YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|15804636, gi\|...
Organism:	Escherichia coli O157:H7 str. EDL933
Length:	202 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|15804636, gi|....

Description	E-value	Query Range	Subject Range
gi\|2293118 - gi\|2293118\|gb\|AAB68649.1\| LexA [unidentified cloning vector]	209.0	[0..1]	[202..1]
LEXA_AERHY - (Q44069) LexA repressor (EC 3.4.21.88)	207.0	[0..1]	[202..1]
gi\|200388085, gi... - gi\|200388085\|ref\|ZP_03214697.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Virchow ... LEXA_SALDC - LexA repressor OS=Salmonella dublin (strain CT_02021853) GN=lexA PE=3 SV=1 LEXA_SALPK - LexA repressor OS=Salmonella paratyphi A (strain AKU_12601) GN=lexA PE=3 SV=1 gi\|197241491, gi... - gi\|197263236\|ref\|ZP_03163310.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Saintpau... gi\|213052230 - gi\|213052230\|ref\|ZP_03345108.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi st... LEXA_SALEP - LexA repressor OS=Salmonella enteritidis PT4 (strain P125109) GN=lexA PE=3 SV=1 LEXA_SALG2 - LexA repressor OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=lexA PE=3 SV=1 gi\|204927146, gi... - gi\|204927146\|ref\|ZP_03218348.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Javiana ... LEXA_SALNS - LexA repressor OS=Salmonella newport (strain SL254) GN=lexA PE=3 SV=1 gi\|195630596, gi... - gi\|195630596\|gb\|EDX49208.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Newport str.... gi\|205347902, gi... - gi\|205347902\|gb\|EDZ34533.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Hadar str. R... gi\|205337302, gi... - gi\|205337302\|gb\|EDZ24066.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Heidelberg s... LEXA_SALA4 - LexA repressor OS=Salmonella agona (strain SL483) GN=lexA PE=3 SV=1 LEXA_SALSV - LexA repressor OS=Salmonella schwarzengrund (strain CVM19633) GN=lexA PE=3 SV=1 gi\|194472176, gi... - gi\|194472176\|ref\|ZP_03078160.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Kentucky... LEXA_SALHS - LexA repressor OS=Salmonella heidelberg (strain SL476) GN=lexA PE=3 SV=1 LEXA_SALPB - LexA repressor OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=lexA PE=3 SV=1 LEXA_SALAR - LexA repressor OS=Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) GN=lexA PE=3 SV=1 LEXA_SALCH - LexA repressor OS=Salmonella choleraesuis (strain SC-B67) GN=lexA PE=3 SV=1 LEXA_SALPA - LexA repressor OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=lexA PE=3 SV=1 gi\|213647510 - gi\|213647510\|ref\|ZP_03377563.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi st... gi\|213619392 - gi\|213619392\|ref\|ZP_03373218.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi st... LEXA_SALTI - LexA repressor OS=Salmonella typhi GN=lexA PE=3 SV=1 gi\|213424504 - gi\|213424504\|ref\|ZP_03357301.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi st... LEXA_SALTI - LexA repressor OS=Salmonella typhi GN=lexA PE=3 SV=1 gi\|213423564 - gi\|213423564\|ref\|ZP_03356544.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi st... LEXA_SALTY - LexA repressor OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=lexA PE=3 SV=1 gi\|29144405, gi\|... - gi\|29144405\|ref\|NP_807747.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi str. ... LEXA_SALPC - LexA repressor OS=Salmonella paratyphi C (strain RKS4594) GN=lexA PE=3 SV=1 gi\|16762918 - gi\|16762918\|ref\|NP_458535.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi str. ... gi\|214000133 - gi\|214000133\|ref\|ZP_03410868.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi st... gi\|213859894 - gi\|213859894\|ref\|ZP_03385598.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi st... gi\|238913014 - gi\|238913014\|ref\|ZP_04656851.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Tennesse... LEXA_SALCH - LexA repressor OS=Salmonella choleraesuis GN=lexA PE=3 SV=1 LEXA_SALTY - LexA repressor OS=Salmonella typhimurium GN=lexA PE=3 SV=1 gi\|168239348, gi... - gi\|197287939\|gb\|EDY27327.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Schwarzengru... LEXA_SALPB - LexA repressor OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=lexA PE=3 SV=1 gi\|205334379, gi... - gi\|205334379\|gb\|EDZ21143.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Kentucky str... gi\|205330205, gi... - gi\|205330205\|gb\|EDZ16969.1\| LexA repressor [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-... gi\|205322831, gi... - gi\|205322831\|gb\|EDZ10670.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Saintpaul st... LEXA_SALCH - LexA repressor OS=Salmonella choleraesuis GN=lexA PE=3 SV=1 lcl\|NC_016856.1_... - [gene=lexA] [protein=LexA repressor] [protein_id=YP_005240529.1] [location=4472790..4473398] LEXA_SALPA - LexA repressor OS=Salmonella paratyphi A GN=lexA PE=3 SV=1 LEXA_SALTY - LexA repressor OS=Salmonella typhimurium GN=lexA PE=3 SV=1	207.0	[0..1]	[202..1]
gi\|47768, gi\|552... - pir\|\|ILEBT lexA protein - Salmonella typhimurium, gi\|552020\|gb\|AAA27157.1\| lexA [Salmonella enteric... gi\|47768\|emb\|CAA... - lexA, LexA protein [Salmonella typhimurium]	206.0	[0..1]	[202..1]
gi\|15988320, gi\|... - gi\|15988321\|pdb\|1JHH\|B Chain B, Lexa S119a Mutant, gi\|15988320\|pdb\|1JHH\|A Chain A, Lexa S119a Mutant	206.0	[0..1]	[202..1]
gi\|90406768, gi\|... - gi\|90406768\|ref\|ZP_01214961.1\| LexA repressor [Psychromonas sp. CNPT3], gi\|90312221\|gb\|EAS40313.1\| L...	204.0	[0..1]	[202..1]
gi\|229706255, gi... - gi\|229836571\|ref\|ZP_04456737.1\| DNA-binding transcriptional repressor of SOS regulon [Yersinia pesti... gi\|229696545, gi... - gi\|229840179\|ref\|ZP_04460338.1\| DNA-binding transcriptional repressor of SOS regulon [Yersinia pesti... LEXA_YERPE - LexA repressor OS=Yersinia pestis GN=lexA PE=3 SV=1 gi\|229690571, gi... - gi\|229842261\|ref\|ZP_04462416.1\| DNA-binding transcriptional repressor of SOS regulon [Yersinia pesti... gi\|149290047, gi... - gi\|150260639\|ref\|ZP_01917367.1\| LexA repressor [Yersinia pestis CA88-4125], gi\|149290047\|gb\|EDM40124... LEXA_YERPP - LexA repressor OS=Yersinia pestis (strain Pestoides F) GN=lexA PE=3 SV=1 LEXA_YERPS - LexA repressor OS=Yersinia pseudotuberculosis GN=lexA PE=3 SV=1 LEXA_YERPG - LexA repressor OS=Yersinia pestis bv. Antiqua (strain Angola) GN=lexA PE=3 SV=1 gi\|165926677, gi... - gi\|165926677\|ref\|ZP_02222509.1\| LexA repressor [Yersinia pestis biovar Orientalis str. F1991016], gi... LEXA_YERP3 - LexA repressor OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=lexA PE=3 SV=1 gi\|165936375, gi... - gi\|89104133\|ref\|ZP_01176685.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... LEXA_YERPA - LexA repressor OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=lexA PE=3 SV=1 LEXA_YERPN - LexA repressor OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=lexA PE=3 SV=1 gi\|22124486, gi\|... - gi\|22124486\|ref\|NP_667909.1\| LexA repressor [Yersinia pestis KIM], gi\|21957278\|gb\|AAM84160.1\|AE01365... LEXA_YERPS - LexA repressor OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=lexA PE=3 SV=1 gi\|45435180, gi\|... - gi\|45440324\|ref\|NP_991863.1\| LexA repressor [Yersinia pestis biovar Microtus str. 91001], gi\|4543518... gi\|166204939, gi... - gi\|166213964\|ref\|ZP_02239999.1\| LexA repressor [Yersinia pestis biovar Antiqua str. B42003004], gi\|1... gi\|16120652, gi\|... - gi\|218927520\|ref\|YP_002345395.1\| LexA repressor [Yersinia pestis CO92], gi\|16120652\|ref\|NP_403965.1\|... gi\|165990491, gi... - gi\|166010401\|ref\|ZP_02231299.1\| LexA repressor [Yersinia pestis biovar Antiqua str. E1979001], gi\|16... gi\|167418922, gi... - gi\|167418922\|ref\|ZP_02310675.1\| LexA repressor [Yersinia pestis biovar Orientalis str. MG05-1020], g... gi\|167402457, gi... - gi\|167402457\|ref\|ZP_02307914.1\| LexA repressor [Yersinia pestis biovar Antiqua str. UG05-0454], gi\|1... gi\|167467145 - gi\|167467145\|ref\|ZP_02331849.1\| LexA repressor [Yersinia pestis FV-1] gi\|167426198, gi... - gi\|167426198\|ref\|ZP_02317951.1\| LexA repressor [Yersinia pestis biovar Mediaevalis str. K1973002], g... LEXA_YERPB - LexA repressor OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=lexA PE=3 SV=1 LEXA_YERPY - LexA repressor OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=lexA PE=3 SV=1	203.0	[0..1]	[202..1]
gi\|71735052, gi\|... - gi\|71735052\|ref\|YP_275363.1\| LexA repressor [Pseudomonas syringae pv. phaseolicola 1448A], gi\|715556... gi\|213926330, gi... - gi\|213969031\|ref\|ZP_03397171.1\| LexA repressor [Pseudomonas syringae pv. tomato T1], gi\|213926330\|gb... LXA1_PSESM, LEXA... - (Q87ZB9) LexA repressor 1 (EC 3.4.21.88), LexA repressor 1 OS=Pseudomonas syringae pv. tomato GN=lex... LEXA1_PSESM - LexA repressor 1 OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=lexA1 PE=3 SV=1	203.0	[0..1]	[198..1]
LEXA_ERWCA - (Q04596) LexA repressor (EC 3.4.21.88) gi\|227327408 - gi\|227327408\|ref\|ZP_03831432.1\| LexA repressor [Pectobacterium carotovorum subsp. carotovorum WPP14] gi\|255053827, gi... - gi\|255053827\|ref\|ZP_05306077.1\| SOS-response transcriptional repressor, LexA [Pectobacterium wasabia... LEXA_PECCC - LexA repressor OS=Pectobacterium carotovorum subsp. carotovorum GN=lexA PE=3 SV=1	202.0	[0..1]	[201..1]

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Predicted Domain #1

Region A:
Residues: [1-202]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKALTARQQE VFDLIRDHIS QTGMPPTRAE IAQRLGFRSP NAAEEHLKAL ARKGVIEIVS  60
   61 GASRGIRLLQ EEEEGLPLVG RVAAGEPLLA QQHIEGHYQV DPSLFKPNAD FLLRVSGMSM 120
  121 KDIGIMDGDL LAVHKTQDVR NGQVVVARID DEVTVKRLKK QGNKVELLPE NSEFKPIVVD 180
  181 LRQQSFTIEG LAVGVIRNGD WL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.30103
Match:	1jhhA
Description:	LexA repressor, N-terminal DNA-binding domain; LexA C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	1.30784351115827	bayes_pls_golite062009
nucleic acid binding	0.603302373860066	bayes_pls_golite062009
transcription activator activity	0.53294679084865	bayes_pls_golite062009
DNA binding	0.452668330421957	bayes_pls_golite062009
sequence-specific DNA binding	0.44420590157367	bayes_pls_golite062009
catalytic activity	0.415601732277814	bayes_pls_golite062009
binding	0.355412070907203	bayes_pls_golite062009
transcription factor activity	0.0554645717043947	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: