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View Structure Prediction Details

Protein: EXO84
Organism: Saccharomyces cerevisiae
Length: 753 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EXO84.

Description E-value Query
Range
Subject
Range
gi|190408739 - gi|190408739|gb|EDV12004.1| exocyst complex component EXO84 [Saccharomyces cerevisiae RM11-1a]
EXO84_YEAST - Exocyst complex component EXO84 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EXO84 PE...
EXO84 - Essential protein with dual roles in spliceosome assembly and exocytosis; the exocyst complex (Sec3p...
gi|151946494 - gi|151946494|gb|EDN64716.1| exocyst complex component [Saccharomyces cerevisiae YJM789]
0.0 [1..753] [1..753]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [168..748] [4..541]
SPAC6F12.08c - exocyst complex subunit Exo84
gi|19114206 - gi|19114206|ref|NP_593294.1| hypothetical protein SPAC6F12.08c [Schizosaccharomyces pombe 972h-]
0.0 [111..744] [4..569]
exo84-PA - This gene is referred to in FlyBase by the symbol Dmel\exo84 (CG6095, FBgn0260946). It is a protein_...
0.0 [175..745] [2..493]
gi|27754564, gi|... - gi|28393871|gb|AAO42343.1| unknown protein [Arabidopsis thaliana], gi|27754564|gb|AAO22729.1| unknow...
2.0E-67 [449..737] [38..337]

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Predicted Domain #1
Region A:
Residues: [1-157]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVEFSLKKAR NNWKHVKKSA SSPAKQKTPP SPAKPKQKTK KNPYSDLKDP ATSYTLPTIN  60
   61 ARERSRVATS MQRRLSIHNT NYAPPTLDYS MPLPDMPNMI VPNDNVDSSH NNSSFTTENE 120
  121 SVSSKGPSNS LNLSTADLSL NDSSYNKVPA RSAMRNT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [158-279]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNPSGSNDPF NNSTSLRKML ANPHFNAKDF VHDKLGNASA ITIDKFTSNL TDLSIQVQEE  60
   61 VKLNINKSYN EIMTVNNDLN VAMLELKRVR ANINDLNEVL DQCTKIAEKR LQLQDQIDQE 120
  121 RQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.824 N/A N/A a.7.8 GAT domain

Predicted Domain #3
Region A:
Residues: [280-341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNFNNVESHS NSPALLPPLK AGQNGNLMRR DRSSVLILEK FWDTELDQLF KNVEGAQKFI  60
   61 NS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [342-480]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKGRHILMNS ANWMELNTTT GKPLQMVQIF ILNDLVLIAD KSRDKQNDFI VSQCYPLKDV  60
   61 TVTQEEFSTK RLLFKFSNSN SSLYECRDAD ECSRLLDVIR KAKDDLCDIF HVEEENSKRI 120
  121 RESFRYLQST QQTPGRENN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.09691
Match: 1awe__
Description: Son of sevenless-1 (sos-1)
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [481-753]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSPNKNKRRS MGGSITPGRN VTGAMDQYLL QNLTLSMHSR PRSRDMSSTA QRLKFLDEGV  60
   61 EEIDIELARL RFESAVETLL DIESQLEDLS ERISDEELML LNLISLKIEQ RREAISSKLS 120
  121 QSILSSNEIV HLKSGTENMI KLGLPEQALD LFLQNRSNFI QDLILQIGSV DNPTNYLTQL 180
  181 AVIRFQTIKK TVEDFQDIFK ELGAKISSIL VDWCSDEVDN HFKLIDKQLL NDEMLSPGSI 240
  241 KSSRKQIDGL KAVGLDFVYK LDEFIKKNSD KIR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle