YRC Public Data Repository - Protein Structure Prediction

Protein:	HSLU_SHISS
Organism:	Shigella sonnei Ss046
Length:	443 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HSLU_SHISS.

Description	E-value	Query Range	Subject Range
gi\|238726266, gi... - gi\|77977397\|ref\|ZP_00832847.1\| COG1220: ATP-dependent protease HslVU (ClpYQ), ATPase subunit [Yersin...	372.0	[0..1]	[443..1]
gi\|238789597, gi... - gi\|77972978\|ref\|ZP_00828532.1\| COG1220: ATP-dependent protease HslVU (ClpYQ), ATPase subunit [Yersin...	371.0	[0..1]	[443..1]
gi\|238786105, gi... - gi\|77957389\|ref\|ZP_00821446.1\| COG1220: ATP-dependent protease HslVU (ClpYQ), ATPase subunit [Yersin... gi\|238717841, gi... - gi\|77961039\|ref\|ZP_00824887.1\| COG1220: ATP-dependent protease HslVU (ClpYQ), ATPase subunit [Yersin...	370.0	[0..1]	[443..1]
HSLU_YERPN - ATP-dependent protease ATPase subunit HslU OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=hslU ... gi\|165936245, gi... - gi\|89105845\|ref\|ZP_01178358.1\| COG1220: ATP-dependent protease HslVU (ClpYQ), ATPase subunit [Yersin... HSLU_YERPA - ATP-dependent protease ATPase subunit HslU OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=hslU P... gi\|21956973, gi\|... - gi\|22124212\|ref\|NP_667635.1\| ATP-dependent protease ATP-binding subunit [Yersinia pestis KIM], gi\|21... gi\|229836219, gi... - gi\|229836219\|ref\|ZP_04456387.1\| molecular chaperone and ATPase component of HslUV protease [Yersinia... HSLU_YERPS - ATP-dependent protease ATPase subunit HslU OS=Yersinia pseudotuberculosis serotype I (strain IP32953... gi\|229839958, gi... - gi\|229839958\|ref\|ZP_04460117.1\| molecular chaperone and ATPase component of HslUV protease [Yersinia... gi\|45434825, gi\|... - gi\|45439970\|ref\|NP_991509.1\| ATP-dependent protease ATP-binding subunit [Yersinia pestis biovar Micr... gi\|229690350, gi... - gi\|229842040\|ref\|ZP_04462195.1\| molecular chaperone and ATPase component of HslUV protease [Yersinia... gi\|16120452, gi\|... - gi\|218927320\|ref\|YP_002345195.1\| ATP-dependent protease ATP-binding subunit HslU [Yersinia pestis CO... gi\|166011445, gi... - gi\|166011445\|ref\|ZP_02232343.1\| heat shock protein HslVU, ATPase subunit HslU [Yersinia pestis biova... gi\|165919578, gi... - gi\|165928396\|ref\|ZP_02224228.1\| heat shock protein HslVU, ATPase subunit HslU [Yersinia pestis biova... gi\|167048119, gi... - gi\|167402503\|ref\|ZP_02307957.1\| heat shock protein HslVU, ATPase subunit HslU [Yersinia pestis biova... HSLU_YERPE - ATP-dependent protease ATPase subunit HslU OS=Yersinia pestis GN=hslU PE=3 SV=1 gi\|166213726, gi... - gi\|166213726\|ref\|ZP_02239761.1\| heat shock protein HslVU, ATPase subunit HslU [Yersinia pestis biova... gi\|167055039, gi... - gi\|167425891\|ref\|ZP_02317644.1\| heat shock protein HslVU, ATPase subunit HslU [Yersinia pestis biova... gi\|167419213, gi... - gi\|167419213\|ref\|ZP_02310966.1\| heat shock protein HslVU, ATPase subunit HslU [Yersinia pestis biova... HSLU_YERPB - ATP-dependent protease ATPase subunit HslU OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+)... HSLU_YERPY - ATP-dependent protease ATPase subunit HslU OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII... HSLU_YERPG - ATP-dependent protease ATPase subunit HslU OS=Yersinia pestis bv. Antiqua (strain Angola) GN=hslU PE... HSLU_YERP3 - ATP-dependent protease ATPase subunit HslU OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 3... gi\|150260792, gi... - gi\|150260792\|ref\|ZP_01917520.1\| ATP-binding heat shock protein [Yersinia pestis CA88-4125], gi\|14929... HSLU_YERPP - ATP-dependent protease ATPase subunit HslU OS=Yersinia pestis (strain Pestoides F) GN=hslU PE=3 SV=1 HSLU_YERPS - ATP-dependent protease ATPase subunit HslU OS=Yersinia pseudotuberculosis GN=hslU PE=3 SV=1	369.0	[0..1]	[443..1]
HSLU_ERWCT - ATP-dependent protease ATPase subunit HslU OS=Erwinia carotovora subsp. atroseptica GN=hslU PE=3 SV=... HSLU_PECAS - ATP-dependent protease ATPase subunit HslU OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC B...	367.0	[0..1]	[443..1]
gi\|227885327, gi... - gi\|227885327\|ref\|ZP_04003132.1\| ATP-dependent protease ATP-binding subunit [Escherichia coli 83972],... gi\|226902901, gi... - gi\|237702964\|ref\|ZP_04533445.1\| ATP-dependent protease ATP-binding subunit [Escherichia sp. 3_2_53FA... HSLU_ECOK1 - ATP-dependent protease ATPase subunit HslU OS=Escherichia coli O1:K1 / APEC GN=hslU PE=3 SV=1 HSLU_ECOL6 - ATP-dependent protease ATPase subunit HslU OS=Escherichia coli O6 GN=hslU PE=2 SV=1 HSLU_ECOL6 - ATP-dependent protease ATPase subunit HslU OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / ... HSLU_ECOL5 - ATP-dependent protease ATPase subunit HslU OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=hsl... HSLU_ECO27 - ATP-dependent protease ATPase subunit HslU OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=h... sp\|B7UNQ1\|HSLU_ECO27 - ATP-dependent protease ATPase subunit HslU OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=h... HSLU_ECOUT - ATP-dependent protease ATPase subunit HslU OS=Escherichia coli (strain UTI89 / UPEC) GN=hslU PE=3 SV... HSLU_ECOSM - ATP-dependent protease ATPase subunit HslU OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=hslU PE=3... gi\|190907027, gi... - gi\|75240324\|ref\|ZP_00724264.1\| COG1220: ATP-dependent protease HslVU (ClpYQ), ATPase subunit [Escher... HSLU_ECO81 - ATP-dependent protease ATPase subunit HslU OS=Escherichia coli O81 (strain ED1a) GN=hslU PE=3 SV=1 HSLU_ECO45 - ATP-dependent protease ATPase subunit HslU OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=hslU P... HSLU_ECOLU - ATP-dependent protease ATPase subunit HslU OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) G... HSLU_ECO7I - ATP-dependent protease ATPase subunit HslU OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=hslU ...	367.0	[0..1]	[443..1]
gi\|193063956, gi... - gi\|75258086\|ref\|ZP_00729547.1\| COG1220: ATP-dependent protease HslVU (ClpYQ), ATPase subunit [Escher... gi\|75230452, gi\|... - gi\|75230452\|ref\|ZP_00716938.1\| COG1220: ATP-dependent protease HslVU (ClpYQ), ATPase subunit [Escher... gi\|194427514, gi... - gi\|75211255\|ref\|ZP_00711354.1\| COG1220: ATP-dependent protease HslVU (ClpYQ), ATPase subunit [Escher... HSLU_ECO24 - ATP-dependent protease ATPase subunit HslU OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=h... HSLU_ECO8A - ATP-dependent protease ATPase subunit HslU OS=Escherichia coli O8 (strain IAI1) GN=hslU PE=3 SV=1 HSLU_ECO55 - ATP-dependent protease ATPase subunit HslU OS=Escherichia coli (strain 55989 / EAEC) GN=hslU PE=3 SV... HSLU_ECOSE - ATP-dependent protease ATPase subunit HslU OS=Escherichia coli (strain SE11) GN=hslU PE=3 SV=1	366.0	[0..1]	[443..1]
HSLU_SODGM - ATP-dependent protease ATPase subunit HslU OS=Sodalis glossinidius (strain morsitans) GN=hslU PE=3 S...	366.0	[0..1]	[443..1]
HSLU_SHIB3 - ATP-dependent protease ATPase subunit HslU OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS51...	365.0	[0..1]	[443..1]
gi\|7245738, gi\|7... - gi\|7245738\|pdb\|1DO0\|F Chain F, Orthorhombic Crystal Form Of Heat Shock Locus U (Hslu) From Escherich...	364.0	[0..2]	[443..1]

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Predicted Domain #1

Region A:
Residues: [1-443]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEMTPREIV SELDKHIIGQ DNAKRSVAIA LRNRWRRMQL NEELRHEVTP KNILMIGPTG  60
   61 VGKTEIARRL AKLANAPFIK VEATKFTEVG YVGKEVDSII RDLTDAAVKM VRVQAIEKNR 120
  121 YRAEELAEER ILDVLIPPAK NNWGQTEQQQ EPSAARQAFR KKLREGQLDD KEIEIDLAAA 180
  181 PMGVEIMAPP GMEEMTSQLQ SMFQNLGGQK QKARKLKIKD AMKLLIEEEA AKLVNPEELK 240
  241 QDAIDAVEQH GIVFIDEIDK ICKRGESSGP DVSREGVQRD LLPLVEGCTV STKHGMVKTD 300
  301 HILFIASGAF QIAKPSDLIP ELQGRLPIRV ELQALTTSDF ERILTEPNAS ITVQYKALMA 360
  361 TEGVNIEFTD SGIKRIAEAA WQVNESTENI GARRLHTVLE RLMEEISYDA SDLSGQNITI 420
  421 DADYVSKHLD ALVADEDLSR FIL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	102.0
Match:	1g4aE
Description:	HslU
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	2.55157966585974	bayes_pls_golite062009
binding	1.31163400557981	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.546796591575762	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.543610140926125	bayes_pls_golite062009
pyrophosphatase activity	0.540750418412449	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.517457589081898	bayes_pls_golite062009
purine nucleotide binding	0.428373955572763	bayes_pls_golite062009
purine ribonucleotide binding	0.424644011903671	bayes_pls_golite062009
ribonucleotide binding	0.424583288440993	bayes_pls_golite062009
nucleotide binding	0.422354428195324	bayes_pls_golite062009
ATP binding	0.04834397972685	bayes_pls_golite062009
adenyl ribonucleotide binding	0.0149501427627318	bayes_pls_golite062009
adenyl nucleotide binding	0.00365326483311895	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: