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View Structure Prediction Details

Protein: clec-236
Organism: Caenorhabditis elegans
Length: 556 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for clec-236.

Description E-value Query
Range
Subject
Range
gi|76662247 - gi|76662247|ref|XP_598653.2| PREDICTED: similar to mannose receptor, C type 1-like 1 [Bos taurus]
225.0 [0..21] [553..664]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSINSIAAG TITSCWSDVF SKQSRKRSMI LAFILTLLVV PDGTNGMIFS EFLKNYRDLV  60
   61 DISSLKTCWM LGGDGIQQVN PKNEQKGYQC TVKLRAWSTN EKDVKDACMS RIPYYITHAK 120
  121 PENAETSCTF QMNLH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.522879
Match: 1tozA
Description: NMR structure of the human NOTCH-1 ligand binding region
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [136-333]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CDDNYWQIHG RCYRVFDGKY TFEEAQQIKL NILLNDMEGI YDAWVTVPNI KDYFTNGQGE  60
   61 AEVYVQDSAY KYDVRPGSIM MDRLEGRHQV LCEYKPAMTM AEMFYMAKLY SEIYPIHVYT 120
  121 HGAIFTSASY LTVTQRSLIK NTGGPTQYGD EIEKFDTSEL NEKCKLLGNI LNVDSIPMVP 180
  181 TENEQNYVKH LLTDHQFY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.221849
Match: 1bj3A
Description: Snake coagglutinin alpha chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.13629480035749 bayes_pls_golite062009
carbohydrate binding 0.44675717945952 bayes_pls_golite062009
protein binding 0.059857076934361 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [334-405]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSGFKSDGC GRGDYRTQQD GNTSTSFDSI GSNDEYCHAH RNGRYPTMAA MRAPAICAMH  60
   61 EFSWSHGDCD PK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [406-556]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEWAEEMLVY NRTSESVFCH YVDETEKITY YEAKARCNSF GAELTGFDSR DEWVAVSKTL  60
   61 KTCHHWTGGI TKYKSYNVPE IIWDAGVATN TDYFTDVYFQ TTLPDEHLSL LWSEAHVHPT 120
  121 YRNYMYMCTI CGKAAKLVRS EGKVYGLKTT G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.69897
Match: 2h2rA
Description: No description for 2h2rA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle