YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|33149273, gi\|...
Organism:	Plasmodium falciparum
Length:	356 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|33149273, gi|....

Description	E-value	Query Range	Subject Range
gi\|67527845, gi\|... - gi\|67527845\|ref\|XP_661778.1\| hypothetical protein AN4174.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	236.0	[0..8]	[350..2]
gi\|159124248 - gi\|159124248\|gb\|EDP49366.1\| lactoylglutathione lyase [Aspergillus fumigatus A1163] gi\|70991673, gi\|... - gi\|70991673\|ref\|XP_750685.1\| lactoylglutathione lyase [Aspergillus fumigatus Af293], gi\|66848318\|gb\|...	231.0	[0..8]	[350..2]
gi\|83767226 - gi\|83767226\|dbj\|BAE57365.1\| unnamed protein product [Aspergillus oryzae] gi\|169769795 - gi\|169769795\|ref\|XP_001819367.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|238487876, gi... - gi\|238487876\|ref\|XP_002375176.1\| lactoylglutathione lyase [Aspergillus flavus NRRL3357], gi\|22070005...	231.0	[0..8]	[349..2]
gi\|90306260, gi\|... - gi\|90306260\|gb\|EAS35891.1\| lactoylglutathione lyase [Coccidioides immitis RS], gi\|119193739\|ref\|XP_0...	228.0	[0..8]	[350..2]
gi\|56495052 - gi\|56495052\|emb\|CAH99110.1\| glyoxalase I, putative [Plasmodium berghei] gi\|68067501 - gi\|68067501\|ref\|XP_675710.1\| glyoxalase [Plasmodium berghei strain ANKA]	225.0	[0..18]	[356..19]
gi\|23481927 - gi\|23481927\|gb\|EAA18062.1\| lactoylglutathione lyase, putative [Plasmodium yoelii yoelii] gi\|82597002 - gi\|82597002\|ref\|XP_726497.1\| lactoylglutathione lyase [Plasmodium yoelii yoelii str. 17XNL]	225.0	[0..18]	[356..19]
gi\|85097393 - gi\|85097393\|ref\|XP_960441.1\| lactoylglutathione lyase [Neurospora crassa OR74A] gi\|28921932, gi\|... - gi\|32407160\|ref\|XP_324172.1\| hypothetical protein [Neurospora crassa], gi\|28921932\|gb\|EAA31205.1\| la...	222.0	[0..6]	[350..2]
gi\|42553364, gi\|... - gi\|46135933\|ref\|XP_389658.1\| hypothetical protein FG09482.1 [Gibberella zeae PH-1], gi\|42553364\|gb\|E...	222.0	[0..6]	[350..2]
gi\|30016920 - gi\|30016920\|gb\|AAP03992.1\| glyoxalase I [Paracoccidioides brasiliensis]	221.0	[0..8]	[351..2]
gi\|116202059, gi... - gi\|88177432\|gb\|EAQ84900.1\| hypothetical protein CHGG_08914 [Chaetomium globosum CBS 148.51], gi\|1162...	218.0	[0..6]	[350..2]

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Predicted Domain #1

Region A:
Residues: [1-167]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQEISNLVK KYNVTWQQTM LRIYDPKETV EFYEKNFGMI NIHTYHFNEY NFSLYFLITP  60
   61 PYDEEERKKL PEPNTKESEK YLWNLNTVCL ELTYNHNSQE KLSNGNNEND RGFGHIAFNC 120
  121 NDVIEQCDNL FKKNVKFHKL PHETKMKTIG FALDPNNYWI EIVKRSN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.39794
Match:	1f9zA
Description:	Glyoxalase I (lactoylglutathione lyase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
lactoylglutathione lyase activity	3.91334658149719	bayes_pls_golite062009
binding	1.68530537296561	bayes_pls_golite062009
carbon-sulfur lyase activity	1.44168339433372	bayes_pls_golite062009
catalytic activity	1.21778090213032	bayes_pls_golite062009
protein binding	0.28912087714501	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	0.0991913830827656	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [168-282]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVKWKNYKNI TNFSQTMIRV KNPEKSLYFY IHILGMKLIH VKHCSDFSLY FLKSNYACAE  60
   61 NNKEMIEDQS NKNTNEIYDF NSLKNSYQTD EDYENFKQSW EPVLELTHNH GTEDD

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	5.19
Match:	1f9zA
Description:	Glyoxalase I (lactoylglutathione lyase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
lactoylglutathione lyase activity	3.28975990186455	bayes_pls_golite062009
binding	1.71750599200046	bayes_pls_golite062009
catalytic activity	1.13770612627414	bayes_pls_golite062009
carbon-sulfur lyase activity	0.978794605325417	bayes_pls_golite062009
protein binding	0.308325217220065	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [283-356]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNFSYHNGNT EPRGFGHIGF LVNDLENYCK ELETLNVTFK KKVTEGLMKN IAFIYDPDNY  60
   61 VIELIQRDTS FIAK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.154902
Match:	1froA
Description:	Glyoxalase I (lactoylglutathione lyase)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: