YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|46488407, gi|...
Organism: Plasmodium vivax
Length: 450 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|46488407, gi|....

Description E-value Query
Range
Subject
Range
gi|3095038 - gi|3095038|gb|AAC15794.1| plasmepsin [Plasmodium malariae]
350.0 [0..1] [450..1]
gi|3095036 - gi|3095036|gb|AAC15793.1| plasmepsin [Plasmodium ovale]
350.0 [0..1] [450..1]
gi|118344558, gi... - gi|55771082|dbj|BAD69801.1| cathepsin D1 [Takifugu rubripes], gi|118344558|ref|NP_001072052.1| cathe...
337.0 [0..62] [449..3]
gi|16507116 - gi|16507116|gb|AAL24045.1|AF427013_1 aspartic proteinase [Plasmodium chabaudi chabaudi]
337.0 [0..1] [450..1]
gi|114637864 - gi|114637864|ref|XP_001144824.1| PREDICTED: pepsinogen 5, group I (pepsinogen A) isoform 2 [Pan trog...
336.0 [0..71] [448..75]
gi|22651403 - gi|22651403|gb|AAL61540.1| cathepsin D precursor [Danio rerio]
336.0 [0..50] [450..1]

Back

Predicted Domain #1
Region A:
Residues: [1-75]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIAVKEQDY SNGLIKNSAA FENLKFSNIK NFKVQKRFQI LYYILFVFVT GIFFFFLIST  60
   61 YFFTPNYKVN KIVQN

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.11
Match: 2bjuA
Description: Plasmepsin II complexed with a highly active achiral inhibitor
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [76-450]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TEHLTLAFKI ERPYDKVLKT ISKKNLKNYI KETFNFFKSG YMKQNYLGSE NDVIELDDVA  60
   61 NIMFYGEGEV GDNHQKFMLI FDTGSANLWV PSKKCNSSGC SIKNLYDSSK SKSYEKDGTK 120
  121 VDITYGSGTV KGFFSKDLVT LGHLSMPYKF IEVTDTDDLE PIYSSVEFDG ILGLGWKDLS 180
  181 IGSIDPIVVE LKNQNKIDNA LFTFYLPVHD VHAGYLTIGG IEEKFYEGNI TYEKLNHDLY 240
  241 WQIDLDVHFG KQTMEKANVI VDSGTTTITA PSEFLNKFFA NLNVIKVPFL PFYVTTCDNK 300
  301 EMPTLEFKSA NNTYTLEPEY YMNPILEVDD TLCMITMLPV DIDSNTFILG DPFMRKYFTV 360
  361 FDYDKESVGF AIAKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.0
Match: 1miqA
Description: Plasmepsin (a hemoglobin-degrading enzyme)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
aspartic-type endopeptidase activity 7.9145950161796 bayes_pls_golite062009
aspartic-type peptidase activity 7.9145950161796 bayes_pls_golite062009
peptidase activity 5.78181196721293 bayes_pls_golite062009
endopeptidase activity 5.4888481808613 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 5.39972232367526 bayes_pls_golite062009
hydrolase activity 4.34796304893506 bayes_pls_golite062009
catalytic activity 1.54514410489082 bayes_pls_golite062009
binding 1.10054369202721 bayes_pls_golite062009
receptor binding 0.561225023505917 bayes_pls_golite062009
protein binding 0.193907750061394 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle