YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|1184684, gi\|1...
Organism:	Pseudomonas aeruginosa
Length:	474 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1184684, gi|1....

Description	E-value	Query Range	Subject Range
gi\|12963467 - gi\|12963467\|gb\|AAK11276.1\|AF343973_1 MucD [Pseudomonas aeruginosa] gi\|115583903, gi... - gi\|116048682\|ref\|YP_792518.1\| serine protease MucD precursor [Pseudomonas aeruginosa UCBPP-PA14], gi...	0.0	[1..474]	[1..474]
gi\|94418130 - gi\|94418130\|ref\|ZP_01297946.1\| hypothetical protein PaerP_01000281 [Pseudomonas aeruginosa PA7]	0.0	[11..474]	[1..464]
gi\|84322784 - gi\|84322784\|ref\|ZP_00970866.1\| COG0265: Trypsin-like serine proteases, typically periplasmic, contai...	0.0	[11..474]	[1..464]
gi\|84316733 - gi\|84316733\|ref\|ZP_00965199.1\| COG0265: Trypsin-like serine proteases, typically periplasmic, contai... gi\|107100227 - gi\|107100227\|ref\|ZP_01364145.1\| hypothetical protein PaerPA_01001250 [Pseudomonas aeruginosa PACS2]	0.0	[11..474]	[1..464]
DEGPL_PSEF5 - Probable periplasmic serine endoprotease DegP-like OS=Pseudomonas fluorescens (strain Pf-5 / ATCC BA...	0.0	[1..474]	[3..476]
DEGPL_PSEP1 - Probable periplasmic serine endoprotease DegP-like OS=Pseudomonas putida (strain F1 / ATCC 700007) G...	0.0	[1..474]	[3..477]
gi\|95112253, gi\|... - gi\|95112253\|emb\|CAK16980.1\| serine protease MucD [Pseudomonas entomophila L48], gi\|104783266\|ref\|YP_... gi\|95112253 - gi\|95112253\|emb\|CAK16980.1\| serine protease MucD [Pseudomonas entomophila L48]	0.0	[1..474]	[3..479]
gi\|26988163, gi\|... - gi\|26988163\|ref\|NP_743588.1\| protease Do [Pseudomonas putida KT2440], gi\|24982897\|gb\|AAN67052.1\|AE01...	0.0	[1..474]	[18..492]
gi\|77457592, gi\|... - gi\|77457592\|ref\|YP_347097.1\| peptidase S1C, Do [Pseudomonas fluorescens Pf0-1], gi\|77381595\|gb\|ABA73...	8.0E-99	[1..474]	[3..482]
DEGPL_PSE14 - Probable periplasmic serine endoprotease DegP-like OS=Pseudomonas savastanoi pv. phaseolicola (strai...	1.0E-98	[1..474]	[3..479]

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Predicted Domain #1

Region A:
Residues: [1-474]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHTLKRCMAA MVALLALSLA MTARAELPDF TPLVEQASPA VVNISTRQKL PDRAMARGQL  60
   61 SIPDLEGLPP MFRDFLERSI PQVPRNPRGQ QREAQSLGSG FIISNDGYIL TNNHVVADAD 120
  121 EILVRLSDRS EHKAKLIGAD PRSDVAVLKI EAKNLPTLKL GDSNKLKVGE WVLAIGSPFG 180
  181 FDHSVTAGIV SAKGRSLPNE SYVPFIQTDV AINPGNSGGP LLNLQGEVVG INSQIFTRSG 240
  241 GFMGLSFAIP IDVALNVADQ LKKAGKVSRG WLGVVIQEVN KDLAESFGLD KPSGALVAQL 300
  301 VEDGPAAKGG LQVGDVILSL NGQSINESAD LPHLVGNMKP GDKINLDVIR NGQRKSLSMA 360
  361 VGSLPDDDEE IASMGAPGAE RSSNRLGVTV ADLTAEQRKS LDIQGGVVIK EVQDGPAAVI 420
  421 GLRPGDVITH LDNKAVTSTK VFADVAKALP KNRSVSMRVL RQGRASFITF KLAE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	82.0
Match:	1ky9A
Description:	Protease Do (DegP, HtrA), C-terminal domains; Protease Do (DegP, HtrA), catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein binding	2.10639523340529	bayes_pls_golite062009
hydrolase activity	1.95262287761731	bayes_pls_golite062009
binding	1.92577219161709	bayes_pls_golite062009
peptidase activity	0.892956033345508	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.644798716305534	bayes_pls_golite062009
endopeptidase activity	0.323781287331288	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: