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View Structure Prediction Details

Protein: YBR028C
Organism: Saccharomyces cerevisiae
Length: 525 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YBR028C.

Description E-value Query
Range		 Subject
Range
YPK3_YEAST - Serine/threonine-protein kinase YPK3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPK...
YBR028C - Putative protein kinase, possible substrate of cAMP-dependent protein kinase (PKA)
 0.0 [1..525] [1..525]
KPC2_APLCA - Calcium-independent protein kinase C OS=Aplysia californica GN=PRKC2 PE=1 SV=1
 0.0 [9..518] [285..730]
gi|183396893, gi... - gi|183396893|gb|AAI65948.1| Protein kinase C, epsilon [synthetic construct], gi|117616658|gb|ABK4234...
KPCE_MOUSE - Protein kinase C epsilon type OS=Mus musculus GN=Prkce PE=1 SV=1
 0.0 [10..520] [281..736]
gi|16648134 - gi|16648134|gb|AAL25332.1| GH13631p [Drosophila melanogaster]
 0.0 [10..519] [105..547]
PRKCE - protein kinase C, epsilon
gi|168279093 - gi|168279093|dbj|BAG11426.1| protein kinase C epsilon type [synthetic construct]
 0.0 [10..520] [281..736]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [10..520] [281..735]
KPCE_RABIT - Protein kinase C epsilon type OS=Oryctolagus cuniculus GN=PRKCE PE=2 SV=1
 0.0 [10..520] [281..735]
gi|206183 - gi|206183|gb|AAA41872.1| protein kinase C epsilon subspecies
KPCE_RAT - Protein kinase C epsilon type OS=Rattus norvegicus GN=Prkce PE=1 SV=1
 0.0 [10..520] [281..736]

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Predicted Domain #1
Region A:
Residues: [1-89] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIFSLDEELH RVSLDDKKND IKVDYSSAIY NDINHEQGSS ITYEESINHL SVHSNAIPLN  60
   61 GMSPAHRMRR RSSAYSKFPI LTPPNTRRF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [90-119] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SITGSDAMRT NTNRLSITPQ DIISSNIGEN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [198-217] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTFAERSILS EIEHPNIVKL

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [233-478] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YIPGGELFYH LKEHGTLDET TVSFYAAEIS CALRFLHTKG VVYRDLKPEN CLLNQRGHLV  60
   61 LTDFGLSKKS ANDSAVDEED PENVNALYSI IGTPEYCAPE ILLGKAYSQN CDWYSLGCLL 120
  121 YDMLVGKPPY TGSNHKVIIN KIQQNKQGPK IPFYLSEGMK DILNALLKKE TAKRWNVDKY 180
  181 WAKTGANNKP TKSKKKKSGA ARTSLFTEHF IFRKIDWKLL ESGQLQKTTL GPIVPVITDL 240
  241 ELAENF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 618.9897
Match: 1ctpE_
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [120-197] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELSRNLHDFK PVRVLGQGAY GKVLLVKDVN TSKLYAMKQL RKAEILISQT ATDSKREDED  60
   61 KNDGNNNDND DGLSKRLE

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [218-232] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FYSFHDNSKL YLLLQ

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [479-525] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTEFTSMSYE ETYTDSKPIN INSVSKSPDM FKGFSYKASG SYLEKYF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 618.9897
Match: 1ctpE_
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle