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View Structure Prediction Details

Protein: nkat-3
Organism: Caenorhabditis elegans
Length: 424 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nkat-3.

Description E-value Query
Range
Subject
Range
gi|18977625, gi|... - gi|18977625|ref|NP_578982.1| aspartate aminotransferase [Pyrococcus furiosus DSM 3638], gi|18893347|...
360.0 [0..8] [424..2]

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Predicted Domain #1
Region A:
Residues: [1-424]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSFAPKPA ERTAQHSASI WVEFTTLAAE TKAVNLGQGF PDSPAPKFVT DLLENLSKHP  60
   61 ELTAAHQYTR GYGHPMLVDI LAKMYSHFYN VQVDPMNEVL VTVGAYLSLY YAFLGWVNKG 120
  121 DEVLIIEPAY DCYYPQVKFA GGVPVPVVMN LAEGATSASQ FTIDFADMES KINEKTKMLV 180
  181 INNPHNPTGK LFSRHELEKL AEIAKKHNLI VIADEVYEFH VWDKNDMVRF ASLPGMYERT 240
  241 ISIGSAGKAF SVTGWKLGWA VGPKQLLEPL KAIHQNCVFT CSTPTQMAIA EAFRLDWPKF 300
  301 LSDPENSYLA TGLSGELRAK RDKLAKMLEE GNFRPIIPDA GYFMLADYVH LKEGINLPTE 360
  361 EDPDDFVFSR WLCREKKLAV IPPSAFYSAR DNKLKNSNMV RLCYFKKDET LDAAEEILKK 420
  421 LGKQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.522879
Match: 1yiyA
Description: Aedes aegypti kynurenine aminotransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
L-aspartate:2-oxoglutarate aminotransferase activity 5.51961002550688 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity 1.63055151623667 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 1.63055151623667 bayes_pls_golite062009
transferase activity 1.44093490824786 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.28316822767388 bayes_pls_golite062009
transaminase activity 1.24990480711889 bayes_pls_golite062009
4-aminobutyrate transaminase activity 0.99097016439114 bayes_pls_golite062009
5-aminolevulinate synthase activity 0.54326874956263 bayes_pls_golite062009
transferase activity, transferring acyl groups 0.319452731970428 bayes_pls_golite062009
pyridoxal phosphate binding 0.16957228630576 bayes_pls_golite062009
vitamin B6 binding 0.16957228630576 bayes_pls_golite062009
aromatic-amino-acid:2-oxoglutarate aminotransferase activity 0.0916183433120769 bayes_pls_golite062009
cystathionine beta-lyase activity 0.0833010353195099 bayes_pls_golite062009
nucleic acid binding 0.013097682076602 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle