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View Structure Prediction Details

Protein: ERT1
Organism: Saccharomyces cerevisiae
Length: 529 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ERT1.

Description E-value Query
Range
Subject
Range
ERT1 - Transcriptional regulator of nonfermentable carbon utilization; GFP-fusion protein localizes to cyto...
ERT1_YEAST - Transcription activator of gluconeogenesis ERT1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2...
0.0 [1..529] [1..529]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
8.0E-53 [3..455] [30..522]
gi|18376338 - gi|18376338|emb|CAD21084.1| conserved hypothetical protein [Neurospora crassa]
gi|164427437, gi... - gi|164427437|ref|XP_955876.2| hypothetical protein NCU03489 [Neurospora crassa OR74A], gi|157071742|...
7.0E-48 [13..229] [8..227]
gi|1706177 - sp|P52959|CT1B_FUSSO CUTINASE TRANSCRIPTION FACTOR 1 BETA
CTF1B_FUSSO - Cutinase transcription factor 1 beta OS=Fusarium solani subsp. pisi GN=CTF1-BETA PE=2 SV=1
3.0E-43 [3..191] [14..231]
SPAC139.03 - transcription factor, zf-fungal binuclear cluster type
YII3_SCHPO - Uncharacterized transcriptional regulatory protein C139.03 OS=Schizosaccharomyces pombe (strain 972 ...
8.0E-38 [21..199] [4..183]
gi|166488 - gi|166488|gb|AAA32686.1| regulatory protein
4.0E-21 [39..168] [18..153]
AMDR_EMENI - Acetamidase regulatory protein OS=Emericella nidulans GN=amdR PE=4 SV=1
5.0E-21 [39..162] [19..150]

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Predicted Domain #1
Region A:
Residues: [1-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCTPDENDYK TSTDPDTSAN TNHTLEKKKR KKRKNTNVAC VNCSRLHVSC EAKRPCLRCI  60
   61 SKGLTATCVD APRKKSKYLA GIPNRELPMN IQPDLPPRKI MIPIYNNSSN SSLNVNNMGE 120
  121 QQKFTSPQHI VHKAKFLSNA ADSEYSILSN IIYQDTLSNK IPIDILYSNT N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.0
Match: 1hwtC_
Description: Hap1 (Cyp1); HAP1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.46021754022299 bayes_pls_golite062009
nucleic acid binding 3.26455198324141 bayes_pls_golite062009
DNA binding 3.25588366587125 bayes_pls_golite062009
binding 2.32645838605286 bayes_pls_golite062009
transcription factor activity 2.20574348407066 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.54700248976411 bayes_pls_golite062009
sequence-specific DNA binding 1.34348800608209 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.28573362149629 bayes_pls_golite062009
transcription activator activity 0.335097584119319 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [172-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STSNSTIGNS SNNSPTGTNT SPEETEMEKI RQLYSEQRAN IPPHPYPSSN QNVYSILLGP  60
   61 NSAKIVASQV NLFANHFPLV PVDSADNSLN FKRLLPRDPS EKSSQINWDS SINQYYLNSE 120
  121 TVTFPELAIP LKRRKNHLVS VSLESCSPDA ANIKSNVEWE HSLRYSTPME IYTSINAPFS 180
  181 HT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.226 c.1.16 Bacterial luciferase-like
View Download 0.356 a.185.1 Gametocyte protein Pfg27
View Download 0.356 a.185.1 Gametocyte protein Pfg27
View Download 0.226 c.1.16 Bacterial luciferase-like

Predicted Domain #3
Region A:
Residues: [354-529]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGFHHLLVYL KHRFNQQDLV KMCRSIAEFR PIFIACSVTL TEEDMIFMEQ CYQRTLLEYV  60
   61 KFIAQIGTPT CIWRRNGQIS YVNEEFEILC GWTREELLNK MTFIVEIMDD ESVRDYFKTL 120
  121 SKVAYRDFRG SEKMKVCRLL SPIKGKIIHC CCMWTLKRDV SGLPLMILGN FMPILN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 13.346787
Match: PF00989
Description: PAS fold

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle