YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|25300312
Organism:	Yersinia pestis
Length:	240 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|25300312.

Description	E-value	Query Range	Subject Range
gi\|166205645, gi... - gi\|166213347\|ref\|ZP_02239382.1\| phosphate transport system regulatory protein PhoU [Yersinia pestis ... gi\|167401532, gi... - gi\|167401532\|ref\|ZP_02307026.1\| phosphate transport system regulatory protein PhoU [Yersinia pestis ... gi\|167425542, gi... - gi\|167425542\|ref\|ZP_02317295.1\| phosphate transport system regulatory protein PhoU [Yersinia pestis ... gi\|145601160, gi... - gi\|145601160\|ref\|YP_001165236.1\| transcriptional regulator PhoU [Yersinia pestis Pestoides F], gi\|14... gi\|186897478, gi... - gi\|186897478\|ref\|YP_001874590.1\| transcriptional regulator PhoU [Yersinia pseudotuberculosis PB1/+],... gi\|108782061, gi... - gi\|108810148\|ref\|YP_654064.1\| transcriptional regulator PhoU [Yersinia pestis Antiqua], gi\|108782061... Q663R6\|Q663R6_YERPS - Phosphate transport regulatory protein - Yersinia pseudotuberculosis gi\|51591525, gi\|... - gi\|51598243\|ref\|YP_072434.1\| transcriptional regulator PhoU [Yersinia pseudotuberculosis IP 32953], ... gi\|108814130, gi... - gi\|229904671\|ref\|ZP_04519782.1\| negative regulator of PhoR/PhoB two-component regulator [Yersinia pe... gi\|45443743, gi\|... - gi\|45443743\|ref\|NP_995282.1\| transcriptional regulator PhoU [Yersinia pestis biovar Microtus str. 91... gi\|22127995, gi\|... - gi\|22127995\|ref\|NP_671418.1\| transcriptional regulator PhoU [Yersinia pestis KIM], gi\|21961142\|gb\|AA... gi\|162419718, gi... - gi\|77634101\|ref\|ZP_00796209.1\| COG0704: Phosphate uptake regulator [Yersinia pestis Angola], gi\|1624... gi\|152962140, gi... - gi\|77630946\|ref\|ZP_00793532.1\| COG0704: Phosphate uptake regulator [Yersinia pseudotuberculosis IP 3... gi\|229700221, gi... - gi\|229896783\|ref\|ZP_04511946.1\| negative regulator of PhoR/PhoB two-component regulator [Yersinia pe...	5.0E-59	[1..240]	[1..240]
gi\|77977952, gi\|... - gi\|77977952\|ref\|ZP_00833389.1\| COG0704: Phosphate uptake regulator [Yersinia intermedia ATCC 29909],...	8.0E-59	[1..240]	[1..240]
gi\|77961808, gi\|... - gi\|77961808\|ref\|ZP_00825638.1\| COG0704: Phosphate uptake regulator [Yersinia mollaretii ATCC 43969],...	2.0E-58	[1..240]	[1..240]
gi\|238724196, gi... - gi\|77973792\|ref\|ZP_00829337.1\| COG0704: Phosphate uptake regulator [Yersinia frederiksenii ATCC 3364...	3.0E-58	[1..240]	[1..240]
PHOU_ENTCL - Phosphate-specific transport system accessory protein PhoU OS=Enterobacter cloacae GN=phoU PE=3 SV=1	3.0E-58	[1..240]	[1..240]
gi\|62182337, gi\|... - gi\|62182337\|ref\|YP_218754.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica ser... gi\|56415723, gi\|... - gi\|56415723\|ref\|YP_152798.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica ser... lcl\|NC_016856.1_... - [gene=phoU] [protein=transcriptional regulator PhoU] [protein_id=YP_005240120.1] [location=complemen... gi\|205331632, gi... - gi\|205331632\|gb\|EDZ18396.1\| phosphate transport system regulatory protein PhoU [Salmonella enterica ... gi\|168242073, gi... - gi\|205339007\|gb\|EDZ25771.1\| phosphate transport system regulatory protein PhoU [Salmonella enterica ... gi\|205350224, gi... - gi\|205350224\|gb\|EDZ36855.1\| phosphate transport system regulatory protein PhoU [Salmonella enterica ... gi\|195632487, gi... - gi\|195632487\|gb\|EDX50971.1\| phosphate transport system regulatory protein PhoU [Salmonella enterica ... gi\|161366336, gi... - gi\|161616972\|ref\|YP_001590937.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica... gi\|205325569, gi... - gi\|205325569\|gb\|EDZ13408.1\| phosphate transport system regulatory protein PhoU [Salmonella enterica ... gi\|206710879, gi... - gi\|207859076\|ref\|YP_002245727.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica... gi\|213052684 - gi\|213052684\|ref\|ZP_03345562.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica ... gi\|16762476 - gi\|16762476\|ref\|NP_458093.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica ser... gi\|214001311 - gi\|214001311\|ref\|ZP_03412046.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica ... gi\|224470177, gi... - gi\|224585649\|ref\|YP_002639448.1\| phosphate transport system regulatory protein [Salmonella enterica ... gi\|197939343, gi... - gi\|198244827\|ref\|YP_002217799.1\| phosphate transport system regulatory protein PhoU [Salmonella ente... gi\|200388264, gi... - gi\|200388264\|ref\|ZP_03214876.1\| phosphate transport system regulatory protein PhoU [Salmonella enter... gi\|204928454, gi... - gi\|204928454\|ref\|ZP_03219653.1\| phosphate transport system regulatory protein PhoU [Salmonella enter... gi\|205354563, gi... - gi\|205354563\|ref\|YP_002228364.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica... gi\|194712421, gi... - gi\|194736919\|ref\|YP_002116793.1\| phosphate transport system regulatory protein PhoU [Salmonella ente... gi\|197251471, gi... - gi\|197251471\|ref\|YP_002148788.1\| phosphate transport system regulatory protein PhoU [Salmonella ente... gi\|197264784, gi... - gi\|197264784\|ref\|ZP_03164858.1\| phosphate transport system regulatory protein PhoU [Salmonella enter... gi\|197364651, gi... - gi\|197364651\|ref\|YP_002144288.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica... gi\|205340502, gi... - gi\|205340502\|gb\|EDZ27266.1\| phosphate transport system regulatory protein PhoU [Salmonella enterica ... gi\|194404265, gi... - gi\|194445602\|ref\|YP_002043099.1\| phosphate transport system regulatory protein PhoU [Salmonella ente... gi\|194451489, gi... - gi\|194451489\|ref\|YP_002047882.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica... gi\|194457668, gi... - gi\|194471304\|ref\|ZP_03077288.1\| phosphate transport system regulatory protein PhoU [Salmonella enter... gi\|16422426, gi\|... - gi\|16767137\|ref\|NP_462752.1\| transcriptional regulator PhoU [Salmonella typhimurium LT2], gi\|1642242... gi\|29143964, gi\|... - gi\|29143964\|ref\|NP_807306.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica ser... gi\|16504781, gi\|... - gi\|25300313\|pir\|\|AF0956 phosphate transport system regulatory protein STY3930 [imported] - Salmonell...	6.0E-58	[1..240]	[1..240]
gi\|77958177, gi\|... - gi\|77958177\|ref\|ZP_00822215.1\| COG0704: Phosphate uptake regulator [Yersinia bercovieri ATCC 43970],...	8.0E-58	[1..240]	[1..240]
gi\|49613915, gi\|... - gi\|50123389\|ref\|YP_052556.1\| transcriptional regulator PhoU [Pectobacterium atrosepticum SCRI1043], ...	6.0E-57	[1..235]	[1..235]
gi\|67845242 - gi\|67845242\|emb\|CAH41987.1\| phosphate regulon repressor protein [Erwinia amylovora]	7.0E-57	[1..237]	[1..237]
gi\|209158028, gi... - gi\|209396628\|ref\|YP_002273247.1\| phosphate transport system regulatory protein PhoU [Escherichia col... gi\|217321734, gi... - gi\|217325513\|ref\|ZP_03441597.1\| phosphate transport system regulatory protein PhoU [Escherichia coli... gi\|254595122, gi... - gi\|254795722\|ref\|YP_003080559.1\| negative regulator of PhoR/PhoB two-component regulator [Escherichi... gi\|218702570, gi... - gi\|218702570\|ref\|YP_002410199.1\| transcriptional regulator PhoU [Escherichia coli IAI39], gi\|2183725... gi\|218707366, gi... - gi\|218707366\|ref\|YP_002414885.1\| transcriptional regulator PhoU [Escherichia coli UMN026], gi\|218434... gi\|209753972, gi... - pir\|\|D91211 hypothetical protein ECs4660 [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|189002565, gi... - gi\|189002565\|gb\|EDU71551.1\| phosphate transport system regulatory protein PhoU [Escherichia coli O15... gi\|189373287, gi... - gi\|189373287\|gb\|EDU91703.1\| phosphate transport system regulatory protein PhoU [Escherichia coli O15... gi\|12518568, gi\|... - gi\|15804317\|ref\|NP_290356.1\| transcriptional regulator PhoU [Escherichia coli O157:H7 EDL933], gi\|12... gi\|168798763, gi... - gi\|189378751\|gb\|EDU97167.1\| phosphate transport system regulatory protein PhoU [Escherichia coli O15... gi\|15833914, gi\|... - gi\|15833914\|ref\|NP_312687.1\| PhoU [Escherichia coli O157:H7], gi\|13364135\|dbj\|BAB38083.1\| phosphate ... gi\|170683229, gi... - gi\|170683229\|ref\|YP_001746050.1\| phosphate transport system regulatory protein PhoU [Escherichia col... gi\|15833914, gi\|... - gi\|15833914\|ref\|NP_312687.1\| transcriptional regulator PhoU [Escherichia coli O157:H7 str. Sakai], g... gi\|195936346 - gi\|195936346\|ref\|ZP_03081728.1\| transcriptional regulator PhoU [Escherichia coli O157:H7 str. EC4024... gi\|208728055, gi... - gi\|208808254\|ref\|ZP_03250591.1\| phosphate transport system regulatory protein PhoU [Escherichia coli... gi\|208735078, gi... - gi\|208813801\|ref\|ZP_03255130.1\| phosphate transport system regulatory protein PhoU [Escherichia coli... gi\|208738876, gi... - gi\|208818753\|ref\|ZP_03259073.1\| phosphate transport system regulatory protein PhoU [Escherichia coli... gi\|168748556, gi... - gi\|188016904\|gb\|EDU55026.1\| phosphate transport system regulatory protein PhoU [Escherichia coli O15... gi\|194431306, gi... - gi\|83571513\|ref\|ZP_00922953.1\| COG0704: Phosphate uptake regulator [Shigella dysenteriae 1012], gi\|1... gi\|189358849, gi... - gi\|189358849\|gb\|EDU77268.1\| phosphate transport system regulatory protein PhoU [Escherichia coli O15... gi\|81243234, gi\|... - gi\|82779086\|ref\|YP_405435.1\| transcriptional regulator PhoU [Shigella dysenteriae Sd197], gi\|8124323... gi\|168759915, gi... - gi\|189369801\|gb\|EDU88217.1\| phosphate transport system regulatory protein PhoU [Escherichia coli O15... gi\|168766215, gi... - gi\|189364683\|gb\|EDU83102.1\| phosphate transport system regulatory protein PhoU [Escherichia coli O15... gi\|168772237, gi... - gi\|187771433\|gb\|EDU35277.1\| phosphate transport system regulatory protein PhoU [Escherichia coli O15...	9.0E-57	[1..240]	[1..240]

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Predicted Domain #1

Region A:
Residues: [1-240]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNLNLNKHI SGQFNAELEH IRTQVLTMGG LVEQQLSDAI TAMHNQDGEL AKRVIDGDEK  60
   61 VNMMEVAIDE ACVRIIAKRQ PTASDLRLVM AIIKTISELE RIGDVADKIC RTALEKFSHQ 120
  121 HQSLLVSLES LGRHTVQMLH DVLDAFARMD LDEAIRIYRE DRKVDQEYEG IVRQLMTYMM 180
  181 EDPRTIPSVL TALFCARSIE RIGDRCQNIC EFIFYFVKGH DFRHLGGDDL EKLLSGKPEK 240
  241

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.39794
Match:	1t72A
Description:	Crystal structure of phosphate transport system protein phoU from Aquifex aeolicus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.52706367695557	bayes_pls_golite062009
nucleic acid binding	1.40207651011289	bayes_pls_golite062009
DNA binding	1.39485368870356	bayes_pls_golite062009
transcription factor activity	1.27583598395229	bayes_pls_golite062009
binding	0.775039544296942	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: