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View Structure Prediction Details

Protein: PRP45
Organism: Saccharomyces cerevisiae
Length: 379 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRP45.

Description E-value Query
Range
Subject
Range
gi|207348024 - gi|207348024|gb|EDZ74005.1| YAL032Cp-like protein [Saccharomyces cerevisiae AWRI1631]
PRP45 - Protein required for pre-mRNA splicing; associates with the spliceosome and interacts with splicing ...
PRP45_YEAST - Pre-mRNA-processing protein 45 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRP45 PE=...
0.0 [1..379] [1..379]
gi|61357157, gi|... - gi|61357163|gb|AAX41344.1| SKI interacting protein [synthetic construct], gi|61357157|gb|AAX41343.1|...
SNW1 - SNW domain containing 1
gi|114654181 - gi|114654181|ref|XP_510097.2| PREDICTED: SKI-interacting protein isoform 3 [Pan troglodytes]
0.0 [3..368] [83..497]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1..312] [1..312]
Bx42-PA, FBpp0305943 - The gene Bx42 is referred to in FlyBase by the symbol Dmel\Bx42 (CG8264, FBgn0004856). It is a prote...
gi|220954608, gi... - gi|220954608|gb|ACL89847.1| Bx42-PA [synthetic construct], gi|220944828|gb|ACL84957.1| CG8264-PA [sy...
0.0 [3..369] [86..509]
SKIP_ARATH - SNW/SKI-interacting protein OS=Arabidopsis thaliana GN=SKIP PE=1 SV=1
0.0 [5..372] [93..555]
prp45 - transcriptional regulator Prp45
PRP45_SCHPO - Pre-mRNA-processing protein 45 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=prp45 PE=1 ...
0.0 [4..371] [89..541]
gi|85101656 - gi|85101656|ref|XP_961188.1| pre-mRNA splicing factor prp45 [Neurospora crassa OR74A]
gi|32404974, gi|... - gi|32404974|ref|XP_323100.1| hypothetical protein ( (AL451018) probable puff-specific nuclear protei...
2.0E-99 [3..372] [92..526]
gi|12843873 - gi|12843873|dbj|BAB26144.1| unnamed protein product [Mus musculus]
5.0E-78 [119..368] [1..294]
gi|60474007, gi|... - gi|66825409|ref|XP_646059.1| nuclear receptor coactivator NC0A-62 [Dictyostelium discoideum AX4], gi...
SNWA_DICDI - Protein snwA OS=Dictyostelium discoideum GN=snwA PE=1 SV=1
3.0E-70 [7..255] [113..358]

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Predicted Domain #1
Region A:
Residues: [1-57]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSNRLPPPK HSQGRVSTAL SSDRVEPAIL TDQIAKNVKL DDFIPKRQSN FELSVPL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [58-312]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTKAEIQECT ARTKSYIQRL VNAKLANSNN RASSRYVTET HQAPANLLLN NSHHIEVVSK  60
   61 QMDPLLPRFV GKKARKVVAP TENDEVVPVL HMDGSNDRGE ADPNEWKIPA AVSNWKNPNG 120
  121 YTVALERRVG KALDNENNTI NDGFMKLSEA LENADKKARQ EIRSKMELKR LAMEQEMLAK 180
  181 ESKLKELSQR ARYHNGTPQT GAIVKPKKQT STVARLKELA YSQGRDVSEK IILGAAKRSE 240
  241 QPDLQYDSRF FTRGA

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 109.853872
Match: PF02731
Description: SKIP/SNW domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [313-379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NASAKRHEDQ VYDNPLFVQQ DIESIYKTNY EKLDEAVNVK SEGASGSHGP IQFTKAESDD  60
   61 KSDNYGA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 2.59005615358803 bayes_pls_golite062009
protein binding 2.41769888237582 bayes_pls_golite062009
tubulin binding 0.684160753873506 bayes_pls_golite062009
cytoskeletal protein binding 0.538779930266561 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [298-379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPDLQYDSRF FTRGANASAK RHEDQVYDNP LFVQQDIESI YKTNYEKLDE AVNVKSEGAS  60
   61 GSHGPIQFTK AESDDKSDNY GA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle