YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|11269598
Organism:	Vibrio cholerae
Length:	213 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|11269598.

Description	E-value	Query Range	Subject Range
gi\|27366367, gi\|... - gi\|27366367\|ref\|NP_761895.1\| endonuclease III [Vibrio vulnificus CMCP6], gi\|27362568\|gb\|AAO11422.1\|A...	255.0	[0..1]	[213..1]
gi\|37679370, gi\|... - gi\|37679370\|ref\|NP_933979.1\| EndoIII-related endonuclease [Vibrio vulnificus YJ016], gi\|37198113\|dbj...	254.0	[0..1]	[213..1]
tr\|A0A085R1X0\|A0... - Endonuclease III OS=Vibrio cholerae GN=nth PE=3 SV=1 gi\|121628275, gi... - gi\|75814531\|ref\|ZP_00745107.1\| COG0177: Predicted EndoIII-related endonuclease [Vibrio cholerae V52]... gi\|227012828, gi... - gi\|75826318\|ref\|ZP_00755753.1\| COG0177: Predicted EndoIII-related endonuclease [Vibrio cholerae O395... gi\|229525624, gi... - gi\|229525624\|ref\|ZP_04415029.1\| endonuclease III [Vibrio cholerae bv. albensis VL426], gi\|229339205\|... gi\|229515397, gi... - gi\|229515397\|ref\|ZP_04404856.1\| A/G-specific adenine glycosylase [Vibrio cholerae TMA 21], gi\|229347...	252.0	[0..1]	[213..1]
gi\|28898882, gi\|... - gi\|28898882\|ref\|NP_798487.1\| endonuclease III [Vibrio parahaemolyticus RIMD 2210633], gi\|28807101\|db... gi\|28807101 - gi\|28807101\|dbj\|BAC60371.1\| endonuclease III [Vibrio parahaemolyticus RIMD 2210633]	252.0	[0..1]	[213..1]
gi\|91187535, gi\|... - gi\|91228904\|ref\|ZP_01262804.1\| endonuclease III [Vibrio alginolyticus 12G01], gi\|91187535\|gb\|EAS7386...	250.0	[0..1]	[213..1]
gi\|15602246, gi\|... - gi\|15602246\|ref\|NP_245318.1\| hypothetical protein PM0381 [Pasteurella multocida subsp. multocida str...	250.0	[0..1]	[209..1]
gi\|113461208, gi... - gi\|23467008\|ref\|ZP_00122593.1\| COG0177: Predicted EndoIII-related endonuclease [Haemophilus somnus 1... gi\|168825935, gi... - gi\|170717806\|ref\|YP_001784869.1\| endonuclease III [Haemophilus somnus 2336], gi\|168825935\|gb\|ACA3130...	250.0	[0..1]	[209..1]
gi\|126097154, gi... - gi\|126208362\|ref\|YP_001053587.1\| endonuclease III [Actinobacillus pleuropneumoniae L20], gi\|12609715... gi\|190150214, gi... - gi\|190150214\|ref\|YP_001968739.1\| endonuclease III [Actinobacillus pleuropneumoniae serovar 7 str. AP... gi\|32033526 - gi\|32033526\|ref\|ZP_00133853.1\| COG0177: Predicted EndoIII-related endonuclease [Actinobacillus pleur...	249.0	[0..1]	[208..1]
gi\|116183255, gi... - gi\|75853689\|ref\|ZP_00761472.1\| COG0177: Predicted EndoIII-related endonuclease [Vibrio sp. Ex25], gi...	248.0	[0..1]	[213..1]
gi\|108811869, gi... - gi\|229902171\|ref\|ZP_04517292.1\| DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III) [Yers... gi\|149292255, gi... - gi\|149365842\|ref\|ZP_01887877.1\| endonuclease III [Yersinia pestis CA88-4125], gi\|149292255\|gb\|EDM423... gi\|145598193, gi... - gi\|145598193\|ref\|YP_001162269.1\| endonuclease III [Yersinia pestis Pestoides F], gi\|145209889\|gb\|ABP... gi\|89102529, gi\|... - gi\|89103498\|ref\|ZP_01176072.1\| COG0177: Predicted EndoIII-related endonuclease [Yersinia pestis biov... Q66AH0\|Q66AH0_YERPS - Endonuclease III - Yersinia pseudotuberculosis gi\|108779506, gi... - gi\|108807593\|ref\|YP_651509.1\| endonuclease III [Yersinia pestis Antiqua], gi\|108779506\|gb\|ABG13564.1... gi\|21958913, gi\|... - gi\|22125970\|ref\|NP_669393.1\| endonuclease III [Yersinia pestis KIM], gi\|21958913\|gb\|AAM85644.1\|AE013... gi\|25292140 - pir\|\|AI0272 DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) [imported] - Yersinia pestis (s... gi\|186895536, gi... - gi\|186895536\|ref\|YP_001872648.1\| endonuclease III [Yersinia pseudotuberculosis PB1/+], gi\|186698562\|... gi\|51596486, gi\|... - gi\|51596486\|ref\|YP_070677.1\| endonuclease III [Yersinia pseudotuberculosis IP 32953], gi\|51589768\|em... gi\|45441837, gi\|... - gi\|45441837\|ref\|NP_993376.1\| endonuclease III [Yersinia pestis biovar Microtus str. 91001], gi\|45436... gi\|229702019, gi... - gi\|229894924\|ref\|ZP_04510102.1\| DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III) [Yers... gi\|115347946, gi... - gi\|218929335\|ref\|YP_002347210.1\| endonuclease III [Yersinia pestis CO92], gi\|16122467\|ref\|NP_405780.... gi\|229897667, gi... - gi\|229897667\|ref\|ZP_04512823.1\| DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III) [Yers... gi\|229688602, gi... - gi\|229898312\|ref\|ZP_04513459.1\| DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III) [Yers... gi\|165990463, gi... - gi\|166010761\|ref\|ZP_02231659.1\| endonuclease III [Yersinia pestis biovar Antiqua str. E1979001], gi\|... gi\|165920625, gi... - gi\|165927359\|ref\|ZP_02223191.1\| endonuclease III [Yersinia pestis biovar Orientalis str. F1991016], ... gi\|167400818, gi... - gi\|167400818\|ref\|ZP_02306324.1\| endonuclease III [Yersinia pestis biovar Antiqua str. UG05-0454], gi... gi\|166207872, gi... - gi\|166210692\|ref\|ZP_02236727.1\| endonuclease III [Yersinia pestis biovar Antiqua str. B42003004], gi... gi\|167056185, gi... - gi\|167424998\|ref\|ZP_02316751.1\| endonuclease III [Yersinia pestis biovar Mediaevalis str. K1973002],... gi\|167420201, gi... - gi\|167420201\|ref\|ZP_02311954.1\| endonuclease III [Yersinia pestis biovar Orientalis str. MG05-1020],... gi\|170024248, gi... - gi\|170024248\|ref\|YP_001720753.1\| endonuclease III [Yersinia pseudotuberculosis YPIII], gi\|169750782\|... gi\|167467741 - gi\|167467741\|ref\|ZP_02332445.1\| endonuclease III [Yersinia pestis FV-1] gi\|162352212, gi... - gi\|77636252\|ref\|ZP_00798328.1\| COG0177: Predicted EndoIII-related endonuclease [Yersinia pestis Ango... gi\|153948366, gi... - gi\|77629237\|ref\|ZP_00791823.1\| COG0177: Predicted EndoIII-related endonuclease [Yersinia pseudotuber...	248.0	[0..1]	[212..1]

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Predicted Domain #1

Region A:
Residues: [1-213]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNAKRIEIL ERLRAHNPKP ETELNWNSPF ELLIAVLLSA QATDVSVNKA TDKLYAVANT  60
   61 PQTMLDLGVD GVKEYIKTIG LFNSKAENVI KTCRILLEKH QGEVPEDREA LEALPGVGRK 120
  121 TANVVLNTAF GWPTIAVDTH IFRVSNRTKF AVGKNVDEVE HKLLKVVPNE FKLDVHHWLI 180
  181 LHGRYTCVAR KPRCGSCIIE DLCEFKDKVY PES

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.221849
Match:	2abkA
Description:	REFINEMENT OF THE NATIVE STRUCTURE OF ENDONUCLEASE III TO A RESOLUTION OF 1.85 ANGSTROM
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
DNA N-glycosylase activity	4.08559331236111	bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds	3.73234184319832	bayes_pls_golite062009
DNA-(apurinic or apyrimidinic site) lyase activity	3.12421941323765	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	2.54759386266723	bayes_pls_golite062009
catalytic activity	2.50389926428623	bayes_pls_golite062009
oxidized base lesion DNA N-glycosylase activity	1.80199518353554	bayes_pls_golite062009
alkylbase DNA N-glycosylase activity	1.75218522602775	bayes_pls_golite062009
hydrolase activity	1.39000450534744	bayes_pls_golite062009
DNA-3-methyladenine glycosylase I activity	1.14337995879633	bayes_pls_golite062009
oxidized purine base lesion DNA N-glycosylase activity	0.473206156100251	bayes_pls_golite062009
uracil DNA N-glycosylase activity	0.29478804124408	bayes_pls_golite062009
oxidized pyrimidine base lesion DNA N-glycosylase activity	0.253198605718519	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: