YRC Public Data Repository - Protein Structure Prediction

Protein:	FADR_ECOLI
Organism:	Escherichia coli
Length:	239 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FADR_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|52081972, gi\|... - gi\|52787360\|ref\|YP_093189.1\| YvfI [Bacillus licheniformis ATCC 14580], gi\|52349862\|gb\|AAU42496.1\| Yv...	176.0	[0..3]	[229..6]
gi\|134300031, gi... - gi\|88945080\|ref\|ZP_01148300.1\| regulatory protein GntR, HTH [Desulfotomaculum reducens MI-1], gi\|889...	175.0	[0..3]	[230..6]
gi\|77359356, gi\|... - gi\|77359356\|ref\|YP_338931.1\| transcriptional regulator PdhR [Pseudoalteromonas haloplanktis TAC125],...	174.0	[0..1]	[239..3]
gi\|56420550, gi\|... - gi\|56420550\|ref\|YP_147868.1\| transcriptional regulator [Geobacillus kaustophilus HTA426], gi\|5638039...	173.0	[0..3]	[223..17]
gi\|27367455, gi\|... - gi\|27367455\|ref\|NP_762982.1\| transcriptional regulator [Vibrio vulnificus CMCP6], gi\|27359024\|gb\|AAO... gi\|37201794, gi\|... - gi\|37677249\|ref\|NP_937645.1\| transcriptional regulator [Vibrio vulnificus YJ016], gi\|37201794\|dbj\|BA...	173.0	[0..1]	[235..10]
gi\|150391479, gi... - gi\|77686091\|ref\|ZP_00801461.1\| regulatory protein GntR, HTH:GntR, C-terminal [Alkaliphilus metallire...	172.0	[0..3]	[223..5]
gi\|89081562, gi\|... - gi\|89094087\|ref\|ZP_01167030.1\| transcriptional regulator of pyruvate dehydrogenase complex [Oceanosp...	172.0	[0..3]	[239..6]
gi\|39983607, gi\|... - gi\|39996726\|ref\|NP_952677.1\| GntR family transcriptional regulator [Geobacter sulfurreducens PCA], g...	170.0	[0..3]	[222..6]
gi\|90309525, gi\|... - gi\|90409369\|ref\|ZP_01217453.1\| Transcriptional regulator [Psychromonas sp. CNPT3], gi\|90309525\|gb\|EA...	170.0	[0..4]	[235..5]

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Predicted Domain #1

Region A:
Residues: [1-239]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVIKAQSPAG FAEEYIIESI WNNRFPPGTI LPAERELSEL IGVTRTTLRE VLQRLARDGW  60
   61 LTIQHGKPTK VNNFWETSGL NILETLARLD HESVPQLIDN LLSVRTNIST IFIRTAFRQH 120
  121 PDKAQEVLAT ANEVADHADA FAELDYNIFR GLAFASGNPI YGLILNGMKG LYTRIGRHYF 180
  181 ANPEARSLAL GFYHKLSALC SEGAHDQVYE TVRRYGHESG EIWHRMQKNL PGDLAIQGR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.30103
Match:	1hw1A
Description:	Fatty acid responsive transcription factor FadR, N-terminal domain; Fatty acid responsive transcription factor FadR, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.56369131794526	bayes_pls_golite062009
nucleic acid binding	1.49794573374102	bayes_pls_golite062009
DNA binding	1.47042497151354	bayes_pls_golite062009
transcription factor activity	1.32068126067873	bayes_pls_golite062009
protein binding	1.08567463180852	bayes_pls_golite062009
binding	0.905540801797993	bayes_pls_golite062009
sequence-specific DNA binding	0.53285802828572	bayes_pls_golite062009
transcription activator activity	0.41507957082843	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: