YRC Public Data Repository - Protein Structure Prediction

Protein:	YHDD_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	618 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YHDD_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|67536776, gi\|... - gi\|67536776\|ref\|XP_662162.1\| hypothetical protein AN4558.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	244.0	[0..1]	[614..53]
YCV2_SCHPO - Uncharacterized transcriptional regulatory protein C777.02 OS=Schizosaccharomyces pombe (strain 972 ... SPCC777.02 - transcription factor	237.0	[0..19]	[616..26]
gi\|21913144 - gi\|21913144\|gb\|AAK84946.1\| transcriptional activator Mut3p [Pichia angusta] gi\|134147412 - gi\|134147412\|gb\|ABO63963.1\| transcriptional activator Mut3p [synthetic construct]	237.0	[0..1]	[617..51]
gi\|50549381, gi\|... - gi\|50549381\|ref\|XP_502161.1\| YALI0C22990p [Yarrowia lipolytica], gi\|49648028\|emb\|CAG82481.1\| unnamed... gi\|49648028 - gi\|49648028\|emb\|CAG82481.1\| YALI0C22990p [Yarrowia lipolytica]	237.0	[0..2]	[603..18]
gi\|245224 - gi\|245224\|gb\|AAB21394.1\| NIT4=protein product involved in nitrate assimilation [Neurospora intermedi... NIT4_NEUCR - Nitrogen assimilation transcription factor nit-4 - Neurospora crassa	235.0	[0..7]	[616..41]
NIT4_NEUCR - Nitrogen assimilation transcription factor nit-4 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1... NIT4_NEUCR - Nitrogen assimilation transcription factor nit-4 OS=Neurospora crassa GN=nit-4 PE=4 SV=2	235.0	[0..7]	[616..41]
gi\|50409605, gi\|... - gi\|50409605\|ref\|XP_456889.1\| hypothetical protein DEHA0A13321g [Debaryomyces hansenii CBS767], gi\|49...	234.0	[0..4]	[616..29]
gi\|111056786 - gi\|111056786\|gb\|EAT77906.1\| hypothetical protein SNOG_14714 [Phaeosphaeria nodorum SN15]	233.0	[0..2]	[617..47]

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Predicted Domain #1

Region A:
Residues: [1-148]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQMKPRQDKK NQEIFRISCQ RCRQRKIKCD RLHPCFQCVK SNSQCFYPED PIRRRAPKEY  60
   61 VEALERQIAF FEAFVKKLAK VGSDEQSLMI QDMNNKIVNE GNEYDQTPDI SARKRRKHFR 120
  121 MLPQNNFRYF QFYGTTNVIS ASNLTTTS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.09691
Match:	1d66A
Description:	Gal4; CD2-Gal4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	4.56444258780502	bayes_pls_golite062009
DNA binding	4.26146437716972	bayes_pls_golite062009
nucleic acid binding	4.17369933547911	bayes_pls_golite062009
transcription factor activity	3.049435548132	bayes_pls_golite062009
binding	2.91929847152301	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.03201524223606	bayes_pls_golite062009
sequence-specific DNA binding	1.87955444697212	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	1.86200506906385	bayes_pls_golite062009
transcription activator activity	0.915626626047549	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [149-275]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EIPTFKFPIF SKRKYNDTEN LYEQPFHLEF DTCQELLSLF FLKQYHNFMF VFRDYFIRDF  60
   61 ELGGGPYYSQ WLLFAICSIG AMISPDDDLK NLSNTLANIA EKWVLDEGLN SPDITTLQTL 120
  121 LVLGIRE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [276-350]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGRGLTFKGW LFSGMAFRLV YDMGLHLDPD HWDHSEESRI DREVRRRCFW GCFTLDKLIS  60
   61 LCYGRPPGLY LKQTD

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	33.920819
Match:	PF04082.9
Description:	No description for PF04082.9 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [351-469]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VRNTTQLPYI SELDEPFEIF NKKSELFAAV SAGEDRRGLV QFWLNQVELC KIIHRMLTEV  60
   61 FEDRTSSVLE ASINNIHTEL QKWIADIPME LQWNTRSQKE TSSTVLLLHM LYHSVIIIL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [470-618]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRPSDDNYLK LDNTERYTFE ICWKSAKTIV QLLKIYFKKY DADCLPMTFI HIATSAARII  60
   61 LVKLNENIPE DGDVCNIYLE IITNALDVCA NVWPLASQAS RAILNAYKSC ATSPKENNED 120
  121 SLPLQRSPSL DDVSRFDSLD YIFSPNVKY

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: