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View Structure Prediction Details

Protein: taf-4
Organism: Caenorhabditis elegans
Length: 523 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for taf-4.

Description E-value Query
Range
Subject
Range
gi|76633512 - gi|76633512|ref|XP_606138.2| PREDICTED: similar to Protein CBFA2T2 (MTG8-like protein) (MTG8-related...
253.0 [0..20] [517..50]

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Predicted Domain #1
Region A:
Residues: [1-97]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLPRFRLVQ GKAIGERSTP GVSTPEPAPP QIKQEVDYQD AHQMAPEPVE APQAQNHQMQ  60
   61 PPRQPIQQQM QHFQSPSPMA PQGPPGTPQN SAAAAAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [98-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASDDKNVTKC VRFLKTLINL SNNDDPEMPD KAARVKELIR GVIYLETTAE EFTRNLQQVL  60
   61 KSQAQPHLLP FLQNTLPALR NAVRNGTASV EGVNPPPGYV FNNGRTPGPP QPPPPQQQSQ 120
  121 QQPPLEMRQI P

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.28
Match: 2p6vA
Description: No description for 2p6vA was found.

Predicted Domain #3
Region A:
Residues: [229-338]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPNQIPPQMV QGGPHMVSVG ARPMIRPMGP GGPSPMGLQG PVRGPMGHQM VQMHPPPPPQ  60
   61 QIQQQHPAPP VEMEVEENLQ PTAAATATRQ YPEGSLKSSI LKPDEVLNRI 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [339-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKRMMSSCSV EEEALVAISD AVESHLRELI TLMAGVAEHR VESLRIPE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.25
Match: 1h3oA
Description: TAF(II)-135, (TAF(II)-130, hTAF4), histone fold domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.61022191882652 bayes_pls_golite062009
DNA binding 0.796700929077419 bayes_pls_golite062009
nucleic acid binding 0.653799394985054 bayes_pls_golite062009
transcription regulator activity 0.409034934848948 bayes_pls_golite062009
protein binding 0.20067182931644 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [387-523]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYVAIDDVKR QLRFLEDLDR QEEELRESRE KESLIRMSKN KNSGKETIEK AKEMQRQDAE  60
   61 AKRNRDANAA AIAALSSNKT VKNKWENTGA ATTAPRPRTV RVTTRDLHLL VNQDSRFTGT 120
  121 FIREKMSYGG PAVDTTI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 2i1jA
Description: No description for 2i1jA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle