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View Structure Prediction Details

Protein: 4CL2_ARATH
Organism: Arabidopsis thaliana
Length: 556 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for 4CL2_ARATH.

Description E-value Query
Range
Subject
Range
4CL2_ARATH - 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2) (At4Cl2) (4-coumaroyl-CoA synthase 2) - Arabidopsis ...
549.0 [0..1] [556..1]

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Predicted Domain #1
Region A:
Residues: [1-556]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTQDVIVND QNDQKQCSND VIFRSRLPDI YIPNHLPLHD YIFENISEFA AKPCLINGPT  60
   61 GEVYTYADVH VTSRKLAAGL HNLGVKQHDV VMILLPNSPE VVLTFLAASF IGAITTSANP 120
  121 FFTPAEISKQ AKASAAKLIV TQSRYVDKIK NLQNDGVLIV TTDSDAIPEN CLRFSELTQS 180
  181 EEPRVDSIPE KISPEDVVAL PFSSGTTGLP KGVMLTHKGL VTSVAQQVDG ENPNLYFNRD 240
  241 DVILCVLPMF HIYALNSIML CSLRVGATIL IMPKFEITLL LEQIQRCKVT VAMVVPPIVL 300
  301 AIAKSPETEK YDLSSVRMVK SGAAPLGKEL EDAISAKFPN AKLGQGYGMT EAGPVLAMSL 360
  361 GFAKEPFPVK SGACGTVVRN AEMKILDPDT GDSLPRNKPG EICIRGNQIM KGYLNDPLAT 420
  421 ASTIDKDGWL HTGDVGFIDD DDELFIVDRL KELIKYKGFQ VAPAELESLL IGHPEINDVA 480
  481 VVAMKEEDAG EVPVAFVVRS KDSNISEDEI KQFVSKQVVF YKRINKVFFT DSIPKAPSGK 540
  541 ILRKDLRARL ANGLMN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 111.0
Match: 1ba3A
Description: FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-sulfur bonds 5.10123876514454 bayes_pls_golite062009
fatty acid ligase activity 4.83067429373059 bayes_pls_golite062009
long-chain fatty acid-CoA ligase activity 4.72692389032116 bayes_pls_golite062009
acetate-CoA ligase activity 4.48129067128523 bayes_pls_golite062009
acid-thiol ligase activity 4.28278725989432 bayes_pls_golite062009
CoA-ligase activity 4.12850865352867 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) 2.74744781333102 bayes_pls_golite062009
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity 2.74744781333102 bayes_pls_golite062009
luciferin monooxygenase activity 2.67396462766343 bayes_pls_golite062009
ligase activity 2.49556073715112 bayes_pls_golite062009
transcription regulator activity 2.31193176808353 bayes_pls_golite062009
catalytic activity 1.83545185797733 bayes_pls_golite062009
binding 1.5312519256537 bayes_pls_golite062009
transcription repressor activity 1.2638869228049 bayes_pls_golite062009
transferase activity, transferring acyl groups 0.464663038956639 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle