YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|9654950, gi\|1...
Organism:	Vibrio cholerae O1 biovar El Tor str. N16961
Length:	129 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|9654950, gi|1....

Description	E-value	Query Range	Subject Range
gi\|75825896 - gi\|75825896\|ref\|ZP_00755331.1\| COG1539: Dihydroneopterin aldolase [Vibrio cholerae O395] gi\|75829252, gi\|... - gi\|75829252\|ref\|ZP_00758562.1\| COG1539: Dihydroneopterin aldolase [Vibrio cholerae MO10], gi\|1161881... gi\|75815672 - gi\|75815672\|ref\|ZP_00746169.1\| COG1539: Dihydroneopterin aldolase [Vibrio cholerae V52]	149.0	[0..13]	[129..1]
gi\|75823728, gi\|... - gi\|75823728\|ref\|ZP_00753212.1\| COG1539: Dihydroneopterin aldolase [Vibrio cholerae RC385], gi\|116216... tr\|A0A085RGT4\|A0... - Dihydroneopterin aldolase OS=Vibrio cholerae GN=folB PE=4 SV=1	149.0	[0..13]	[129..1]
gi\|75818284, gi\|... - gi\|75818284\|ref\|ZP_00748469.1\| COG1539: Dihydroneopterin aldolase [Vibrio cholerae V51], gi\|11621902...	149.0	[0..13]	[129..1]
gi\|58583747, gi\|... - gi\|58583747\|ref\|YP_202763.1\| dihydroneopterin aldolase [Xanthomonas oryzae pv. oryzae KACC10331], gi...	148.0	[0..5]	[128..16]
gi\|149745162, gi... - gi\|153845021\|ref\|ZP_01993722.1\| dihydroneopterin aldolase [Vibrio parahaemolyticus AQ3810], gi\|14974... gi\|28805394 - gi\|28805394\|dbj\|BAC58674.1\| putative dihydroneopterin aldolase FolB [Vibrio parahaemolyticus RIMD 22... gi\|28897185, gi\|... - gi\|28897185\|ref\|NP_796790.1\| putative dihydroneopterin aldolase FolB [Vibrio parahaemolyticus RIMD 2...	148.0	[0..11]	[128..1]
gi\|27360202, gi\|... - gi\|27364084\|ref\|NP_759612.1\| dihydroneopterin aldolase [Vibrio vulnificus CMCP6], gi\|27360202\|gb\|AAO... gi\|37678752, gi\|... - gi\|37678752\|ref\|NP_933361.1\| dihydroneopterin aldolase [Vibrio vulnificus YJ016], gi\|37197493\|dbj\|BA...	148.0	[0..11]	[128..1]
gi\|150841262, gi... - gi\|75436806\|ref\|ZP_00733347.1\| dihydroneopterin aldolase [Actinobacillus succinogenes 130Z], gi\|7427...	148.0	[0..12]	[127..1]
gi\|91227151, gi\|... - gi\|91227151\|ref\|ZP_01261635.1\| putative dihydroneopterin aldolase FolB [Vibrio alginolyticus 12G01],...	147.0	[0..11]	[128..1]
gi\|66770185, gi\|... - gi\|66770185\|ref\|YP_244947.1\| dihydroneopterin aldolase [Xanthomonas campestris pv. campestris str. 8... gi\|21233243, gi\|... - gi\|21233243\|ref\|NP_639160.1\| dihydroneopterin aldolase [Xanthomonas campestris pv. campestris str. A...	146.0	[0..13]	[128..1]
gi\|205273902, gi... - gi\|205354121\|ref\|YP_002227922.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphat... lcl\|NC_016856.1_... - [gene=folB] [protein=bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimera... gi\|206710267, gi... - gi\|207858464\|ref\|YP_002245115.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphat... gi\|197364075, gi... - gi\|197364075\|ref\|YP_002143712.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphat... gi\|56415146, gi\|... - gi\|56415146\|ref\|YP_152221.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'... gi\|62129356, gi\|... - gi\|62181723\|ref\|YP_218140.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'... gi\|16766506, gi\|... - gi\|16766506\|ref\|NP_462121.1\| bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'...	145.0	[0..12]	[127..1]

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Predicted Domain #1

Region A:
Residues: [1-129]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGIRPVNRKR LSMDKVFIEQ LEVITTIGVY DWEQQIKQKL VLDLEMAHDN RAAGKSDDVA  60
   61 DALDYAQVSQ AVLEHIEQGR FLLVERVAEE VAELIMTRFA VPWLRIRLTK PGAVPQAKGV 120
  121 GVIIERARG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.39794
Match:	1nbuA
Description:	7,8-Dihydroneopterin Aldolase Complexed with Product From Mycobacterium Tuberculosis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
GTP cyclohydrolase I activity	4.32142445441644	bayes_pls_golite062009
cyclohydrolase activity	4.12134839958676	bayes_pls_golite062009
GTP cyclohydrolase activity	3.76376266092452	bayes_pls_golite062009
catalytic activity	2.57832156213163	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2.13367928146634	bayes_pls_golite062009
dihydroneopterin aldolase activity	2.05627605013559	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1.46072575729571	bayes_pls_golite062009
6-pyruvoyltetrahydropterin synthase activity	0.11818000438771	bayes_pls_golite062009
lyase activity	0.0597333135477298	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: