YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30264298, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	491 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30264298, gi|....

Description	E-value	Query Range	Subject Range
GCSPB_BACC1 - Probable glycine dehydrogenase (decarboxylating) subunit 2 OS=Bacillus cereus (strain ATCC 10987 / N...	8.0E-96	[1..491]	[1..491]
GCSPB_BACCN - Probable glycine dehydrogenase (decarboxylating) subunit 2 OS=Bacillus cytotoxicus (strain DSM 22905...	2.0E-95	[1..491]	[1..491]
gi\|242232502, gi... - gi\|242256019\|ref\|ZP_04800917.1\| Glycine dehydrogenase (decarboxylating) [Thermoanaerobacter sp. X513... gi\|167038898, gi... - gi\|167038898\|ref\|YP_001661883.1\| glycine dehydrogenase subunit 2 [Thermoanaerobacter sp. X514], gi\|1...	7.0E-95	[8..485]	[7..484]
gi\|241885035, gi... - gi\|241902573\|ref\|ZP_04787306.1\| Glycine dehydrogenase (decarboxylating) [Thermoanaerobacter brockii ... gi\|76589258, gi\|... - gi\|76795450\|ref\|ZP_00777823.1\| Glycine dehydrogenase (decarboxylating) [Thermoanaerobacter ethanolic...	2.0E-94	[8..485]	[7..484]
GCSPB_BACWK - Probable glycine dehydrogenase (decarboxylating) subunit 2 OS=Bacillus weihenstephanensis (strain KB...	2.0E-94	[1..491]	[1..491]
GCSPB_BACCR - Probable glycine dehydrogenase (decarboxylating) subunit 2 OS=Bacillus cereus (strain ATCC 14579 / D...	2.0E-92	[1..478]	[1..478]
GCSPB_BACHD, GCS... - Probable glycine dehydrogenase [decarboxylating] subunit 2 OS=Bacillus halodurans GN=gcvPB PE=3 SV=1... GCSPB_BACHD - Probable glycine dehydrogenase (decarboxylating) subunit 2 OS=Bacillus halodurans (strain ATCC BAA-1...	3.0E-92	[1..485]	[1..485]
gi\|221319625 - gi\|221319625\|ref\|ZP_03600919.1\| glycine dehydrogenase subunit 2 [Bacillus subtilis subsp. subtilis s... GCSB_BACSU, GCSP... - Probable glycine dehydrogenase [decarboxylating] subunit 2 OS=Bacillus subtilis GN=gcvPB PE=3 SV=1, ... gi\|221323901 - gi\|221323901\|ref\|ZP_03605195.1\| glycine dehydrogenase subunit 2 [Bacillus subtilis subsp. subtilis s... GCSPB_BACSU - Probable glycine dehydrogenase (decarboxylating) subunit 2 OS=Bacillus subtilis (strain 168) GN=gcvP... gi\|221314702 - gi\|221314702\|ref\|ZP_03596507.1\| glycine dehydrogenase subunit 2 [Bacillus subtilis subsp. subtilis s...	8.0E-92	[1..485]	[1..485]
gi\|77996273, gi\|... - gi\|78044158\|ref\|YP_359350.1\| glycine dehydrogenase subunit 2 [Carboxydothermus hydrogenoformans Z-29...	2.0E-91	[7..485]	[5..482]
gi\|223489247, gi... - gi\|254478938\|ref\|ZP_05092299.1\| glycine dehydrogenase (decarboxylating) [Carboxydibrachium pacificum... GCSB_THETN, GCSP... - Probable glycine dehydrogenase [decarboxylating] subunit 2 OS=Thermoanaerobacter tengcongensis GN=gc... GCSPB_CALS4 - Probable glycine dehydrogenase (decarboxylating) subunit 2 OS=Caldanaerobacter subterraneus subsp. t...	4.0E-91	[1..485]	[1..485]

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Predicted Domain #1

Region A:
Residues: [1-491]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNQDQALIF EVSKEGRIGY SLPKLDVEEV KLEDVFESDY IRVEDAELPE VSELDIMRHY  60
   61 TALSNRNHGV DSGFYPLGSC TMKYNPKINE SVARFAGFAN IHPLQDEKTV QGAMELMYDL 120
  121 QEHLIEITGM DTVTLQPAAG AHGEWTGLML IRAYHEANGD FNRTKVIVPD SAHGTNPASA 180
  181 TVAGFETITV KSNEHGLVDL EDLKRVVNEE TAALMLTNPN TLGLFEENIL EMAEIVHNAG 240
  241 GKLYYDGANL NAVLSQARPG DMGFDVVHLN LHKTFTGPHG GGGPGSGPVG VKADLIPYLP 300
  301 KPILEKTENG YHFNYDRPEA IGRVKPFYGN FGINVRAYTY IRSMGPDGLR AVTEYAVLNA 360
  361 NYMMRRLAPF YDLPFDRHCK HEFVLSGRRQ KKLGVRTLDI AKRLLDFGYH PPTIYFPLNV 420
  421 EECIMIEPTE TESKETLDGF IDKMIQIAKE VEENPEVVQE APHTTVIKRL DETMAARKPV 480
  481 LRYAKPAPVQ V

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	72.09691
Match:	1wytB
Description:	Crystal structure of glycine decarboxylase (P-protein) of the glycine cleavage system, in apo form
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.66922865456094	bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity	2.10290066978837	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	2.10290066978837	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.85532625717753	bayes_pls_golite062009
transaminase activity	1.83482013760414	bayes_pls_golite062009
transferase activity	0.93810038069762	bayes_pls_golite062009
glycine hydroxymethyltransferase activity	0.71980637947887	bayes_pls_golite062009
methyltransferase activity	0.58373273750311	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.51745245786841	bayes_pls_golite062009
O-phospho-L-serine:2-oxoglutarate aminotransferase activity	0.38671377495281	bayes_pls_golite062009
lyase activity	0.0414385380659299	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: