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View Structure Prediction Details

Protein: VPS8
Organism: Saccharomyces cerevisiae
Length: 1176 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VPS8.

Description E-value Query
Range
Subject
Range
gi|3882329 - gi|3882329|dbj|BAA34524.1| KIAA0804 protein [Homo sapiens]
0.0 [423..1171] [378..1096]
CG10144-PA - This gene is referred to in FlyBase by the symbol Dmel\CG10144 (CG10144, FBgn0035704). It is a prote...
0.0 [416..1171] [530..1193]
VPS41_ARATH, VP4... - (P93043) Vacuolar assembly protein VPS41 homolog, (P93043) Vacuolar assembly protein VPS41 homolog
9.0E-92 [757..1158] [552..918]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-88 [729..1174] [91..586]
VPS41_SOLLC - Vacuolar protein sorting-associated protein 41 homolog OS=Solanum lycopersicum GN=VPS41 PE=2 SV=1
1.0E-87 [755..1159] [548..903]

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Predicted Domain #1
Region A:
Residues: [1-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTSKGCVLI FNYNEHLQTI LVPTLSEDPS IHSIRSPVKS IVICSDGTHV AASYETGNIC  60
   61 IWNLNVGYRV KPTSEPTNGM TPTPALPAVL HIDDHVNKEI TGLDFFGARH TALIVSDRTG 120
  121 KVSLYNGYRR GFWQLVYNSK KILDVNSSKE KLIRSKLSPL ISREKISTNL LSVLTTTHFA 180
  181 LILLSPHVSL MFQETVEPSV QNSLVVNSSI SWTQNCSRVA YSVNNKISVI SISSSDFNVQ 240
  241 SASHSPEFAE SILSIQWIDQ LLLGVLTISH QFLVLHPQHD FKILLRLDFL IHDLMIPPNK 300
  301 YFVISRRSFY LLTNYSFKIG KFVSWSDITL RHILKGDYLG ALEFIESLLQ PYCPLANLLK 360
  361 LDNNTEERTK QLMEPFYNLS LAALRFLIKK DN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [393-588]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADYNRVYQLL MVVVRVLQQS SKKLDSIPSL DVFLEQGLEF FELKDNAVYF EVVANIVAQG  60
   61 SVTSISPVLF RSIIDYYAKE ENLKVIEDLI IMLNPTTLDV DLAVKLCQKY NLFDLLIYIW 120
  121 NKIFDDYQTP VVDLIYRISN QSEKCVIFNG PQVPPETTIF DYVTYILTGR QYPQNLSISP 180
  181 SDKCSKIQRE LSAFIF

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 20.229148
Match: PF00637
Description: Region in Clathrin and VPS

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [589-800]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGFSIKWPSN SNHKLYICEN PEEEPAFPYF HLLLKSNPSR FLAMLNEVFE ASLFNDDNDM  60
   61 VASVGEAELV SRQYVIDLLL DAMKDTGNSD NIRVLVAIFI ATSISKYPQF IKVSNQALDC 120
  121 VVNTICSSRV QGIYEISQIA LESLLPYYHS RTTENFILEL KEKNFNKVLF HIYKSENKYA 180
  181 SALSLILETK DIEKEYNTDI VSITDYILKK CP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [801-1014]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGSLECGKVT EVIETNFDLL LSRIGIEKCV TIFSDFDYNL HQEILEVKNE ETQQKYLDKL  60
   61 FSTPNINNKV DKRLRNLHIE LNCKYKSKRE MILWLNGTVL SNAESLQILD LLNQDSNFEA 120
  121 AAIIHERLES FNLAVRDLLS FIEQCLNEGK TNISTLLESL RRAFDDCNSA GTEKKSCWIL 180
  181 LITFLITLYG KYPSHDERKD LCNKLLQEAF LGLV

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 13.585027
Match: PF00637
Description: Region in Clathrin and VPS

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1015-1176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSKSSSQKDS GGEFWEIMSS VLEHQDVILM KVQDLKQLLL NVFNTYKLER SLSELIQKII  60
   61 EDSSQDLVQQ YRKFLSEGWS IHTDDCEICG KKIWGAGLDP LLFLAWENVQ RHQDMISVDL 120
  121 KTPLVIFKCH HGFHQTCLEN LAQKPDEYSC LICQTESNPK IV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle