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View Structure Prediction Details

Protein: YBR028C
Organism: Saccharomyces cerevisiae
Length: 525 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YBR028C.

Description E-value Query
Range
Subject
Range
YPK3_YEAST - Serine/threonine-protein kinase YPK3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPK...
YBR028C - Putative protein kinase, possible substrate of cAMP-dependent protein kinase (PKA)
0.0 [1..525] [1..525]
KPC2_APLCA - Calcium-independent protein kinase C OS=Aplysia californica GN=PRKC2 PE=1 SV=1
0.0 [9..518] [285..730]
gi|183396893, gi... - gi|183396893|gb|AAI65948.1| Protein kinase C, epsilon [synthetic construct], gi|117616658|gb|ABK4234...
KPCE_MOUSE - Protein kinase C epsilon type OS=Mus musculus GN=Prkce PE=1 SV=1
0.0 [10..520] [281..736]
gi|16648134 - gi|16648134|gb|AAL25332.1| GH13631p [Drosophila melanogaster]
0.0 [10..519] [105..547]
PRKCE - protein kinase C, epsilon
gi|168279093 - gi|168279093|dbj|BAG11426.1| protein kinase C epsilon type [synthetic construct]
0.0 [10..520] [281..736]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [10..520] [281..735]
KPCE_RABIT - Protein kinase C epsilon type OS=Oryctolagus cuniculus GN=PRKCE PE=2 SV=1
0.0 [10..520] [281..735]
gi|206183 - gi|206183|gb|AAA41872.1| protein kinase C epsilon subspecies
KPCE_RAT - Protein kinase C epsilon type OS=Rattus norvegicus GN=Prkce PE=1 SV=1
0.0 [10..520] [281..736]

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Predicted Domain #1
Region A:
Residues: [1-89]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIFSLDEELH RVSLDDKKND IKVDYSSAIY NDINHEQGSS ITYEESINHL SVHSNAIPLN  60
   61 GMSPAHRMRR RSSAYSKFPI LTPPNTRRF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.457 b.55.1 PH domain-like
View Download 0.644 d.58.12 eEF-1beta-like
View Download 0.644 d.58.12 eEF-1beta-like
View Download 0.464 d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.464 d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.458 g.10.1 Hairpin loop containing domain-like
View Download 0.458 g.10.1 Hairpin loop containing domain-like
View Download 0.457 b.55.1 PH domain-like
View Download 0.451 d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.451 d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.418 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.409 d.58.7 RNA-binding domain, RBD
View Download 0.405 b.15.1 HSP20-like chaperones
View Download 0.401 a.39.1 EF-hand
View Download 0.383 b.84.1 Single hybrid motif
View Download 0.377 d.19.1 MHC antigen-recognition domain
View Download 0.367 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.357 d.58.7 RNA-binding domain, RBD
View Download 0.356 d.58.7 RNA-binding domain, RBD
View Download 0.353 d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.347 a.4.5 "Winged helix" DNA-binding domain
View Download 0.344 d.101.1 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
View Download 0.340 d.58.3 Protease propeptides/inhibitors
View Download 0.328 d.58.3 Protease propeptides/inhibitors
View Download 0.322 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.318 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.313 d.58.10 Acylphosphatase-like
View Download 0.304 b.84.2 Rudiment single hybrid motif
View Download 0.294 b.1.1 Immunoglobulin
View Download 0.283 d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.259 d.202.1 Transcription factor NusA, N-terminal domain
View Download 0.256 d.235.1 Hypothetical protein Yhr087W
View Download 0.253 d.57.1 DNA damage-inducible protein DinI
View Download 0.243 d.58.5 GlnB-like
View Download 0.243 d.206.1 YggU-like
View Download 0.242 d.201.1 SRP19
View Download 0.236 d.198.1 Type III secretory system chaperone
View Download 0.229 a.1.1 Globin-like
View Download 0.225 a.60.11 Hypothetical protein YjbJ
View Download 0.225 d.58.17 Metal-binding domain
View Download 0.221 b.11.1 gamma-Crystallin-like
View Download 0.205 d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.204 d.58.8 Viral DNA-binding domain
View Download 0.202 a.138.1 Multiheme cytochromes

Predicted Domain #2
Region A:
Residues: [90-119]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SITGSDAMRT NTNRLSITPQ DIISSNIGEN 

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [198-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTFAERSILS EIEHPNIVKL 

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [233-478]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YIPGGELFYH LKEHGTLDET TVSFYAAEIS CALRFLHTKG VVYRDLKPEN CLLNQRGHLV  60
   61 LTDFGLSKKS ANDSAVDEED PENVNALYSI IGTPEYCAPE ILLGKAYSQN CDWYSLGCLL 120
  121 YDMLVGKPPY TGSNHKVIIN KIQQNKQGPK IPFYLSEGMK DILNALLKKE TAKRWNVDKY 180
  181 WAKTGANNKP TKSKKKKSGA ARTSLFTEHF IFRKIDWKLL ESGQLQKTTL GPIVPVITDL 240
  241 ELAENF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 618.9897
Match: 1ctpE_
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [120-197]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELSRNLHDFK PVRVLGQGAY GKVLLVKDVN TSKLYAMKQL RKAEILISQT ATDSKREDED  60
   61 KNDGNNNDND DGLSKRLE

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [218-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FYSFHDNSKL YLLLQ

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [479-525]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTEFTSMSYE ETYTDSKPIN INSVSKSPDM FKGFSYKASG SYLEKYF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 618.9897
Match: 1ctpE_
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle