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View Structure Prediction Details

Protein: clec-236
Organism: Caenorhabditis elegans
Length: 556 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for clec-236.

Description E-value Query
Range
Subject
Range
gi|76662247 - gi|76662247|ref|XP_598653.2| PREDICTED: similar to mannose receptor, C type 1-like 1 [Bos taurus]
225.0 [0..21] [553..664]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSINSIAAG TITSCWSDVF SKQSRKRSMI LAFILTLLVV PDGTNGMIFS EFLKNYRDLV  60
   61 DISSLKTCWM LGGDGIQQVN PKNEQKGYQC TVKLRAWSTN EKDVKDACMS RIPYYITHAK 120
  121 PENAETSCTF QMNLH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.522879
Match: 1tozA
Description: NMR structure of the human NOTCH-1 ligand binding region
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [136-333]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CDDNYWQIHG RCYRVFDGKY TFEEAQQIKL NILLNDMEGI YDAWVTVPNI KDYFTNGQGE  60
   61 AEVYVQDSAY KYDVRPGSIM MDRLEGRHQV LCEYKPAMTM AEMFYMAKLY SEIYPIHVYT 120
  121 HGAIFTSASY LTVTQRSLIK NTGGPTQYGD EIEKFDTSEL NEKCKLLGNI LNVDSIPMVP 180
  181 TENEQNYVKH LLTDHQFY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.221849
Match: 1bj3A
Description: Snake coagglutinin alpha chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.13629480035749 bayes_pls_golite062009
carbohydrate binding 0.44675717945952 bayes_pls_golite062009
protein binding 0.059857076934361 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [334-405]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSGFKSDGC GRGDYRTQQD GNTSTSFDSI GSNDEYCHAH RNGRYPTMAA MRAPAICAMH  60
   61 EFSWSHGDCD PK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [406-556]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEWAEEMLVY NRTSESVFCH YVDETEKITY YEAKARCNSF GAELTGFDSR DEWVAVSKTL  60
   61 KTCHHWTGGI TKYKSYNVPE IIWDAGVATN TDYFTDVYFQ TTLPDEHLSL LWSEAHVHPT 120
  121 YRNYMYMCTI CGKAAKLVRS EGKVYGLKTT G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.69897
Match: 2h2rA
Description: No description for 2h2rA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle