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View Structure Prediction Details

Protein: CE37992
Organism: Caenorhabditis elegans
Length: 653 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE37992.

Description E-value Query
Range
Subject
Range
gi|157762944 - gi|157762944|ref|XP_001673814.1| Hypothetical protein CBG23139 [Caenorhabditis briggsae AF16]
gi|187021258, gi... - gi|39591973|emb|CAE75193.1| Hypothetical protein CBG23139 [Caenorhabditis briggsae], gi|187021258|em...
471.0 [0..1] [652..1]

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Predicted Domain #1
Region A:
Residues: [1-512]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELWKSCIFL FLNFCIQSEG IVRTSYGNWN IPKIGDRNIP SFLIDESKNQ FLLDGLPFRY  60
   61 ISGSIHYFRI PRDRWDERLG KVRALGFNAI QYYIPWNMHE LEEGNHDFSG LLDFAEFSMM 120
  121 AFHKYGLWTI LRVGPYICGE LENGGLPWWL LNKNVTKQRS SDRVFTREVE NWFEILLPRV 180
  181 KPLLRKNGGP VLMLQIENEY GSYDACDQQY LRFLRDLTRS LVGDDVLLFT TDGSAESLLK 240
  241 CGTVEGVFPT VDFGPTDDAK EIENNFKLQR KFAPNGPLVN SEYYPGWLVL WGQKKQNLPS 300
  301 PQTIINGSQT MYSLGASFNY YMIHGGTNFG FWNGAETEAP CITSYDYDAP ISESGDVTTK 360
  361 YLEIRKWIKG LTDWPTPPLD VPGNSPKGRF GKIKMRLVHS VEKLKTLTSL GDPGDCVETD 420
  421 KPISFETLKH PLGLVAYQAK INSCGNLTIP SFGDFVHVYL NGKYIDTLTR RYYNLTRNSV 480
  481 IIEGCLENEE NRLFMLVENQ GRKTFETIND RK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.0
Match: 1tg7A
Description: Native structure of beta-galactosidase from Penicillium sp.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity, hydrolyzing O-glycosyl compounds 6.26329339735894 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 5.92180849080637 bayes_pls_golite062009
hydrolase activity 3.98075336331567 bayes_pls_golite062009
hexosaminidase activity 3.21852337137039 bayes_pls_golite062009
beta-N-acetylhexosaminidase activity 2.69072465526737 bayes_pls_golite062009
catalytic activity 1.85569074294201 bayes_pls_golite062009
glucosidase activity 1.85545420386612 bayes_pls_golite062009
galactosidase activity 1.26155841119987 bayes_pls_golite062009
sugar binding 1.05517664149942 bayes_pls_golite062009
alpha-glucosidase activity 1.00973231642658 bayes_pls_golite062009
beta-glucuronidase activity 0.55376725638834 bayes_pls_golite062009
mannosidase activity 0.48536369022293 bayes_pls_golite062009
carbohydrate binding 0.36193860645628 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 0.266938437560648 bayes_pls_golite062009
binding 0.129334455670168 bayes_pls_golite062009
beta-galactosidase activity 0.0137149865738109 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [513-653]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GILSDVFMNG QAIQFWTQCG IKLPLQEDFY FRKAMRNNYR KNVKSNQKQG VFIGILSVDA  60
   61 PTDTWLDTTG WGKGIAIVNG RNFGRYWPTK GPQMTLYIPA EFLKIGENSV MMVELEGAEE 120
  121 ACTSTSSCIA DFIDHPVFDF Q

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.08
Match: 1bhgA
Description: beta-Glucuronidase; beta-Glucuronidase, domain 3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
sugar binding 1.88707446766738 bayes_pls_golite062009
monosaccharide binding 1.5016957206605 bayes_pls_golite062009
hydrolase activity 1.33447645932315 bayes_pls_golite062009
binding 1.18625504714684 bayes_pls_golite062009
carbohydrate binding 1.13274900486168 bayes_pls_golite062009
peptidase activity 0.619147192549203 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.338739134947705 bayes_pls_golite062009
fucose binding 0.25045987594275 bayes_pls_golite062009
protein binding 0.0768945417872265 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle