YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|11356241
Organism:	Vibrio cholerae
Length:	253 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|11356241.

Description	E-value	Query Range	Subject Range
gi\|254229357, gi... - gi\|75855918\|ref\|ZP_00763557.1\| COG1349: Transcriptional regulators of sugar metabolism [Vibrio sp. E...	230.0	[0..1]	[253..1]
gi\|91191480, gi\|... - gi\|91223394\|ref\|ZP_01258659.1\| transcriptional regulator, DeoR family protein [Vibrio alginolyticus ...	230.0	[0..1]	[253..1]
gi\|89074567, gi\|... - gi\|89074567\|ref\|ZP_01161039.1\| transcriptional regulator, DeoR family protein [Photobacterium sp. SK...	230.0	[0..1]	[253..1]
gi\|90579042, gi\|... - gi\|90579042\|ref\|ZP_01234852.1\| transcriptional regulator, DeoR family protein [Vibrio angustum S14],...	229.0	[0..1]	[253..1]
gi\|37199558, gi\|... - gi\|37680809\|ref\|NP_935418.1\| transcriptional regulator of sugar metabolism [Vibrio vulnificus YJ016]...	227.0	[0..2]	[252..11]
tr\|A0A085Q0T6\|A0... - Glycerol-3-phosphate regulon repressor OS=Vibrio cholerae GN=glpR PE=4 SV=1, Transcriptional regulat... gi\|227015587, gi... - gi\|75825205\|ref\|ZP_00754641.1\| COG1349: Transcriptional regulators of sugar metabolism [Vibrio chole... gi\|75823823, gi\|... - gi\|75823823\|ref\|ZP_00753302.1\| COG1349: Transcriptional regulators of sugar metabolism [Vibrio chole... gi\|75817054, gi\|... - gi\|75817054\|ref\|ZP_00747509.1\| COG1349: Transcriptional regulators of sugar metabolism [Vibrio chole... gi\|125622817, gi... - gi\|75821039\|ref\|ZP_00751075.1\| COG1349: Transcriptional regulators of sugar metabolism [Vibrio chole... gi\|197753768, gi... - gi\|254284566\|ref\|ZP_04959533.1\| transcriptional regulator, DeoR family [Vibrio cholerae AM-19226], g... gi\|153824784, gi... - gi\|153824784\|ref\|ZP_01977451.1\| transcriptional regulator, DeoR family [Vibrio cholerae MZO-2], gi\|1... gi\|229356271, gi... - gi\|229505920\|ref\|ZP_04395429.1\| glycerol-3-phosphate regulon repressor DeoR family [Vibrio cholerae ... gi\|227011648, gi... - gi\|227812506\|ref\|YP_002812516.1\| transcriptional regulator, DeoR family [Vibrio cholerae M66-2], gi\|... gi\|229526509, gi... - gi\|229526509\|ref\|ZP_04415913.1\| glycerol-3-phosphate regulon repressor DeoR family [Vibrio cholerae ... gi\|229340450, gi... - gi\|229522465\|ref\|ZP_04411881.1\| glycerol-3-phosphate regulon repressor DeoR family [Vibrio cholerae ... gi\|121549083, gi... - gi\|121586655\|ref\|ZP_01676439.1\| transcriptional regulator, DeoR family [Vibrio cholerae 2740-80], gi... gi\|229334522, gi... - gi\|229528160\|ref\|ZP_04417551.1\| glycerol-3-phosphate regulon repressor DeoR family [Vibrio cholerae ... gi\|153801403, gi... - gi\|153801403\|ref\|ZP_01955989.1\| transcriptional regulator, DeoR family [Vibrio cholerae MZO-3], gi\|1... gi\|153217123, gi... - gi\|153217123\|ref\|ZP_01950887.1\| transcriptional regulator, DeoR family [Vibrio cholerae 1587], gi\|12... gi\|153818309, gi... - gi\|153818309\|ref\|ZP_01970976.1\| transcriptional regulator, DeoR family [Vibrio cholerae NCTC 8457], ...	227.0	[0..1]	[253..1]
gi\|28899161, gi\|... - gi\|28899161\|ref\|NP_798766.1\| DeoR family transcriptional regulator [Vibrio parahaemolyticus RIMD 221... gi\|28807385 - gi\|28807385\|dbj\|BAC60650.1\| transcriptional regulator, DeoR family [Vibrio parahaemolyticus RIMD 221... gi\|149749939, gi... - gi\|153836793\|ref\|ZP_01989460.1\| transcriptional regulator, DeoR family [Vibrio parahaemolyticus AQ38...	227.0	[0..1]	[253..1]
gi\|77978684, gi\|... - gi\|77978684\|ref\|ZP_00834110.1\| COG1349: Transcriptional regulators of sugar metabolism [Yersinia int...	225.0	[0..1]	[252..1]
gi\|255054070, gi... - gi\|255054070\|ref\|ZP_05306318.1\| transcriptional regulator, DeoR family [Pectobacterium wasabiae WPP1... gi\|253690290, gi... - gi\|253690290\|ref\|YP_003019480.1\| transcriptional regulator, DeoR family [Pectobacterium carotovorum ... gi\|50123057, gi\|... - gi\|50123057\|ref\|YP_052224.1\| DNA-binding transcriptional repressor GlpR [Pectobacterium atrosepticum...	225.0	[0..1]	[252..1]
gi\|54307380, gi\|... - gi\|54307380\|ref\|YP_128400.1\| putative glycerol-3-phosphate repressor protein [Photobacterium profund...	224.0	[0..1]	[253..1]

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Predicted Domain #1

Region A:
Residues: [1-63]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKAVKRHQEI IELVQAQGFV STEELVERFD VSPQTIRRDL NELAEANKLR RNHGGATIAT  60
   61 SSE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	6.30103
Match:	2p5vA
Description:	No description for 2p5vA was found.

Predicted Domain #2

Region A:
Residues: [64-253]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSSYHTRQVS YQNEKEKVAM ALVQHIPDGA TLFIDIGTTP EAIARALMVN HHQLRVVTNN  60
   61 LNVATMLMSK PDFSIILAGG EVRNKDGGVT GEATLDFISQ FRLDFGILGI SGIDYDGSLL 120
  121 DFDYHEVRVK RAIIENSRSV FLAVDHSKFG RNAMVKLGTL ADVDLVITDQ TPPKEIEAFA 180
  181 KENEVTIQVV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.221849
Match:	1lk5A
Description:	D-ribose-5-phosphate isomerase (RpiA), catalytic domain; D-ribose-5-phosphate isomerase (RpiA), lid domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleic acid binding	0.965520574888216	bayes_pls_golite062009
catalytic activity	0.795398981330566	bayes_pls_golite062009
transcription regulator activity	0.769423781192988	bayes_pls_golite062009
DNA binding	0.223734115868557	bayes_pls_golite062009
binding	0.199466104892993	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: