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View Structure Prediction Details

Protein: CG30372-PB
Organism: Drosophila melanogaster
Length: 1155 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG30372-PB.

Description E-value Query
Range
Subject
Range
gi|28981429 - gi|28981429|gb|AAH48818.1| Asap1 protein [Mus musculus]
571.0 [0..3] [1155..57]

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Predicted Domain #1
Region A:
Residues: [1-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPSLIAVSE FVEETRSDYS SPTTSTFASR MPDCRHTIGV LEERLEFDRE GLTKLKKAVK  60
   61 AIHNSGNTHV DNEMFMVRAL ERLGGKVIEQ DEPDIGAAFL KFSVVTKELS ALMKTLMQNI 120
  121 NNIVMFPVDS MLKSELRGVK GDMKRPFDKA AKDYEAKFIK IEKEKKAQAK EAGMVRTEID 180
  181 AAVVAEEMEK ERRLYQLQTC EYLLKYKDIK TKTGIELLQH LIEYYHALSN YFKDGLQTIE 240
  241 HFGTYIGDLS EKLHEIKQKQ DEDRRSLLDL RTVLRSTPDF ERVDNVPSSE SRSGGAGYSL 300
  301 HQLQGDKHHG VTRQGHLLKK SEGKVRRVWQ KRRCRVTSDG FLDIFHADES KPPTRVNLLT 360
  361 CQIKPVPDDK RGFDLISYNR PYHFQAEDEG DQKAWMAVLV NCKEKALTKA FQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.69897
Match: 2elbA
Description: No description for 2elbA was found.

Predicted functions:

Term Confidence Notes
binding 2.38944296108213 bayes_pls_golite062009
protein binding 1.8661085728568 bayes_pls_golite062009
GTPase regulator activity 1.37732998017634 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 1.35296416441022 bayes_pls_golite062009
enzyme regulator activity 0.982827080165016 bayes_pls_golite062009
small GTPase regulator activity 0.948484673406212 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 0.476813178401925 bayes_pls_golite062009
small GTPase binding 0.258301158180693 bayes_pls_golite062009
GTPase binding 0.223470840486454 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [413-719]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HANPQMSPSL VELQKTVIRY VQLLPGNDRC CDCGSRNDVT WISLNFGILV CIQCSGVHRD  60
   61 LGVHHSRIQS LTLDNLTTAN LLIARAMGNS TLNDIMEAKL GRGKLQHESS MEERYDFIRA 120
  121 KYVAKRYVMR TCSDDNDLRC DLEQAVVNAD MSQLLQVWAE GADLTCCLPS SDAGETALHL 180
  181 AVLREMGSTL HIVDFLIQNM PPKGLNKATN PAGLLDVTGK NTALHLCALH DRRECMKLLL 240
  241 RSGADYELKN SQNKTALDIA KEMGHNSCRE LIECAIKREK SAFDHINTDW NLPNEDGSTD 300
  301 FSDDETV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.154902
Match: 1dcqA
Description: Pyk2-associated protein beta; Pyk2-associated protein beta ARF-GAP domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [720-789]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDERKSRSRP PSFAGGDSPV LRSRSSTCDS IQSSSSPIAN CPSRQFTLPS GLPSYTHSAG  60
   61 TSPKQHISVG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.522879
Match: 1ycsB
Description: 53BP2
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [790-968]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QYLGSATNVG GNGPGNGGSS PSSASSQSVR AARNSLNMQS DLGGHVTGAR KSTSTANMNS  60
   61 LKKRTAPAPP PGTLGSASSS SFYGTLPHPP RHSQNFDASD IRAINHKNQS LDVAYGTLPH 120
  121 LRSVESSPRG GGGYGYGVSQ DPGGSGNGSN NSLMPAMTTF GHKRSPSGES LNRNIHLAG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [969-1036]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKLVLPPTGE LPTLKHVDKS ALTRPKIPPP GPPSEREISN GQSNESISSM DEGPVAPPRK  60
   61 LVNQSANF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1037-1155]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDYESWHTDM DSSGGGLDHS AESNVSSSDN DRLNSSPDNP SKTGGAGLGG KFHYNGQRRC  60
   61 RALYDCVADN DDELEFKEGE ILIVLNERTD DENWMEGIIE GQPTRKGMFP VSFVHMLPD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.221849
Match: 1udlA
Description: The solution structure of the fifth SH3 domain of intersectin 2 (KIAA1256)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.16769365096483 bayes_pls_golite062009
protein binding 1.83074889220756 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle