YRC Public Data Repository - Protein Structure Prediction

Protein:	SYQ_ECOHS
Organism:	Escherichia coli HS
Length:	554 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SYQ_ECOHS.

Description	E-value	Query Range	Subject Range
gi\|254791832, gi... - gi\|254791832\|ref\|YP_003076669.1\| glutamyl-tRNA synthetase [Escherichia coli O157:H7 str. TW14359], g... gi\|209776782, gi... - pir\|\|F85567 glutamine tRNA synthetase [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|15800382, gi\|... - gi\|15800382\|ref\|NP_286394.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 EDL933], gi\|125135... SYQ_ECO57 - Glutamine--tRNA ligase OS=Escherichia coli O157:H7 GN=glnS PE=3 SV=3 gi\|15829964, gi\|... - gi\|15829964\|ref\|NP_308737.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. Sakai], gi\|13... gi\|217322449, gi... - gi\|217326228\|ref\|ZP_03442312.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. TW14588], ... gi\|195939405 - gi\|195939405\|ref\|ZP_03084787.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4024] gi\|208727466, gi... - gi\|208807665\|ref\|ZP_03250002.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4206], g... gi\|208815888, gi... - gi\|208815888\|ref\|ZP_03257067.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4045], g... SYQ_ECO5E - Glutamine--tRNA ligase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=glnS PE=3 SV=1 gi\|189363598, gi... - gi\|189363598\|gb\|EDU82017.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4486], gi\|16... gi\|187766947, gi... - gi\|187766947\|gb\|EDU30791.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4196], gi\|16... gi\|168779164, gi... - gi\|189002717\|gb\|EDU71703.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4076], gi\|16... gi\|189373642, gi... - gi\|189373642\|gb\|EDU92058.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. EC869], gi\|168... gi\|188013596, gi... - gi\|188013596\|gb\|EDU51718.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4113], gi\|16...	682.0	[0..1]	[554..1]
SYQ_ECOK1 - Glutamine--tRNA ligase OS=Escherichia coli O1:K1 / APEC GN=glnS PE=3 SV=1 SYQ_ECOL6 - Glutamine--tRNA ligase OS=Escherichia coli O6 GN=glnS PE=3 SV=3 gi\|227838431, gi... - gi\|227884345\|ref\|ZP_04002150.1\| glutaminyl-tRNA synthetase [Escherichia coli 83972], gi\|227838431\|gb... gi\|226898562, gi... - gi\|237707352\|ref\|ZP_04537833.1\| glutaminyl-tRNA synthetase [Escherichia sp. 3_2_53FAA], gi\|226898562... SYQ_ECOL6 - Glutamine--tRNA ligase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=glnS PE=3 S... gi\|75237569, gi\|... - gi\|75237569\|ref\|ZP_00721600.1\| COG0008: Glutamyl- and glutaminyl-tRNA synthetases [Escherichia coli ... SYQ_ECOUT - Glutamine--tRNA ligase OS=Escherichia coli (strain UTI89 / UPEC) GN=glnS PE=3 SV=1 SYQ_ECO27 - Glutamine--tRNA ligase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=glnS PE=3 SV=1 sp\|B7UKW1\|SYQ_ECO27 - Glutaminyl-tRNA synthetase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=glnS PE=3 SV=1 SYQ_ECOL5 - Glutamine--tRNA ligase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=glnS PE=3 SV=1 SYQ_ECO45 - Glutamine--tRNA ligase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=glnS PE=3 SV=1 SYQ_ECO81 - Glutamine--tRNA ligase OS=Escherichia coli O81 (strain ED1a) GN=glnS PE=3 SV=1	682.0	[0..1]	[554..1]
gi\|192954959, gi... - gi\|75214656\|ref\|ZP_00713173.1\| COG0008: Glutamyl- and glutaminyl-tRNA synthetases [Escherichia coli ...	681.0	[0..1]	[554..1]
gi\|190900609, gi... - gi\|75227334\|ref\|ZP_00714117.1\| COG0008: Glutamyl- and glutaminyl-tRNA synthetases [Escherichia coli ...	681.0	[0..1]	[554..1]
SYQ_SHIBS - Glutamine--tRNA ligase OS=Shigella boydii serotype 4 (strain Sb227) GN=glnS PE=3 SV=1	681.0	[0..1]	[554..1]
gi\|90580037, gi\|... - gi\|90580037\|ref\|ZP_01235845.1\| glutaminyl-tRNA synthetase [Vibrio angustum S14], gi\|90438922\|gb\|EAS6...	680.0	[0..1]	[554..1]
gi\|194417305, gi... - gi\|83569130\|ref\|ZP_00920590.1\| COG0008: Glutamyl- and glutaminyl-tRNA synthetases [Shigella dysenter...	680.0	[0..1]	[554..1]
SYQ_SHIDS - Glutamine--tRNA ligase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=glnS PE=3 SV=1	680.0	[0..1]	[554..1]
gi\|75511080, gi\|... - gi\|75511080\|ref\|ZP_00733812.1\| COG0008: Glutamyl- and glutaminyl-tRNA synthetases [Escherichia coli ...	680.0	[0..1]	[554..1]
SYQ_SHIB3 - Glutamine--tRNA ligase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=glnS PE=3 SV=1	680.0	[0..1]	[554..1]

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Predicted Domain #1

Region A:
Residues: [1-554]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEAEARPTN FIRQIIDEDL ASGKHTTVHT RFPPEPNGYL HIGHAKSICL NFGIAQDYKG  60
   61 QCNLRFDDTN PVKEDIEYVE SIKNDVEWLG FHWSGNVRYS SDYFDQLHAY AIELINKGLA 120
  121 YVDELTPEQI REYRGTLTQP GKNSPYRDRS VEENLALFEK MRAGGFEEGK ACLRAKIDMA 180
  181 SPFIVMRDPV LYRIKFAEHH QTGNKWCIYP MYDFTHCISD ALEGITHSLC TLEFQDNRRL 240
  241 YDWVLDNITI PVHPRQYEFS RLNLEYTVMS KRKLNLLVTD KHVEGWDDPR MPTISGLRRR 300
  301 GYTAASIREF CKRIGVTKQD NTIEMASLES CIREDLNENA PRAMAVIDPV KLVIENYQGE 360
  361 GEMVTMPNHP NKPEMGSRQV PFSGEIWIDR ADFREEANKQ YKRLVLGKEV RLRNAYVIKA 420
  421 ERVEKDAEGN ITTIFCTYDA DTLSKDPADG RKVKGVIHWV SAAHALPVEI RLYDRLFSVP 480
  481 NPGAADDFLS VINPESLVIK QGFAEPSLKD AVAGKAFQFE REGYFCLDSR HSTAEKPVFN 540
  541 RTVGLRDTWA KVGE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1o0bA
Description:	Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain; Glutaminyl-tRNA synthetase (GlnRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming aminoacyl-tRNA and related compounds	7.16276509815667	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	7.16276509815667	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.13957775963187	bayes_pls_golite062009
ligase activity	6.11211476973434	bayes_pls_golite062009
glutamine-tRNA ligase activity	4.45248364270113	bayes_pls_golite062009
structural constituent of ribosome	3.84987020398591	bayes_pls_golite062009
structural molecule activity	3.52958514226509	bayes_pls_golite062009
glutamate-tRNA ligase activity	2.63681738794687	bayes_pls_golite062009
catalytic activity	2.37674226834122	bayes_pls_golite062009
methionine-tRNA ligase activity	2.01261843164558	bayes_pls_golite062009
5S rRNA binding	1.92764054805963	bayes_pls_golite062009
tyrosine-tRNA ligase activity	1.88984817882585	bayes_pls_golite062009
rRNA binding	1.48338599637907	bayes_pls_golite062009
tryptophan-tRNA ligase activity	1.14187887833901	bayes_pls_golite062009
arginine-tRNA ligase activity	1.13743634264647	bayes_pls_golite062009
cysteine-tRNA ligase activity	0.844943947059557	bayes_pls_golite062009
nucleotidyltransferase activity	0.2293846471193	bayes_pls_golite062009
nucleic acid binding	0.161799496958314	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.126511747475258	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: