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View Structure Prediction Details

Protein: gi|61356498, gi|...
Organism: synthetic construct
Length: 185 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|61356498, gi|....

Description E-value Query
Range
Subject
Range
gi|61356510 - gi|61356510|gb|AAX41253.1| dual specificity phosphatase 3 [synthetic construct]
1.0E-42 [1..185] [1..185]
gi|1633322, gi|1... - gi|1633322|pdb|1VHR|B Chain B, Human Vh1-Related Dual-Specificity Phosphatase, gi|1633321|pdb|1VHR|A...
3.0E-42 [2..185] [1..184]
gi|73965594 - gi|73965594|ref|XP_537624.2| PREDICTED: similar to Dual specificity protein phosphatase 3 (Dual spec...
4.0E-40 [2..184] [45..227]
DUS3_MOUSE - Dual specificity protein phosphatase 3 OS=Mus musculus GN=Dusp3 PE=1 SV=1
6.0E-40 [1..184] [1..184]
gi|109491956, gi... - gi|62657092|ref|XP_573199.1| PREDICTED: similar to Dual specificity protein phosphatase 3 (T-DSP11) ...
1.0E-39 [1..184] [87..270]
IPI00790757, IPI... - Tax_Id=9606 23 kDa protein, IPI:IPI00790757.1|VEGA:OTTHUMP00000181836 Tax_Id=9606 Gene_Symbol=DUSP3 ...
gi|114666937 - gi|114666937|ref|XP_001153398.1| PREDICTED: hypothetical protein LOC468271 isoform 1 [Pan troglodyte...
2.0E-38 [1..185] [1..210]

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Predicted Domain #1
Region A:
Residues: [1-185]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGSFELSVQ DLNDLLSDGS GCYSLPSQPC NEVTPRIYVG NASVAQDIPK LQKLGITHVL  60
   61 NAAEGRSFMH VNTNANFYKD SGITYLGIKA NDTQEFNLSA YFERAADFID QALAQKNGRV 120
  121 LVHCREGYSR SPTLVIAYLM MRQKMDVKSA LSIVRQNREI GPNDGFLAQL CQLNDRLAKE 180
  181 GKLKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.69897
Match: 1vhrA
Description: VH1-related dual-specificity phosphatase, VHR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphoprotein phosphatase activity 7.30669036331612 bayes_pls_golite062009
phosphatase activity 6.6585143972081 bayes_pls_golite062009
phosphoric ester hydrolase activity 6.44546424348532 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 5.70473199778334 bayes_pls_golite062009
protein tyrosine phosphatase activity 5.3097342170423 bayes_pls_golite062009
hydrolase activity 4.08088661270715 bayes_pls_golite062009
transmembrane receptor protein phosphatase activity 2.94635032478625 bayes_pls_golite062009
transmembrane receptor protein tyrosine phosphatase activity 2.94635032478625 bayes_pls_golite062009
protein tyrosine/serine/threonine phosphatase activity 2.77531895423367 bayes_pls_golite062009
protein serine/threonine phosphatase activity 1.95004535887255 bayes_pls_golite062009
binding 1.46731689565365 bayes_pls_golite062009
protein binding 1.2114562222518 bayes_pls_golite062009
inositol or phosphatidylinositol phosphatase activity 1.1200449509328 bayes_pls_golite062009
catalytic activity 1.06283028154109 bayes_pls_golite062009
lipid phosphatase activity 1.05085928819585 bayes_pls_golite062009
non-membrane spanning protein tyrosine phosphatase activity 0.724257798127697 bayes_pls_golite062009
nucleic acid binding 0.438873526795276 bayes_pls_golite062009
protein kinase activity 0.271008536688339 bayes_pls_golite062009
DNA binding 0.168641341125007 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.0776644624761281 bayes_pls_golite062009
kinase activity 0.0715870881653981 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.0361995996259996 bayes_pls_golite062009

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