YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|11268131
Organism:	Neisseria meningitidis
Length:	212 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|11268131.

Description	E-value	Query Range	Subject Range
gi\|113461739, gi... - gi\|23467619\|ref\|ZP_00123199.1\| COG0800: 2-keto-3-deoxy-6-phosphogluconate aldolase [Haemophilus somn...	180.0	[0..5]	[210..7]
gi\|170718550, gi... - gi\|53728725\|ref\|ZP_00131830.2\| COG0800: 2-keto-3-deoxy-6-phosphogluconate aldolase [Haemophilus somn...	178.0	[0..5]	[210..7]
gi\|32033966 - gi\|32033966\|ref\|ZP_00134222.1\| COG0800: 2-keto-3-deoxy-6-phosphogluconate aldolase [Actinobacillus p...	174.0	[0..1]	[211..1]
gi\|108563462, gi... - gi\|108563462\|ref\|YP_627778.1\| 2-keto-3-deoxy-6-phosphogluconate aldolase [Helicobacter pylori HPAG1]...	173.0	[0..2]	[208..1]
gi\|59714170, gi\|... - gi\|59714170\|ref\|YP_206945.1\| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Vi...	172.0	[0..1]	[209..1]
gi\|54308469, gi\|... - gi\|54308469\|ref\|YP_129489.1\| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Ph...	171.0	[0..2]	[210..1]
gi\|7436631 - pir\|\|C64657 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) - Helicobacter pylori (strain ... gi\|2314248, gi\|1... - gi\|2314248\|gb\|AAD08142.1\| 2-keto-3-deoxy-6-phosphogluconate aldolase (eda) [Helicobacter pylori 2669...	171.0	[0..2]	[208..1]
gi\|53802784, gi\|... - gi\|53802784\|ref\|YP_112578.1\| 4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldo...	171.0	[0..2]	[208..13]
gi\|56380333, gi\|... - gi\|56420491\|ref\|YP_147809.1\| 2-dehydro-3-deoxyphosphogluconate aldolase [Geobacillus kaustophilus HT...	171.0	[0..1]	[212..1]
gi\|240118073 - gi\|240118073\|ref\|ZP_04732135.1\| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase ... gi\|59801133, gi\|... - gi\|59801133\|ref\|YP_207845.1\| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Ne... gi\|240115778 - gi\|240115778\|ref\|ZP_04729840.1\| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase ... gi\|240113021 - gi\|240113021\|ref\|ZP_04727511.1\| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase ...	170.0	[0..1]	[212..1]

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Predicted Domain #1

Region A:
Residues: [1-212]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKLTPREIL TAGAVVPVMA IDDLSTAIDL SHALVEGGIP TLEITLRTPV GLDAIRLIAK  60
   61 EVPNAIVGAG TVTNPEQLKA VEDAGAVFAI SPGLHESLAK AGHNSGIPLI PGVATPGEIQ 120
  121 LALEHGIDTL KLFPAEVVGG KAMLKALYGP YADVRFCPTG GISLATAPEY LALPNVLCVG 180
  181 GSWLTPKEAV KNKDWDTITR LAKEAAALKP KA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.09691
Match:	1vhcA
Description:	Crystal structure of a putative KHG/KDPG aldolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
2-dehydro-3-deoxy-phosphogluconate aldolase activity	3.5031381823147	bayes_pls_golite062009
catalytic activity	2.67031204377352	bayes_pls_golite062009
fructose-bisphosphate aldolase activity	0.840107349031025	bayes_pls_golite062009
lyase activity	0.740424046054758	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	0.643395146148785	bayes_pls_golite062009
transferase activity	0.464721888799972	bayes_pls_golite062009
aldehyde-lyase activity	0.351872954170322	bayes_pls_golite062009
transaldolase activity	0.337067552042715	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: