| Protein: | nhr-66 |
| Organism: | Caenorhabditis elegans |
| Length: | 659 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-66.
| Description | E-value | Query Range |
Subject Range |
|
|
396.0 | [0..1] | [655..274] |
|
Region A: Residues: [1-187] |
1 11 21 31 41 51
| | | | | |
1 MTPQIGLTGL GSLTSLPPEL LLQFARLDGF NLLPAVGSPA IPSSSSCSEP STSQASTVVS 60
61 APTLPPPSPL TSLPQKPAPL MPSGHVTTVD QQNRQQHQQQ QRQQQQAQQQ NSMARKYSMD 120
121 TIQHHTMQHP HQLQYIPNHF MTASTDVFAA MDMSQKQSSP PGIFKIVAAK NEPSSSSNSQ 180
181 PGTPAMG
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [188-317] |
1 11 21 31 41 51
| | | | | |
1 DRRAVPACAI CGTDSTGIHF GVDACAACSA FFRRTVVLNK DYSCNKGGKC TVVKDGSAGQ 60
61 KCRACRFRKC ISSGMDKNSV QHRRDAIGKY SAGVKRELSP DAEFEPSAKV STVSEPSTSS 120
121 GPSGGFNQNV
|
| Detection Method: | |
| Confidence: | 27.0 |
| Match: | 2a66A |
| Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [318-659] |
1 11 21 31 41 51
| | | | | |
1 SSPAGIPRVP STLRTTQAST CMNSACGQKS VLHELICRQN FLTEQRQLFY AGCLGDWFRK 60
61 PSSIENQTLS ELTDFSSCMF HLWKIEPRLA ADFMNRNRYL DPLPIVEKLK IYRNFVIMRQ 120
121 SVEEPYLTWR HGGLEKRWFV MPNNTYIDFN NIAKYFENGA LKDLKLDYET TTNLFLPSFT 180
181 HAMDTIGEKM KKNNITETEL TILLGLVLLD PGIYGIHEST RKFLKRIRDQ LIHDVYMYYE 240
241 DEMSHLYDPE IRMADIFMLV AAIKIHSIKT SENMHMLRVF DLIPADACFN QMLDVESVNV 300
301 SPDGQKDSEA EQGPSPVSVP EAARGSYQDD DMPPVLEKNC DL
|
| Detection Method: | |
| Confidence: | 45.522879 |
| Match: | 1xdkB |
| Description: | Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.31508164334985 | bayes_pls_golite062009 |
| transcription regulator activity | 2.02157665604796 | bayes_pls_golite062009 |
| DNA binding | 1.47175550190876 | bayes_pls_golite062009 |
| signal transducer activity | 1.430912689846 | bayes_pls_golite062009 |
| molecular transducer activity | 1.430912689846 | bayes_pls_golite062009 |
| protein binding | 1.34648900580465 | bayes_pls_golite062009 |
| nucleic acid binding | 1.29377568150934 | bayes_pls_golite062009 |
| receptor activity | 1.17902442273252 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 1.16718542519809 | bayes_pls_golite062009 |
| transcription activator activity | 0.96843436755116 | bayes_pls_golite062009 |
| transcription factor activity | 0.92060883178562 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.67007540744134 | bayes_pls_golite062009 |
