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View Structure Prediction Details

Protein: gale-1
Organism: Caenorhabditis elegans
Length: 349 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gale-1.

Description E-value Query
Range
Subject
Range
gi|221325375 - gi|221325375|ref|ZP_03606669.1| UDP-glucose 4-epimerase [Bacillus subtilis subsp. subtilis str. SMY]
gi|221321091 - gi|221321091|ref|ZP_03602385.1| UDP-glucose 4-epimerase [Bacillus subtilis subsp. subtilis str. JH64...
gi|221316179 - gi|221316179|ref|ZP_03597984.1| UDP-glucose 4-epimerase [Bacillus subtilis subsp. subtilis str. NCIB...
GALE_BACSU - UDP-glucose 4-epimerase OS=Bacillus subtilis (strain 168) GN=galE PE=3 SV=1
GALE_BACSU - UDP-glucose 4-epimerase OS=Bacillus subtilis GN=galE PE=3 SV=1
362.0 [0..1] [349..1]

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Predicted Domain #1
Region A:
Residues: [1-349]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHILVTGAAG FIGSHTVLEL LNSGYTVLCI DNFANAISVT DEHGNAISLK RVAQLTGKDV  60
   61 PFQNVDVCDE AALEKVFSEN KFDGIIHLAA LKAVGESVAK PLQYYSNNLV ASLNLIQMCL 120
  121 KYNVKNFVFS SSATVYGPPS ELPITEKSQT GQGITNPYGQ TKYMMEQILI DVGKANPEWN 180
  181 VVLLRYFNPV GAHKSGLIGE DPKGVPNNLM PYVSQVAIGK LPVLTIYGDQ FDTVDGTGVR 240
  241 DYIHVVDLAK GHVKAFDRIK TVGNIGTEIY NLGTGVGYSV RQMVDALKKV SGRDIPVKIG 300
  301 VPRPGDVASV YCDPSLAQEK LGWRAETGLE EMCADLWNWQ TKNPQGFSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.0
Match: 1hzjA
Description: Uridine diphosphogalactose-4-epimerase (UDP-galactose 4-epimerase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
UDP-glucose 4-epimerase activity 2.13934644118967 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.03956654822048 bayes_pls_golite062009
nucleic acid binding 0.868888700854563 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.82673050487418 bayes_pls_golite062009
DNA binding 0.790382977752475 bayes_pls_golite062009
binding 0.784517759335365 bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity 0.65743456407889 bayes_pls_golite062009
transcription regulator activity 0.613310508772122 bayes_pls_golite062009
retinol dehydrogenase activity 0.48941662111046 bayes_pls_golite062009
transcription factor activity 0.11102650759187 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle