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View Structure Prediction Details

Protein: tag-19
Organism: Caenorhabditis elegans
Length: 611 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tag-19.

Description E-value Query
Range
Subject
Range
gi|108869263, gi... - gi|157104119|ref|XP_001648263.1| aromatic amino acid decarboxylase [Aedes aegypti], gi|108869263|gb|...
372.0 [0..107] [569..4]

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Predicted Domain #1
Region A:
Residues: [1-113]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGAEVPALIV CLVVSLCFNA GFIVYFVLKR KSEKVSEYKK VENPDVENFS KSSVRPPPPE  60
   61 PKPQRSPPDR EKESKDPQPM NNNRSKEHVL RSENQAPTNE IQQRSDRQKL QEP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [114-611]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGKNEFIKCM SLVVQFINDY FDESHKQPVI PENDVNSSRI HVKVPEKAEE LTEILKDLKE  60
   61 IVIPNICHTH HPRYHAKFAG KSLADLVAST ISAALGHDVN SSPIIESIER IICKWLSTSM 120
  121 AIPQIKSSLG ELRDPIGTVF YTPCDVFISV IRHAIEKFEK TDSGKERSKN ADYIVYCSDD 180
  181 SQVPLKEPCI SCRVKLRKVI TDEKNGSGMT SANLLKQMEK DIARGFTPLV IIANYGSANI 240
  241 AANDEIWDLV TVSRSKKIWL HLDASYAGCE WLDSNSRNNV HALISEVHSV HITCSSLFPY 300
  301 SGRISVVWSC EKLELDGAKI LYGEHPIRLW ILIRLHGIRS IREAVKRKII LGNAFSERMS 360
  361 HHSQLFEMHH TNEHGVTVFQ YKNKKIKDRT EDTNKITSMF HNYLVLSSTL KFSIVSFHGK 420
  421 VLIKSVVNYG RCNLSIMDES VSTLVNSVDE FEEALKKKKK IVCETPKNEF CEMIGGSPNE 480
  481 TTDTTQSDDG IDKKKKKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.0
Match: 1js3A
Description: DOPA decarboxylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 2.29878871754893 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.28316822767388 bayes_pls_golite062009
transaminase activity 1.24990480711889 bayes_pls_golite062009
transferase activity 0.737426388870721 bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity 0.130698724135981 bayes_pls_golite062009
carbon-carbon lyase activity 0.11598778799668 bayes_pls_golite062009
aromatic-L-amino-acid decarboxylase activity 0.10589462882093 bayes_pls_golite062009
binding 0.0138724523355769 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle