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View Structure Prediction Details

Protein: NAT12_ARATH
Organism: Arabidopsis thaliana
Length: 709 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NAT12_ARATH.

Description E-value Query
Range
Subject
Range
gi|25407923, gi|... - gi|3860251|gb|AAC73019.1| putative membrane transporter [Arabidopsis thaliana], pir||C84677 probable...
302.0 [0..20] [709..20]

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Predicted Domain #1
Region A:
Residues: [1-172]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSDPKPGP KPGPWPPTPE SAAMPPSSWA KKTGFRPKFS GETTATDSSS GQLSLPVRAK  60
   61 QQETQPDLEA GQTRLRPPPP VSAAVTNGET DKDKKEKPPP PPPGSVAVPV KDQPVKRRRD 120
  121 SDGVVGRSNG PDGANGSGDP VRRPGRIEET VEVLPQSMDD DLVARNLHMK YG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [173-240]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRDTPGLVPI GFYGLQHYLS MLGSLILVPL VIVPAMGGSH EEVANVVSTV LFVSGITTLL  60
   61 HTSFGSRL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [241-709]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLIQGPSFVF LAPALAIINS PEFQGLNGNN NFKHIMRELQ GAIIIGSAFQ AVLGYSGLMS  60
   61 LILRLVNPVV VAPTVAAVGL SFYSYGFPLV GKCLEIGVVQ ILLVIIFALY LRKISVLSHR 120
  121 IFLIYAVPLS LAITWAAAFL LTETGAYTYK GCDPNVPVSN VVSTHCRKYM TRMKYCRVDT 180
  181 SHALSSAPWF RFPYPLQWGV PLFNWKMAFV MCVVSVIASV DSVGSYHASS LLVASRPPTR 240
  241 GVVSRAIGLE GFTSVLAGLW GTGTGSTTLT ENVHTIAVTK MGSRRVVELG ACVLVIFSLV 300
  301 GKVGGFLASI PQVMVASLLC FMWAMFTALG LSNLRYSEAG SSRNIIIVGL SLFFSLSVPA 360
  361 YFQQYGISPN SNLSVPSYYQ PYIVSSHGPF KSQYKGMNYV MNTLLSMSMV IAFIMAVILD 420
  421 NTVPGSKQER GVYVWSDSET ATREPALAKD YELPFRVGRF FRWVKWVGI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.69897
Match: 1fftA
Description: Cytochrome O ubiquinol oxidase, subunit I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrogen ion transmembrane transporter activity 8.24398014668904 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 8.08849452849835 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 7.42160577074767 bayes_pls_golite062009
transporter activity 4.2806100513341 bayes_pls_golite062009
transmembrane transporter activity 4.19885907933483 bayes_pls_golite062009
substrate-specific transporter activity 4.09889747645813 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 4.04906705514063 bayes_pls_golite062009
ion transmembrane transporter activity 4.02368756819781 bayes_pls_golite062009
cation transmembrane transporter activity 3.98341278118156 bayes_pls_golite062009
catalytic activity 1.95966890211023 bayes_pls_golite062009
heme-copper terminal oxidase activity 1.27735515053931 bayes_pls_golite062009
oxidoreductase activity 1.2337539211606 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 0.803860393147327 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 0.803860393147327 bayes_pls_golite062009
cytochrome-c oxidase activity 0.803860393147327 bayes_pls_golite062009
binding 0.666039242029224 bayes_pls_golite062009
active transmembrane transporter activity 0.349031670056176 bayes_pls_golite062009
primary active transmembrane transporter activity 0.336122020727214 bayes_pls_golite062009
protein binding 0.0827883348198969 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle