YRC Public Data Repository - Protein Structure Prediction

Protein:	OMH3_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	378 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OMH3_SCHPO.

Description	E-value	Query Range	Subject Range
KRE2_CANAL - Glycolipid 2-alpha-mannosyltransferase OS=Candida albicans GN=KRE2 PE=3 SV=1 gi\|238880609 - gi\|238880609\|gb\|EEQ44247.1\| alpha-1,2 mannosyltransferase KTR1 [Candida albicans WO-1] MNT1_CANAL - Glycolipid 2-alpha-mannosyltransferase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MNT1...	540.0	[0..55]	[377..100]
gi\|44985528 - gi\|44985528\|gb\|AAS54224.1\| AGL267Cp [Ashbya gossypii ATCC 10895] gi\|45200830, gi\|... - gi\|45200830\|ref\|NP_986400.1\| AGL267Cp [Ashbya gossypii ATCC 10895], gi\|44985528\|gb\|AAS54224.1\| AGL26...	535.0	[0..42]	[378..86]
gi\|49654834 - gi\|49654834\|emb\|CAG87338.1\| DEHA2D15708p [Debaryomyces hansenii] gi\|49654834, gi\|... - gi\|50421243\|ref\|XP_459167.1\| hypothetical protein DEHA0D17105g [Debaryomyces hansenii CBS767], gi\|49...	532.0	[0..42]	[377..81]
KTR1_YEAST - Alpha-1,2 mannosyltransferase KTR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KTR1 ... KTR1 - Alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; type II membrane pr...	531.0	[0..48]	[377..53]
gi\|1362240 - gi\|1362240\|pir\|\|S57713 probable mannosyl transferase - yeast (Candida albicans)	531.0	[0..43]	[376..120]
gi\|59802977 - gi\|59802977\|gb\|AAX07685.1\| glycolipid 2-alpha-mannosyltransferase-like protein [Magnaporthe grisea] gi\|145009235, gi... - gi\|39948507\|ref\|XP_363108.1\| conserved hypothetical protein [Magnaporthe grisea 70-15], gb\|EAA51170....	521.0	[0..40]	[376..92]
gi\|67524589, gi\|... - gi\|67524589\|ref\|XP_660356.1\| hypothetical protein AN2752.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	520.0	[0..44]	[377..42]

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Predicted Domain #1

Region A:
Residues: [1-378]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGIPKSSIYF CILLFCIISF YLQSSKDGPK ELKVKYVFLK KATAKQRGES SLTDSDYFPK  60
   61 QPNMNATLFM LCRNRDIKDA LVSIQSVEDR FNHRYHYPWT FMNDAPFTKE FITATSKMVS 120
  121 GDATYVQLNN EEWGIPINID LNRMLKSIRD MTDDKVIYGF SLSYRIMCRF NSGFFYRNKA 180
  181 LSHYDYYWRV EPGVEYSCDI PYDPFRKLSD ENKAYGFVIS MTDYYETLPS LWNVTRDFIH 240
  241 QNPQYLAQNN SLDFIVNDHQ GLSGDYNLCH FWSNFEIANL NFFRSPAYTD YFAHLDKNYG 300
  301 FFYERWGDAP VHSLAASLFL NKSQIHYFED FGYYHLPWYH CPTDVQSHAT ARCLCDPTGT 360
  361 IDYLPFSCAI KWLENINS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	140.0
Match:	1s4nA
Description:	Crystal structure of yeast alpha1,2-mannosyltransferase Kre2p/Mnt1p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
alpha-1,2-mannosyltransferase activity	6.0576932895264	bayes_pls_golite062009
mannosyltransferase activity	5.57855076532185	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	4.49413422196176	bayes_pls_golite062009
UDP-glycosyltransferase activity	4.08451171179562	bayes_pls_golite062009
acetylgalactosaminyltransferase activity	3.4614674054855	bayes_pls_golite062009
transferase activity	3.32517438937547	bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity	3.19923094610567	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.60650378115696	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.51696952719873	bayes_pls_golite062009
catalytic activity	1.88676710996045	bayes_pls_golite062009
nucleotidyltransferase activity	1.86990263440735	bayes_pls_golite062009
uridylyltransferase activity	1.27888067902271	bayes_pls_golite062009
binding	0.948692623641759	bayes_pls_golite062009
glucuronosyltransferase activity	0.36353543999278	bayes_pls_golite062009
protein binding	0.124656890356575	bayes_pls_golite062009
UDP-galactosyltransferase activity	0.10185872015123	bayes_pls_golite062009
galactosyltransferase activity	0.0931461042017721	bayes_pls_golite062009
acetylglucosaminyltransferase activity	0.0562130308868509	bayes_pls_golite062009
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	0.0339369954475406	bayes_pls_golite062009
intramolecular oxidoreductase activity	0.0122078907283503	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: