YRC Public Data Repository - Protein Structure Prediction

Protein:	YBL055C
Organism:	Saccharomyces cerevisiae
Length:	418 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YBL055C.

Description	E-value	Query Range	Subject Range
YBF5_YEAST - Deoxyribonuclease Tat-D OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YBL055C PE=1 SV=... YBL055C - 3'-->5' exonuclease and endonuclease with a possible role in apoptosis; has similarity to mammalian ...	0.0	[1..418]	[1..418]
TATDN1 - TatD DNase domain containing 1	2.0E-71	[34..416]	[2..293]
YNF8_SCHPO - Deoxyribonuclease Tat-D OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=pi038 PE=3 SV=1 SPBC17A3.08 - TatD	3.0E-70	[27..418]	[3..312]
gi\|25318571 - pir\|\|E97830 hypothetical protein RC1045 [imported] - Rickettsia conorii (strain Malish 7) gi\|15620164, gi\|... - gi\|15892968\|ref\|NP_360682.1\| hypothetical protein RC1045 [Rickettsia conorii str. Malish 7], gi\|1562...	6.0E-62	[38..379]	[2..297]
YABD_BACSU - Uncharacterized metal-dependent hydrolase YabD OS=Bacillus subtilis (strain 168) GN=yabD PE=3 SV=1 YABD_BACSU - Uncharacterized deoxyribonuclease YabD OS=Bacillus subtilis GN=yabD PE=3 SV=1 gi\|221312170 - gi\|221312170\|ref\|ZP_03593975.1\| hypothetical protein BsubsN3_00195 [Bacillus subtilis subsp. subtili... gi\|221321366 - gi\|221321366\|ref\|ZP_03602660.1\| hypothetical protein BsubsS_00195 [Bacillus subtilis subsp. subtilis... gi\|221317103 - gi\|221317103\|ref\|ZP_03598397.1\| hypothetical protein BsubsJ_00195 [Bacillus subtilis subsp. subtilis...	2.0E-61	[38..377]	[2..252]
gi\|164427480, gi... - gi\|164427480\|ref\|XP_956817.2\| hypothetical protein NCU03538 [Neurospora crassa OR74A], gi\|157071760\|... gi\|16944535 - gi\|16944535\|emb\|CAD11331.1\| conserved hypothetical protein [Neurospora crassa]	2.0E-60	[26..353]	[4..323]
gi\|19745392, gi\|... - gi\|19747500\|gb\|AAL97027.1\| conserved hypothetical protein [Streptococcus pyogenes MGAS8232], gi\|1974...	9.0E-60	[25..377]	[8..271]
gi\|170662728, gi... - gi\|170662728\|gb\|EDT15411.1\| hydrolase, TatD family [Clostridium perfringens E str. JGS1987], gi\|1682... gi\|168209758, gi... - gi\|170712156\|gb\|EDT24338.1\| hydrolase, TatD family [Clostridium perfringens B str. ATCC 3626], gi\|16... gi\|18311502, gi\|... - gi\|18311502\|ref\|NP_563436.1\| hydrolase, TatD family [Clostridium perfringens str. 13], gi\|18146186\|d... gi\|168217637, gi... - gi\|182380288\|gb\|EDT77767.1\| hydrolase, TatD family [Clostridium perfringens NCTC 8239], gi\|168217637... gi\|177910544, gi... - gi\|182624326\|ref\|ZP_02952111.1\| hydrolase, TatD family [Clostridium perfringens D str. JGS1721], gi\|...	8.0E-59	[35..377]	[2..254]
gi\|13621535, gi\|... - gi\|15674440\|ref\|NP_268614.1\| hypothetical protein SPy_0260 [Streptococcus pyogenes M1 GAS], gi\|13621... gi\|71852816, gi\|... - gi\|71910034\|ref\|YP_281584.1\| sec-independent protein translocase protein [Streptococcus pyogenes MGA...	1.0E-58	[25..377]	[8..271]
gi\|124301002, gi... - gi\|18418353\|ref\|NP_568352.1\| tatD-related deoxyribonuclease family protein [Arabidopsis thaliana], g...	3.0E-58	[36..417]	[1..297]

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Predicted Domain #1

Region A:
Residues: [1-418]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWGILLKSSN KSCSRLWKPI LTQYYSMTST ATDSPLKYYD IGLNLTDPMF HGIYNGKQYH  60
   61 PADYVKLLER AAQRHVKNAL VTGSSIAESQ SAIELVSSVK DLSPLKLYHT IGVHPCCVNE 120
  121 FADASQGDKA SASIDNPSMD EAYNESLYAK VISNPSFAQG KLKELYDLMN QQAKPHDTSF 180
  181 RSIGEIGLDY DRFHYSSKEM QKVFFEEQLK ISCLNDKLSS YPLFLHMRSA CDDFVQILER 240
  241 FIAGFTDERD TFQLQKLGAS SSSGFYKFHP DRKLVVHSFT GSAIDLQKLL NLSPNIFIGV 300
  301 NGCSLRTEEN LAVVKQIPTE RLLLETDAPW CEIKRTHASF QYLAKYQEVR DFEYPAFKSV 360
  361 KKNKLADKLN AEELYMVKGR NEPCNMEQVA IVVSEVKDVD LATLIDTTWK TTCKIFGE

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	14.89
Match:	1pscA
Description:	Phosphotriesterase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	3.06979421893431	bayes_pls_golite062009
catalytic activity	1.70199291046899	bayes_pls_golite062009
transcription regulator activity	1.20760795918714	bayes_pls_golite062009
nucleic acid binding	1.15067018524191	bayes_pls_golite062009
binding	1.06005411409792	bayes_pls_golite062009
DNA binding	0.877200496150201	bayes_pls_golite062009
deoxyribonuclease activity	0.375250302403787	bayes_pls_golite062009
transcription factor activity	0.361973962821982	bayes_pls_golite062009
protein binding	0.0854348074331311	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: