YRC Public Data Repository - Protein Structure Prediction

Protein:	YA7B_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	958 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YA7B_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|46108248, gi\|... - gi\|46108248\|ref\|XP_381182.1\| hypothetical protein FG01006.1 [Gibberella zeae PH-1], gi\|42544966\|gb\|E...	431.0	[0..4]	[955..110]
gi\|85111690 - gi\|85111690\|ref\|XP_964057.1\| hypothetical protein NCU02632 [Neurospora crassa OR74A] gi\|32422775, gi\|... - gi\|32422775\|ref\|XP_331831.1\| hypothetical protein [Neurospora crassa], gi\|28925819\|gb\|EAA34821.1\| hy...	415.0	[0..55]	[957..229]
gi\|67526415, gi\|... - gi\|67526415\|ref\|XP_661269.1\| hypothetical protein AN3665.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	409.0	[0..23]	[951..245]
gi\|114194703, gi... - gi\|115389604\|ref\|XP_001212307.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	405.0	[0..10]	[957..136]
gi\|169764887 - gi\|169764887\|ref\|XP_001816915.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83764769 - gi\|83764769\|dbj\|BAE54913.1\| unnamed protein product [Aspergillus oryzae]	391.0	[0..91]	[957..204]
gi\|39944902, gi\|... - gi\|39944902\|ref\|XP_361988.1\| hypothetical protein MGG_04433 [Magnaporthe grisea 70-15], gb\|EAA50674....	381.0	[0..85]	[957..224]
gi\|13625941, gi\|... - gi\|162464404\|ref\|NP_001105050.1\| sulfate transporter ST1 [Zea mays], gi\|13625941\|gb\|AAK35215.1\|AF355...	371.0	[0..79]	[736..5]
gi\|24421087 - gi\|24421087\|emb\|CAD55701.1\| sulphate transporter [Triticum aestivum]	369.0	[0..79]	[729..4]
gi\|66849221, gi\|... - gi\|70993480\|ref\|XP_751587.1\| sulfate transporter family protein [Aspergillus fumigatus Af293], gi\|66... gi\|159125486 - gi\|159125486\|gb\|EDP50603.1\| sulfate transporter family protein [Aspergillus fumigatus A1163]	362.0	[0..88]	[951..150]
gi\|28300414, gi\|... - gi\|28300414\|gb\|AAO34714.1\| high-affinity sulfate transporter HvST1 [Hordeum vulgare subsp. vulgare],...	362.0	[0..79]	[731..4]

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Predicted Domain #1

Region A:
Residues: [1-141]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTHSLNQKR SLLYPSIDNG SVPDSSFLSQ SFRDTNDIHL LSARLASVEV DPETLPSNSP  60
   61 ETNDDVSNYD YMSISSYQRA HSLASTSRND FNYRPSEINE TRPLLPEREE HSSQLPPAQN 120
  121 QVLPFQSLNA PSKKLRGRIS L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.69897
Match:	1hynP
Description:	Erythrocite membrane Band 3
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [142-519]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKIYQFFFDD KGPILFILNI PAVIIGLLLN ILDALSYGLI LFPISDPLFK NLGADGLAIY  60
   61 YVSCVVSQLV YSLGGSFFKG SVGSEMIEVI PFFHQIAFTI LNRVGEDNPK SVIATTILAY 120
  121 CLSSILTGLV FFILGILRLG RLIEFFPRHI LLGCIGGVGS FLVLTAVEVS SRLEGSVSFN 180
  181 WASLSALFQP MTFAKWSIPL FLSSALEFAQ QRWPHPFLIP SFFVIAPAIF YVLVWAIPGM 240
  241 SLEYLRETGW VFSSTETNVP WYHFYSLFSL RDTDWSALLA TVPEMCALTF FGILHVPINV 300
  301 PALAISLGLD FVDTDKELIA HGVSNTLSGA VGSIQNYMTY TNSLMFIRSG GNNRLAGIML 360
  361 ALATVALLVI GPGIIAYI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.0
Match:	1qcrC
Description:	Mitochondrial cytochrome b subunit, C-terminal domain; Mitochondrial cytochrome b subunit, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ubiquinol-cytochrome-c reductase activity	1.84397718479397	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	1.84397718479397	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors	1.46506661289025	bayes_pls_golite062009
oxidoreductase activity	1.04489900181563	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	1.01648249832407	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.96543059681604	bayes_pls_golite062009
cation transmembrane transporter activity	0.93489728358628	bayes_pls_golite062009
ion transmembrane transporter activity	0.90519924080591	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.828564353399269	bayes_pls_golite062009
electron carrier activity	0.795356798782267	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.79008311732545	bayes_pls_golite062009
transmembrane transporter activity	0.76908331657866	bayes_pls_golite062009
transporter activity	0.75734453197391	bayes_pls_golite062009
substrate-specific transporter activity	0.74459953925375	bayes_pls_golite062009
catalytic activity	0.292921973619001	bayes_pls_golite062009
binding	0.014145172910173	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [520-601]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVWTVGCLIY LLGIELLKES LWDPIGITTK IEYFTICAIV FTMTVVDFVV GIVIGIIMAC  60
   61 VFFVIQASSR SALRGIYSGG IV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [602-727]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSTVRRPMNQ QRFLNEIGRQ IQVCKLSGFL FFGTINGVEK NIAGLIEELN VSNNPLRFLI  60
   61 IDFSLVNGAD FSVVQAFLRI RRMLATMNVQ LCVCGLDETR SSFKTLTTMC FGGDDNCGCQ 120
  121 VFEDVN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.09691
Match:	1sboA
Description:	Solution Structure of putative anti sigma factor antagonist from Thermotoga maritima (TM1442)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.07653468396849	bayes_pls_golite062009
protein binding	0.597573611851393	bayes_pls_golite062009

Predicted Domain #5

Region A:
Residues: [728-958]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSLEYCENML LDDYDVYRTK LLHKAGYSHT LAVPGKHKQN ISMAETFSPS PRHDLLRQVA  60
   61 MSSVKAETKE LSKFEKYAKY EQPFPLLMQV FGEITTKRED FWLGLCPFFK KAFLRKGDLL 120
  121 WRKGDTPSKL VILETGMVKA SYQMDRESLS ENITCLCVVG ELPFFSKTCY NATVVAELDS 180
  181 AVWILDREGW ETMLKSSDKA EVIENEMLYL TLKMTRDKFN VFTNFALNLY R

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.0
Match:	1q3eA
Description:	HCN2J 443-645 in the presence of cGMP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
channel activity	0.9948983230902	bayes_pls_golite062009
passive transmembrane transporter activity	0.9948983230902	bayes_pls_golite062009
ion channel activity	0.98755773817668	bayes_pls_golite062009
substrate-specific channel activity	0.987458104759969	bayes_pls_golite062009
gated channel activity	0.78371914338887	bayes_pls_golite062009
ion transmembrane transporter activity	0.7684791403927	bayes_pls_golite062009
cation channel activity	0.7233798223572	bayes_pls_golite062009
ligand-gated ion channel activity	0.70844158731597	bayes_pls_golite062009
ligand-gated channel activity	0.70844158731597	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.6504618496083	bayes_pls_golite062009
transmembrane transporter activity	0.62176462883745	bayes_pls_golite062009
transporter activity	0.60710287780621	bayes_pls_golite062009
substrate-specific transporter activity	0.60224718938208	bayes_pls_golite062009
cation transmembrane transporter activity	0.49512775442004	bayes_pls_golite062009
binding	0.447920938568048	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.35806938795889	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions:

Predicted functions: