YRC Public Data Repository - Protein Structure Prediction

Protein:	DCTD_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	348 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DCTD_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|28950120 - gi\|28950120\|emb\|CAD70900.1\| probable dCMP deaminase [Neurospora crassa]	349.0	[0..4]	[347..3]
gi\|32412958, gi\|... - gi\|32412958\|ref\|XP_326959.1\| hypothetical protein [Neurospora crassa], gi\|28922452\|gb\|EAA31684.1\| hy... gi\|85100199 - gi\|85100199\|ref\|XP_960920.1\| hypothetical protein [Neurospora crassa OR74A]	348.0	[0..4]	[344..3]
gi\|46137423, gi\|... - gi\|46137423\|ref\|XP_390403.1\| hypothetical protein FG10227.1 [Gibberella zeae PH-1], gi\|42547227\|gb\|E...	328.0	[0..4]	[343..3]
gi\|38111350, gi\|... - gi\|39971965\|ref\|XP_367373.1\| hypothetical protein MGG_07298 [Magnaporthe grisea 70-15], gb\|EAA56943....	306.0	[0..4]	[342..3]
gi\|68482051, gi\|... - gi\|68482051\|ref\|XP_715043.1\| hypothetical protein CaO19.7243 [Candida albicans SC5314], gi\|46436646\|... orf19.7243 - orf19.7243 CGDID:CAL0003875 Assembly 19, Contig19-2507 (74080, 75093) CDS, translated using codon ta...	295.0	[0..4]	[348..3]
gi\|88184978, gi\|... - gi\|88184978\|gb\|EAQ92446.1\| hypothetical protein CHGG_00681 [Chaetomium globosum CBS 148.51], gi\|1161...	277.0	[0..9]	[344..34]
gi\|169623393, gi... - gi\|169623393\|ref\|XP_001805104.1\| hypothetical protein SNOG_14935 [Phaeosphaeria nodorum SN15], gi\|11...	269.0	[0..9]	[340..10]
gi\|70989807, gi\|... - gi\|70989807\|ref\|XP_749753.1\| deoxycytidylate deaminase [Aspergillus fumigatus Af293], gi\|66847384\|gb... gi\|159129162 - gi\|159129162\|gb\|EDP54276.1\| deoxycytidylate deaminase, putative [Aspergillus fumigatus A1163]	261.0	[0..4]	[320..3]
gi\|50420267, gi\|... - gi\|50420267\|ref\|XP_458666.1\| hypothetical protein DEHA0D05313g [Debaryomyces hansenii CBS767], gi\|49...	259.0	[0..4]	[348..3]
DCD1 - Deoxycytidine monophosphate (dCMP) deaminase required for dCTP and dTTP synthesis; expression is NOT... gi\|151944091 - gi\|151944091\|gb\|EDN62384.1\| dCMP deaminase [Saccharomyces cerevisiae YJM789] DCTD_YEAST - Deoxycytidylate deaminase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DCD1 PE=1 SV=2	257.0	[0..4]	[345..3]

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Predicted Domain #1

Region A:
Residues: [1-195]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTVGLTGPL CSGKDAVVEY LETKHGFNAI FRLPQLNEDG EYIYRTGDLV LGSVDDLISY  60
   61 LTPRWRERFV INGIHSPRLL SALLKRPFFL LVYIDAPIML RFNRYKTYVI LQCQHVVANF 120
  121 KFIVIILHAM CSVYSSLANT TLEEFCSIQD AAAFQSDNAG TRHRALANLL INNDSNIKLH 180
  181 LWEKLQKADL LNPNR

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.59
Match:	1ukyA
Description:	SUBSTRATE SPECIFICITY AND ASSEMBLY OF CATALYTIC CENTER DERIVED FROM TWO STRUCTURES OF LIGATED URIDYLATE KINASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.35750064574034	bayes_pls_golite062009
nucleic acid binding	1.05874829607695	bayes_pls_golite062009
catalytic activity	0.942640875796745	bayes_pls_golite062009
hydrolase activity	0.799258945993812	bayes_pls_golite062009
DNA binding	0.694429305067015	bayes_pls_golite062009
transcription regulator activity	0.319052597844854	bayes_pls_golite062009
protein binding	0.262528335081572	bayes_pls_golite062009
CTP synthase activity	0.227154659921775	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	0.205823354338506	bayes_pls_golite062009
purine nucleotide binding	0.144773327806905	bayes_pls_golite062009
nucleotide binding	0.140809536790465	bayes_pls_golite062009
purine ribonucleotide binding	0.134373265505829	bayes_pls_golite062009
ribonucleotide binding	0.134362467171752	bayes_pls_golite062009
structure-specific DNA binding	0.00206249447427331	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [196-348]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FRPSWDSYFM EMASLAAKRS NCMKRRVGCV LVRGNRVIAT GYNGTPRGAT NCNEGGCPRC  60
   61 NSASSCGKEL DTCLCLHAEE NALLEAGRER VGNNAILYCD TCPCLTCSVK ITQLGIKEVV 120
  121 YHTSYNMDSH TASLLQAAGV QLRQYIPPEN SIF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.69897
Match:	2hvvA
Description:	No description for 2hvvA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: