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View Structure Prediction Details

Protein: taf-4
Organism: Caenorhabditis elegans
Length: 523 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for taf-4.

Description E-value Query
Range
Subject
Range
gi|76633512 - gi|76633512|ref|XP_606138.2| PREDICTED: similar to Protein CBFA2T2 (MTG8-like protein) (MTG8-related...
253.0 [0..20] [517..50]

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Predicted Domain #1
Region A:
Residues: [1-97]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLPRFRLVQ GKAIGERSTP GVSTPEPAPP QIKQEVDYQD AHQMAPEPVE APQAQNHQMQ  60
   61 PPRQPIQQQM QHFQSPSPMA PQGPPGTPQN SAAAAAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [98-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASDDKNVTKC VRFLKTLINL SNNDDPEMPD KAARVKELIR GVIYLETTAE EFTRNLQQVL  60
   61 KSQAQPHLLP FLQNTLPALR NAVRNGTASV EGVNPPPGYV FNNGRTPGPP QPPPPQQQSQ 120
  121 QQPPLEMRQI P

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.28
Match: 2p6vA
Description: No description for 2p6vA was found.

Predicted Domain #3
Region A:
Residues: [229-338]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPNQIPPQMV QGGPHMVSVG ARPMIRPMGP GGPSPMGLQG PVRGPMGHQM VQMHPPPPPQ  60
   61 QIQQQHPAPP VEMEVEENLQ PTAAATATRQ YPEGSLKSSI LKPDEVLNRI 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [339-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKRMMSSCSV EEEALVAISD AVESHLRELI TLMAGVAEHR VESLRIPE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.25
Match: 1h3oA
Description: TAF(II)-135, (TAF(II)-130, hTAF4), histone fold domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.61022191882652 bayes_pls_golite062009
DNA binding 0.796700929077419 bayes_pls_golite062009
nucleic acid binding 0.653799394985054 bayes_pls_golite062009
transcription regulator activity 0.409034934848948 bayes_pls_golite062009
protein binding 0.20067182931644 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [387-523]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYVAIDDVKR QLRFLEDLDR QEEELRESRE KESLIRMSKN KNSGKETIEK AKEMQRQDAE  60
   61 AKRNRDANAA AIAALSSNKT VKNKWENTGA ATTAPRPRTV RVTTRDLHLL VNQDSRFTGT 120
  121 FIREKMSYGG PAVDTTI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 2i1jA
Description: No description for 2i1jA was found.

YRC Informatics Platform - Version 3.0
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