YRC Public Data Repository - Protein Structure Prediction

Protein:	SYFB_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	589 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SYFB_SCHPO.

Description	E-value	Query Range	Subject Range
SYFB_SHIFL - Phenylalanine--tRNA ligase beta subunit OS=Shigella flexneri GN=pheT PE=3 SV=1 gi\|110615025, gi... - gi\|110805477\|ref\|YP_688997.1\| phenylalanyl-tRNA synthetase subunit beta [Shigella flexneri 5 str. 84... gi\|24112891, gi\|... - gi\|24112891\|ref\|NP_707401.1\| phenylalanyl-tRNA synthetase subunit beta [Shigella flexneri 2a str. 30... gi\|30063020, gi\|... - gi\|30063020\|ref\|NP_837191.1\| phenylalanyl-tRNA synthetase subunit beta [Shigella flexneri 2a str. 24...	536.0	[0..3]	[588..104]
gi\|83586016, gi\|... - gi\|83586016\|ref\|ZP_00924654.1\| COG0072: Phenylalanyl-tRNA synthetase beta subunit [Escherichia coli ... EG10710 - phenylalanine tRNA synthetase, beta subunit / Phenylalanine--tRNA ligase, beta-subunit gi\|157066854, gi... - gi\|75195786\|ref\|ZP_00705856.1\| COG0072: Phenylalanyl-tRNA synthetase beta subunit [Escherichia coli ... SYFB_ECOLI - Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (Phenylalanine--tRNA ligase beta chain) (PheRS... gi\|170019937, gi... - gi\|170019937\|ref\|YP_001724891.1\| phenylalanyl-tRNA synthetase subunit beta [Escherichia coli ATCC 87... gi\|170081372, gi... - gi\|170081372\|ref\|YP_001730692.1\| phenylalanine tRNA synthetase, beta subunit [Escherichia coli str. ... gi\|124498960, gi... - gi\|124530857\|ref\|ZP_01701362.1\| phenylalanyl-tRNA synthetase, beta subunit [Escherichia coli B], gi\|... gi\|238862020, gi... - gi\|238900928\|ref\|YP_002926724.1\| phenylalanine tRNA synthetase, beta subunit [Escherichia coli BW295... gi\|251785163, gi... - gi\|251785163\|ref\|YP_002999467.1\| hypothetical protein B21_01671 [Escherichia coli BL21], gi\|24237743... gi\|253324376, gi... - gi\|254288561\|ref\|YP_003054309.1\| phenylalanyl-tRNA synthetase beta subunit [Escherichia coli BL21(DE... gi\|253973674, gi... - gi\|254161773\|ref\|YP_003044881.1\| phenylalanyl-tRNA synthetase beta subunit [Escherichia coli B str. ... EG10710 - phenylalanine tRNA synthetase, beta subunit / Phenylalanine--tRNA ligase, beta-subunit gi\|1742793, gi\|8... - gi\|89108553\|ref\|AP_002333.1\| phenylalanine tRNA synthetase, beta subunit [Escherichia coli str. K-12...	535.0	[0..3]	[588..104]
gi\|195937397 - gi\|195937397\|ref\|ZP_03082779.1\| phenylalanyl-tRNA synthetase subunit beta [Escherichia coli O157:H7 ... gi\|189377559, gi... - gi\|189377559\|gb\|EDU95975.1\| phenylalanyl-tRNA synthetase, beta-subunit [Escherichia coli O157:H7 str... gi\|208730857, gi... - gi\|208816514\|ref\|ZP_03257634.1\| phenylalanyl-tRNA synthetase, beta-subunit [Escherichia coli O157:H7... gi\|208725241, gi... - gi\|208810725\|ref\|ZP_03252601.1\| phenylalanyl-tRNA synthetase, beta-subunit [Escherichia coli O157:H7... gi\|168774986, gi... - gi\|187769368\|gb\|EDU33212.1\| phenylalanyl-tRNA synthetase, beta-subunit [Escherichia coli O157:H7 str... SYFB_ECO57 - Phenylalanine--tRNA ligase beta subunit OS=Escherichia coli O157:H7 GN=pheT PE=3 SV=1 gi\|189360628, gi... - gi\|189360628\|gb\|EDU79047.1\| phenylalanyl-tRNA synthetase, beta-subunit [Escherichia coli O157:H7 str... gi\|168788109, gi... - gi\|189371944\|gb\|EDU90360.1\| phenylalanyl-tRNA synthetase, beta-subunit [Escherichia coli O157:H7 str... gi\|189000347, gi... - gi\|189000347\|gb\|EDU69333.1\| phenylalanyl-tRNA synthetase, beta-subunit [Escherichia coli O157:H7 str... gi\|188016222, gi... - gi\|188016222\|gb\|EDU54344.1\| phenylalanyl-tRNA synthetase, beta-subunit [Escherichia coli O157:H7 str... gi\|13361887, gi\|... - gi\|15831674\|ref\|NP_310447.1\| phenylalanyl-tRNA synthetase subunit beta [Escherichia coli O157:H7 str... gi\|189367519, gi... - gi\|189367519\|gb\|EDU85935.1\| phenylalanyl-tRNA synthetase, beta-subunit [Escherichia coli O157:H7 str... gi\|168756714, gi... - gi\|189356209\|gb\|EDU74628.1\| phenylalanyl-tRNA synthetase, beta-subunit [Escherichia coli O157:H7 str... gi\|209768888, gi... - pir\|\|H85779 phenylalanine tRNA synthetase, beta-subunit [imported] - Escherichia coli (strain O157:H... gi\|15802125, gi\|... - gi\|15802125\|ref\|NP_288147.1\| phenylalanyl-tRNA synthetase subunit beta [Escherichia coli O157:H7 EDL... gi\|254592730, gi... - gi\|254793330\|ref\|YP_003078167.1\| phenylalanine tRNA synthetase, beta subunit [Escherichia coli O157:... gi\|209161311, gi... - gi\|209399911\|ref\|YP_002270783.1\| phenylalanyl-tRNA synthetase, beta-subunit [Escherichia coli O157:H... gi\|208818689, gi... - gi\|208818689\|ref\|ZP_03259009.1\| phenylalanyl-tRNA synthetase, beta-subunit [Escherichia coli O157:H7... gi\|217318326, gi... - gi\|217328979\|ref\|ZP_03445060.1\| phenylalanyl-tRNA synthetase, beta-subunit [Escherichia coli O157:H7...	535.0	[0..3]	[588..104]
SYFB_SHISS - Phenylalanine--tRNA ligase beta subunit OS=Shigella sonnei (strain Ss046) GN=pheT PE=3 SV=1 gi\|218352007, gi... - gi\|218695275\|ref\|YP_002402942.1\| phenylalanyl-tRNA synthetase subunit beta [Escherichia coli 55989],... gi\|157080624, gi... - gi\|75190750\|ref\|ZP_00704017.1\| COG0072: Phenylalanyl-tRNA synthetase beta subunit [Escherichia coli ...	534.0	[0..3]	[588..104]
gi\|188491937, gi... - gi\|75513787\|ref\|ZP_00736163.1\| COG0072: Phenylalanyl-tRNA synthetase beta subunit [Escherichia coli ...	534.0	[0..3]	[588..104]
gi\|75236815, gi\|... - gi\|75236815\|ref\|ZP_00720886.1\| COG0072: Phenylalanyl-tRNA synthetase beta subunit [Escherichia coli ...	534.0	[0..3]	[588..104]
gi\|218689658, gi... - gi\|218689658\|ref\|YP_002397870.1\| phenylalanyl-tRNA synthetase subunit beta [Escherichia coli ED1a], ... gi\|190908004, gi... - gi\|75241408\|ref\|ZP_00725259.1\| COG0072: Phenylalanyl-tRNA synthetase beta subunit [Escherichia coli ... gi\|110641835, gi... - gi\|110641835\|ref\|YP_669565.1\| phenylalanyl-tRNA synthetase subunit beta [Escherichia coli 536], gi\|1...	534.0	[0..3]	[588..104]
SYFB_ECOL6 - Phenylalanine--tRNA ligase beta chain OS=Escherichia coli O6 GN=pheT PE=3 SV=1 SYFB_ECOL6 - Phenylalanine--tRNA ligase beta subunit OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPE... gi\|227885865, gi... - gi\|227885865\|ref\|ZP_04003670.1\| Phenylalanyl-tRNA synthetase beta chain [Escherichia coli 83972], gi...	534.0	[0..3]	[588..104]
gi\|75228976, gi\|... - gi\|75228976\|ref\|ZP_00715563.1\| COG0072: Phenylalanyl-tRNA synthetase beta subunit [Escherichia coli ...	534.0	[0..3]	[588..104]
gi\|187427762, gi... - gi\|75177358\|ref\|ZP_00697447.1\| COG0072: Phenylalanyl-tRNA synthetase beta subunit [Shigella boydii B... SYFB_SHIBS - Phenylalanine--tRNA ligase beta subunit OS=Shigella boydii serotype 4 (strain Sb227) GN=pheT PE=3 SV...	533.0	[0..3]	[588..104]

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Predicted Domain #1

Region A:
Residues: [1-148]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTISCDKEE LYKALGREYT TQEFDELCFQ FGIELDEDTT NDPERSPSER PSLKIDIPAN  60
   61 RYDMLCLEGI AQALNVFNRR MATPQYKLLP STTSLTISPE TSEIRPYAAA AILRGVKLDP 120
  121 IRYQSFIALQ DKLHANLCRN RTLVAIGT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	72.0
Match:	2cxiA
Description:	No description for 2cxiA was found.

Predicted Domain #2

Region A:
Residues: [149-521]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HDFSVMEGPF TYEALKPEEI NFVPLNQTQE INGSNLLEFY KDSKHLSRYL HIIANSPRYP  60
   61 VILDAKRRVC SLPPIINSEF SKISVDTRDI FIDVTATDKT KLEIVVNMMT TMFSCYCEEP 120
  121 FTIEPVNIIS EHNGCTRVTP NLNPTCFKAD IDYLNEACGL SLPEDEICHL LTRMMLTAKP 180
  181 NPNDSKTLLV YVPPLRADIL HQCDIMEDLG IAYGYDNLKH TYPAHSVTFG KPFEVNRLAD 240
  241 IIRNEVAYAG WSEVMPFILC SHDENYAWLR KTDDSKAVQL ANPKTLEFQV VRSSLLPGIL 300
  301 KTVRENKNHA LPIKIFEVSD VAFCDYSRER MTRNERHLCA IFAGLNSGFE QIHGLLDRVM 360
  361 LMLNTKRIMN PKD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.045757
Match:	1nyqA
Description:	Structure of Staphylococcus aureus threonyl-tRNA synthetase complexed with an analogue of threonyl adenylate
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phenylalanine-tRNA ligase activity	13.8919118344182	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	12.5698315343202	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	12.5698315343202	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	12.5592545638101	bayes_pls_golite062009
ligase activity	6.92073480193262	bayes_pls_golite062009
glycine-tRNA ligase activity	2.61548498770105	bayes_pls_golite062009
threonine-tRNA ligase activity	2.18642354927	bayes_pls_golite062009
serine-tRNA ligase activity	2.07594942154162	bayes_pls_golite062009
catalytic activity	1.99372273395202	bayes_pls_golite062009
alanine-tRNA ligase activity	1.82594054955281	bayes_pls_golite062009
lysine-tRNA ligase activity	1.72324031407565	bayes_pls_golite062009
histidine-tRNA ligase activity	1.72215103383322	bayes_pls_golite062009
transcription regulator activity	0.973820663472435	bayes_pls_golite062009
binding	0.951197041515827	bayes_pls_golite062009
asparagine-tRNA ligase activity	0.921492123574877	bayes_pls_golite062009
nucleic acid binding	0.864670700044417	bayes_pls_golite062009
DNA binding	0.621789297870471	bayes_pls_golite062009
transcription factor activity	0.265631643816467	bayes_pls_golite062009
aspartate-tRNA ligase activity	0.00572514744734753	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [522-589]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDAVGYWIEA EDDSTFFPGR CAAVYYRKDF GTAGIRVGVF GVLHPLVLEK FELTSAASAV  60
   61 EIDLTLWV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.39794
Match:	1b70A
Description:	Phenyl-tRNA synthetase (PheRS) alpha subunit, PheS
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: