| Protein: | TDP1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 544 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TDP1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..544] | [1..544] |
|
|
0.0 | [18..536] | [105..589] |
|
|
0.0 | [71..538] | [135..576] |
|
|
0.0 | [75..539] | [137..591] |
|
|
0.0 | [60..533] | [2..514] |
|
|
0.0 | [74..542] | [28..439] |
|
|
0.0 | [185..536] | [1..324] |
|
Region A: Residues: [1-222] |
1 11 21 31 41 51
| | | | | |
1 MSRETNFNGT KRKRSDVAEK VAQRWKSVRY SAEMENMAPV NSNNDSDDCV IVSESKIIDL 60
61 TNQEQDLSER IETNDTAKGA VFKLMKSDFY EREDFMGEVE DMITLKDIFG TETLKRSILF 120
121 SFQYELDFLL RQFHQNVENI TIVGQKGTIM PIEARAMDAT LAVILKKVKL IEITMPPFAS 180
181 HHTKLIINFY DNGECKIFLP SNNFTSMETN LPQQVCWCSP LL
|
| Detection Method: |  |
| Confidence: | 289.9897 |
| Match: | 1jy1A_ |
| Description: | Tyrosyl-DNA phosphodiesterase TDP1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| 3'-tyrosyl-DNA phosphodiesterase activity | 1.46693175347055 | bayes_pls_golite062009 |
| tyrosyl-DNA phosphodiesterase activity | 1.46693175347055 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.41591686174898 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.29668490323599 | bayes_pls_golite062009 |
| single-stranded DNA binding | 1.29429720882252 | bayes_pls_golite062009 |
| catalytic activity | 1.29236214516383 | bayes_pls_golite062009 |
| binding | 1.26667168593698 | bayes_pls_golite062009 |
| nucleic acid binding | 0.926017334343152 | bayes_pls_golite062009 |
| DNA binding | 0.840595330626189 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.235198647671849 | bayes_pls_golite062009 |
| protein binding | 0.162885453822356 | bayes_pls_golite062009 |
|
Region A: Residues: [223-268] |
1 11 21 31 41 51
| | | | | |
1 KIGKEGLPVP FKRSLIEYLN SYHLKDIDEL ITKSVEEVNF APLSEL
|
| Detection Method: | |
| Confidence: | 289.9897 |
| Match: | 1jy1A_ |
| Description: | Tyrosyl-DNA phosphodiesterase TDP1 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [269-287] |
1 11 21 31 41 51
| | | | | |
1 EFVYSTPSKF QSSGLLSFY
|
|
Region B: Residues: [461-486] |
1 11 21 31 41 51
| | | | | |
1 YTSANLSQTA WGTVSRKPRN YEAGVL
|
| Detection Method: | |
| Confidence: | 289.9897 |
| Match: | 1jy1A_ |
| Description: | Tyrosyl-DNA phosphodiesterase TDP1 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [288-460] |
1 11 21 31 41 51
| | | | | |
1 NKLEKLSAGT SASDTAKHYL CQTSSIGTSL SRARDENLWT HLMIPLFTGI MSPPAKDTAG 60
61 RKKAEILPTN SLINEYSQRK IKPYIIFPTE QEFVTSPLKW SSSGWFHFQY LQKKSYYEML 120
121 RNKFKVFYKQ DPAMVTRRRG TTPAHSKFYM HCATNSAGPC DASQVFKELE WCL
|
|
Region B: Residues: [487-544] |
1 11 21 31 41 51
| | | | | |
1 YHSRRLANTR KVTCRTFTRD RRGCAGNPTH VAVPFTLPVI PYDLAEDECF CLARHEND
|
| Detection Method: | |
| Confidence: | 289.9897 |
| Match: | 1jy1A_ |
| Description: | Tyrosyl-DNA phosphodiesterase TDP1 |
| Matching Structure (courtesy of the PDB): |
|
