YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|56554345, gi\|...
Organism:	Homo sapiens
Length:	134 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|56554345, gi|....

Description	E-value	Query Range	Subject Range
gi\|191126 - gi\|191126\|gb\|AAA36995.1\| 14 kDa beta-galactoside-binding lectin LEG1_CRIGR - Galectin-1 OS=Cricetulus griseus GN=LGALS1 PE=1 SV=2	172.0	[0..1]	[134..2]
gi\|23342428\|emb\|... - unnamed protein product [Rattus sp.] LEG1_RAT - Galectin-1 OS=Rattus norvegicus GN=Lgals1 PE=1 SV=2	170.0	[0..1]	[134..2]
gi\|109149582 - gi\|109149582\|ref\|XP_001083427.1\| PREDICTED: lectin, galactoside-binding, soluble, 1 (galectin 1) iso...	169.0	[0..1]	[134..2]
LEG1_MOUSE - Galectin-1 OS=Mus musculus GN=Lgals1 PE=1 SV=3	169.0	[0..1]	[134..2]
gi\|30584667, gi\|... - gi\|61369162\|gb\|AAX43294.1\| lectin galactoside-binding soluble 1 [synthetic construct], gi\|61369156\|g...	168.0	[0..1]	[134..2]
LGALS1 - lectin, galactoside-binding, soluble, 1 gi\|61358976, gi\|... - gi\|61358983\|gb\|AAX41650.1\| lectin galactoside-binding soluble 1 [synthetic construct], gi\|61358976\|g... HGNC:6561\|MIM:15... - galactoside-binding, soluble, 1 gi\|114686337, gi... - gi\|114686337\|ref\|XP_001162104.1\| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes], gi\|114...	168.0	[0..1]	[134..2]

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Predicted Domain #1

Region A:
Residues: [1-134]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASGLVASNLN LKPGEXLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFN AHGDANTIVC  60
   61 NSKDDGAWGT EQREAVFPFQ PGSVAEVCIT FDQANLTVKL PDGYEFKFPN RLNLEAINYM 120
  121 AADGDFKIKC VAFD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	42.39794
Match:	1gzwA
Description:	X-RAY CRYSTAL STRUCTURE OF HUMAN GALECTIN-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glycosaminoglycan binding	2.70103238455595	bayes_pls_golite062009
binding	2.40096962515027	bayes_pls_golite062009
polysaccharide binding	2.35851723238763	bayes_pls_golite062009
monosaccharide binding	2.09529521879228	bayes_pls_golite062009
carbohydrate binding	1.90829797790335	bayes_pls_golite062009
protein binding	1.80794638640093	bayes_pls_golite062009
heparin binding	1.60966215355794	bayes_pls_golite062009
extracellular matrix binding	1.41229380365824	bayes_pls_golite062009
sugar binding	1.27754120053722	bayes_pls_golite062009
fibronectin binding	1.10309233016451	bayes_pls_golite062009
galactoside binding	1.08479183125487	bayes_pls_golite062009
receptor binding	0.9012250808046	bayes_pls_golite062009
pattern binding	0.83687933614214	bayes_pls_golite062009
extracellular matrix structural constituent	0.5068011550246	bayes_pls_golite062009
transcription regulator activity	0.372701974560119	bayes_pls_golite062009
nucleic acid binding	0.216086300988177	bayes_pls_golite062009
DNA binding	0.157628282318248	bayes_pls_golite062009
growth factor activity	0.119475011376319	bayes_pls_golite062009
fibroblast growth factor 2 binding	0.0714976455077903	bayes_pls_golite062009
fibrinogen binding	0.0714976455077903	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: