YRC Public Data Repository - Protein Structure Prediction

Protein:	TIG_YERPS
Organism:	Yersinia pseudotuberculosis IP 32953
Length:	434 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIG_YERPS.

Description	E-value	Query Range	Subject Range
gi\|238729046, gi... - gi\|77979392\|ref\|ZP_00834811.1\| COG0544: FKBP-type peptidyl-prolyl cis-trans isomerase (trigger facto...	0.0	[1..434]	[1..434]
gi\|238788007, gi... - gi\|77974304\|ref\|ZP_00829845.1\| COG0544: FKBP-type peptidyl-prolyl cis-trans isomerase (trigger facto...	0.0	[1..434]	[1..434]
TIG_SODGM - Trigger factor OS=Sodalis glossinidius (strain morsitans) GN=tig PE=3 SV=1	0.0	[1..434]	[1..434]
gi\|238715488, gi... - gi\|77956938\|ref\|ZP_00821010.1\| COG0544: FKBP-type peptidyl-prolyl cis-trans isomerase (trigger facto...	0.0	[1..434]	[1..434]
gi\|77962965, gi\|... - gi\|77962965\|ref\|ZP_00826780.1\| COG0544: FKBP-type peptidyl-prolyl cis-trans isomerase (trigger facto...	0.0	[1..434]	[1..434]
gi\|66472064 - gi\|66472064\|dbj\|BAD98926.1\| trigger factor tag [Expression vector pColdTF]	0.0	[1..434]	[12..445]
TIG_PECAS - Trigger factor OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) GN=tig PE=3 SV=1 TIG_ERWCT - Trigger factor OS=Erwinia carotovora subsp. atroseptica GN=tig PE=3 SV=1	0.0	[1..434]	[1..434]
gi\|83727602, gi\|... - gi\|83745912\|ref\|ZP_00942969.1\| Trigger factor, ppiase [Ralstonia solanacearum UW551], gi\|83727602\|gb...	0.0	[1..433]	[58..504]
TIG_HAEI8 - Trigger factor OS=Haemophilus influenzae (strain 86-028NP) GN=tig PE=3 SV=1 gi\|42630976 - gi\|42630976\|ref\|ZP_00156514.1\| COG0544: FKBP-type peptidyl-prolyl cis-trans isomerase (trigger facto...	0.0	[1..432]	[1..432]
gi\|46128891 - gi\|46128891\|ref\|ZP_00154524.2\| COG0544: FKBP-type peptidyl-prolyl cis-trans isomerase (trigger facto...	0.0	[1..432]	[1..432]

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Predicted Domain #1

Region A:
Residues: [1-434]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVSVETTQG LGRRVTITVA ADSIEKAVKS ELVKAAKNVR IDGFRKGHVP MNIVEQRYGA  60
   61 SVRQDVLGDL MQRNFVDAII KEKINPAGAP NYVPGEYKQG EDFTYSVEFE VYPEVELKDL 120
  121 ESIEVEKPVV EVNDADVDTM LETLRKQQAT WKETDAAATA EDRATLDFTG SIDGEEFEGG 180
  181 KATDFVLAMG QGRMIPGFEE GVIGHKAGEE FTIDVNFPED YHAENLKGKS AKFAIVLKKV 240
  241 EVRELPELTE EFIKRFGVAD GSLAGLRAEV RKNMERELKG AVRNRVKTQA IDGLVSANNI 300
  301 DVPTALVDGE IDVLRRQAAQ RFGGNEKQAA ELPRELFEEQ AKRRVVVGLL LGEVISQHEL 360
  361 KADEDRVKAL IEEMASAYED PQEVIEFYSK NKELMNNMRN VALEEQAVET LLAKAKVTEK 420
  421 PTTFSELMNQ TTAA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	101.0
Match:	1w26A
Description:	Trigger Factor in Complex with the Ribosome forms a Molecular Cradle for Nascent Proteins
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidyl-prolyl cis-trans isomerase activity	4.0615867467963	bayes_pls_golite062009
cis-trans isomerase activity	3.99265212272703	bayes_pls_golite062009
isomerase activity	2.31710030777753	bayes_pls_golite062009
macrolide binding	1.71427500929512	bayes_pls_golite062009
FK506 binding	1.49236065710546	bayes_pls_golite062009
catalytic activity	0.885282592863018	bayes_pls_golite062009
protein binding	0.435609235063535	bayes_pls_golite062009
binding	0.3989771181671	bayes_pls_golite062009
drug binding	0.386165046836496	bayes_pls_golite062009
unfolded protein binding	0.27473817613726	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: