YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|16762830
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. CT18
Length:	272 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|16762830.

Description	E-value	Query Range	Subject Range
gi\|53797045 - ref\|ZP_00357923.1\| COG0545: FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Chloroflexus aurantiac... gi\|222448091, gi... - gi\|222524212\|ref\|YP_002568683.1\| peptidylprolyl isomerase FKBP-type [Chloroflexus sp. Y-400-fl], gi\|... gi\|163667727, gi... - gi\|76261334\|ref\|ZP_00768948.1\| Peptidylprolyl isomerase, FKBP-type [Chloroflexus aurantiacus J-10-fl...	9.0E-56	[22..248]	[2..236]
gi\|2231720 - gi\|2231720\|gb\|AAC45693.1\| macrophage infectivity potentiator [Legionella jordanis]	2.0E-54	[1..252]	[1..250]
gi\|110616728, gi... - gi\|110807180\|ref\|YP_690700.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Shigella flexneri 5 str... gi\|24053810, gi\|... - gi\|24114611\|ref\|NP_709121.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Shigella flexneri 2a str... gi\|30065367, gi\|... - gi\|30065367\|ref\|NP_839538.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Shigella flexneri 2a str...	4.0E-54	[1..259]	[1..259]
gi\|209756942, gi... - pir\|\|F91153 FKBP-type peptidyl-prolyl cis-trans isomerase [imported] - Escherichia coli (strain O157... FKBA_ECOL6 - FKBP-type peptidyl-prolyl cis-trans isomerase FkpA OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 7... gi\|168753103, gi... - gi\|189359191\|gb\|EDU77610.1\| FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [Escherichia coli O15... gi\|188014187, gi... - gi\|188014187\|gb\|EDU52309.1\| FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [Escherichia coli O15... gi\|218697026, gi... - gi\|218697026\|ref\|YP_002404693.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Escherichia coli 559... gi\|218560408, gi... - gi\|218560408\|ref\|YP_002393321.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Escherichia coli S88... gi\|91212823, gi\|... - gi\|91212823\|ref\|YP_542809.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Escherichia coli UTI89],... gi\|218706941, gi... - gi\|218706941\|ref\|YP_002414460.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Escherichia coli UMN... gi\|13363671, gi\|... - gi\|15833452\|ref\|NP_312225.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Escherichia coli O157:H7... gi\|218702095, gi... - gi\|218702095\|ref\|YP_002409724.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Escherichia coli IAI... gi\|193061860, gi... - gi\|75260363\|ref\|ZP_00731631.1\| COG0545: FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Escherichi... gi\|188493036, gi... - gi\|188493036\|ref\|ZP_03000306.1\| FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [Escherichia coli... gi\|74313853, gi\|... - gi\|74313853\|ref\|YP_312272.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Shigella sonnei Ss046], ... gi\|170680696, gi... - gi\|170680696\|ref\|YP_001745595.1\| FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [Escherichia col... gi\|194430698, gi... - gi\|75207903\|ref\|ZP_00708356.1\| COG0545: FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Escherichi... gi\|208814429, gi... - gi\|208814429\|ref\|ZP_03255758.1\| FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [Escherichia coli... gi\|191171482, gi... - gi\|75241558\|ref\|ZP_00725403.1\| COG0545: FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Escherichi... gi\|195934843 - gi\|195934843\|ref\|ZP_03080225.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Escherichia coli O157... FKBA_ECOL6 - FKBP-type peptidyl-prolyl cis-trans isomerase fkpA OS=Escherichia coli O6 GN=fkpA PE=3 SV=1 gi\|209914058, gi... - gi\|209920799\|ref\|YP_002294883.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Escherichia coli SE1... FKBA_ECO57 - FKBP-type peptidyl-prolyl cis-trans isomerase FkpA OS=Escherichia coli O157:H7 GN=fkpA PE=3 SV=1 gi\|209397438, gi... - gi\|209397438\|ref\|YP_002272789.1\| FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [Escherichia col... gi\|81247107, gi\|... - gi\|82545696\|ref\|YP_409643.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Shigella boydii Sb227], ... gi\|218555891, gi... - gi\|218555891\|ref\|YP_002388804.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Escherichia coli IAI... gi\|217320648, gi... - gi\|217324427\|ref\|ZP_03440511.1\| FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [Escherichia coli... gi\|157157129, gi... - gi\|75188122\|ref\|ZP_00701389.1\| COG0545: FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Escherichi... gi\|157162823, gi... - gi\|75197279\|ref\|ZP_00707349.1\| COG0545: FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Escherichi... gi\|115514749, gi... - gi\|117625625\|ref\|YP_858948.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Escherichia coli APEC O... gi\|227883481, gi... - gi\|227883481\|ref\|ZP_04001286.1\| peptidylprolyl isomerase [Escherichia coli 83972], gi\|227839360\|gb\|E... gi\|226902342, gi... - gi\|237703078\|ref\|ZP_04533559.1\| peptidyl-prolyl cis-trans isomerase fkpA [Escherichia sp. 3_2_53FAA]... gi\|242378873, gi... - gi\|251786600\|ref\|YP_003000904.1\| hypothetical protein B21_03149 [Escherichia coli BL21], gi\|24237887... gi\|254290025, gi... - gi\|254290025\|ref\|YP_003055773.1\| FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) [Escherich... gi\|254163275, gi... - gi\|254163275\|ref\|YP_003046383.1\| FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) [Escherich... gi\|254594670, gi... - gi\|254795270\|ref\|YP_003080107.1\| FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) [Escherich...	4.0E-54	[1..259]	[1..259]
gi\|187428304, gi... - gi\|75180040\|ref\|ZP_00700027.1\| COG0545: FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Shigella b...	6.0E-54	[1..259]	[1..259]
gi\|12517968, gi\|... - gi\|15803860\|ref\|NP_289894.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Escherichia coli O157:H7... gi\|25358304 - gi\|25358304\|pir\|\|B85999 hypothetical protein fkpA [imported] - Escherichia coli (strain O157:H7, su...	3.0E-53	[1..259]	[1..259]
gi\|27364730, gi\|... - gi\|27364730\|ref\|NP_760258.1\| FKBP-type peptidyl-prolyl cis-trans isomerase 1 [Vibrio vulnificus CMCP...	4.0E-53	[1..255]	[1..260]
gi\|37199972, gi\|... - gi\|37681221\|ref\|NP_935830.1\| FKBP-type peptidyl-prolyl cis-trans isomerase 1 [Vibrio vulnificus YJ01...	5.0E-53	[1..255]	[5..264]
gi\|110643588, gi... - gi\|110643588\|ref\|YP_671318.1\| FKBP-type peptidyl-prolyl cis-trans isomerase [Escherichia coli 536], ...	7.0E-53	[1..259]	[1..259]
gi\|2231736 - gi\|2231736\|gb\|AAC45701.1\| macrophage infectivity potentiator [Legionella parisiensis]	1.0E-52	[18..251]	[4..232]

Back

Predicted Domain #1

Region A:
Residues: [1-272]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSLFKATLL ATTMAVAMHV PITFAADAAK PAATADSKAA FKNDDQKAAY ALGASLGRYM  60
   61 ENSLKEQEKL GIKLDKDQLI AGVQDAFADK SKLSDQEIEQ TLQTFEARVK SAAQAKMEKD 120
  121 AADNEAKGKT FRDAFAKEKG VKTSSTGLLY KVEKEGTGEA PKDSDTVVVN YKGTLIDGKE 180
  181 FDNSYTRGEP LSFRLDGVIP GWTEGLKNIK KSGKIKLVIP PALAYGKTGV PGIPANSTLV 240
  241 FDVELLDIKP APKADAKPAD AADAKAADAA KK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.39794
Match:	1q6uA
Description:	Crystal structure of FkpA from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidyl-prolyl cis-trans isomerase activity	4.0615867467963	bayes_pls_golite062009
cis-trans isomerase activity	3.99265212272703	bayes_pls_golite062009
isomerase activity	2.31710030777753	bayes_pls_golite062009
macrolide binding	1.71427500929512	bayes_pls_golite062009
FK506 binding	1.49236065710546	bayes_pls_golite062009
binding	1.0388665941536	bayes_pls_golite062009
catalytic activity	0.885282592863018	bayes_pls_golite062009
transcription regulator activity	0.476979076197416	bayes_pls_golite062009
unfolded protein binding	0.27473817613726	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: