A N/A f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.217 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.215 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.214 N/A N/A a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.213 N/A N/A a.74.1 Cyclin-like
View Download 0.212 N/A N/A a.47.2 t-snare proteins
View Download 0.211 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.211 N/A N/A a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.211 N/A N/A f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.209 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.208 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.208 N/A N/A a.25.1 Ferritin-like
View Download 0.207 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.204 N/A N/A d.80.1 Tautomerase/MIF
View Download 0.202 N/A N/A c.14.1 ClpP/crotonase
View Download 0.202 N/A N/A a.29.2 Bromodomain

Predicted Domain #3
Region A:
Residues: [195-323]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDDKPLDVHD YIKDAQKLHS SKCVLQIRMT DGKTLKHEFN SSETLNDVRK WVDVNRTDGD  60
   61 CPYSFHRGIP RVTFKDSDEL KTLETLELTP RSALLLKPLE TQNSGLSVTG MEGPSLLGRL 120
  121 YKGFSTWWH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.154902
Match: 1jruA_
Description: p47
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [324-436]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDKDPEVTSQ REETSKPNRH EVRSSTPLSG AASSSCFQYN NVREPVQSSA HASPMLTPSG  60
   61 TRYPSETNLT TSRSVSPNVF QFVNNDHQED PEDPTTFNGN NVHLEKKKDE DKK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.354 a.39.1 EF-hand
View Download 0.244 a.4.1 Homeodomain-like
View Download 0.296 a.77.1 DEATH domain
View Download 0.268 f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.354 a.39.1 EF-hand
View Download 0.268 f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.244 a.4.1 Homeodomain-like
View Download 0.232 b.125.1 Lipoprotein localization factors LolAB
View Download 0.232 b.125.1 Lipoprotein localization factors LolAB


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle