YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30264473, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	423 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30264473, gi|....

Description	E-value	Query Range	Subject Range
SYH_BACCN - Histidine--tRNA ligase OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)...	3.0E-82	[1..423]	[1..423]
SYH_BACHD - Histidine--tRNA ligase OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 915... SYH_BACHD - Histidyl-tRNA synthetase OS=Bacillus halodurans GN=hisS PE=3 SV=1	9.0E-82	[1..422]	[1..422]
SYH1_BACSK - Histidine--tRNA ligase 1 OS=Bacillus clausii (strain KSM-K16) GN=hisS1 PE=3 SV=1	1.0E-81	[1..422]	[1..422]
SYH2_BACCR - Histidine--tRNA ligase 2 OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NC... gi\|229152607, gi... - gi\|229152607\|ref\|ZP_04280796.1\| Histidyl-tRNA synthetase 2 [Bacillus cereus m1550], gi\|228630868\|gb\|... gi\|218161610, gi... - gi\|218233653\|ref\|YP_002369213.1\| histidyl-tRNA synthetase [Bacillus cereus B4264], gi\|218161610\|gb\|A... gi\|228653801, gi... - gi\|229129684\|ref\|ZP_04258652.1\| Histidyl-tRNA synthetase 2 [Bacillus cereus BDRD-Cer4], gi\|228653801... gi\|228636472, gi... - gi\|229146975\|ref\|ZP_04275337.1\| Histidyl-tRNA synthetase 2 [Bacillus cereus BDRD-ST24], gi\|228636472... gi\|229048113, gi... - gi\|229048113\|ref\|ZP_04193684.1\| Histidyl-tRNA synthetase 2 [Bacillus cereus AH676], gi\|228723216\|gb\|... gi\|228671632, gi... - gi\|229111876\|ref\|ZP_04241422.1\| Histidyl-tRNA synthetase 2 [Bacillus cereus Rock1-15], gi\|228671632\|...	2.0E-81	[1..423]	[1..423]
gi\|47566592, gi\|... - gi\|47566592\|ref\|ZP_00237414.1\| histidyl-tRNA synthetase [Bacillus cereus G9241], gi\|47556622\|gb\|EAL1...	2.0E-81	[1..423]	[1..423]
gi\|167636503, gi... - gi\|167636503\|ref\|ZP_02394800.1\| histidyl-tRNA synthetase [Bacillus anthracis str. A0442], gi\|1675280... gi\|65321770 - gi\|65321770\|ref\|ZP_00394729.1\| COG0124: Histidyl-tRNA synthetase [Bacillus anthracis str. A2012] gi\|190561882, gi... - gi\|190566891\|ref\|ZP_03019807.1\| histidyl-tRNA synthetase [Bacillus anthracis Tsiankovskii-I], gi\|190... gi\|227006448, gi... - gi\|227817182\|ref\|YP_002817191.1\| histidyl-tRNA synthetase [Bacillus anthracis str. CDC 684], gi\|2270... gi\|195993010, gi... - gi\|196034468\|ref\|ZP_03101877.1\| histidyl-tRNA synthetase [Bacillus cereus W], gi\|195993010\|gb\|EDX569... gi\|170688654, gi... - gi\|170688654\|ref\|ZP_02879859.1\| histidyl-tRNA synthetase [Bacillus anthracis str. A0465], gi\|1706673... gi\|228935724, gi... - gi\|228935724\|ref\|ZP_04098537.1\| Histidyl-tRNA synthetase 2 [Bacillus thuringiensis serovar andalousi... gi\|172081027, gi... - gi\|177653972\|ref\|ZP_02936013.1\| histidyl-tRNA synthetase [Bacillus anthracis str. A0174], gi\|1720810... gi\|228929448, gi... - gi\|228929448\|ref\|ZP_04092469.1\| Histidyl-tRNA synthetase 2 [Bacillus thuringiensis serovar pondicher... gi\|228689945, gi... - gi\|229093474\|ref\|ZP_04224577.1\| Histidyl-tRNA synthetase 2 [Bacillus cereus Rock3-42], gi\|228689945\|... gi\|228811475, gi... - gi\|228948117\|ref\|ZP_04110401.1\| Histidyl-tRNA synthetase 2 [Bacillus thuringiensis serovar monterrey... gi\|229604899, gi... - gi\|229604899\|ref\|YP_002868690.1\| histidine--tRNA ligase [Bacillus anthracis str. A0248], gi\|22926930... gi\|228659246, gi... - gi\|229123944\|ref\|ZP_04253136.1\| Histidyl-tRNA synthetase 2 [Bacillus cereus 95/8201], gi\|228659246\|g... gi\|254736506 - gi\|254736506\|ref\|ZP_05194212.1\| histidyl-tRNA synthetase [Bacillus anthracis str. Western North Amer... gi\|254684159 - gi\|254684159\|ref\|ZP_05148019.1\| histidyl-tRNA synthetase [Bacillus anthracis str. CNEVA-9066] gi\|254751357 - gi\|254751357\|ref\|ZP_05203394.1\| histidyl-tRNA synthetase [Bacillus anthracis str. Vollum] gi\|254741544 - gi\|254741544\|ref\|ZP_05199231.1\| histidyl-tRNA synthetase [Bacillus anthracis str. Kruger B] gi\|254757689 - gi\|254757689\|ref\|ZP_05209716.1\| histidyl-tRNA synthetase [Bacillus anthracis str. Australia 94]	3.0E-81	[1..423]	[54..476]
gi\|217961893, gi... - gi\|217961893\|ref\|YP_002340463.1\| histidyl-tRNA synthetase [Bacillus cereus AH187], gi\|217063931\|gb\|A... gi\|206975990, gi... - gi\|206975990\|ref\|ZP_03236900.1\| histidyl-tRNA synthetase [Bacillus cereus H3081.97], gi\|206745742\|gb... gi\|222097847, gi... - gi\|222097847\|ref\|YP_002531904.1\| histidyl-tRNA synthetase [Bacillus cereus Q1], gi\|221241905\|gb\|ACM1... SYH2_BACC1 - Histidine--tRNA ligase 2 OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=hisS2 PE=3 SV=1	3.0E-81	[1..423]	[1..423]
gi\|163942153, gi... - gi\|89209366\|ref\|ZP_01187795.1\| Histidyl-tRNA synthetase, class IIa [Bacillus weihenstephanensis KBAB...	4.0E-81	[1..423]	[1..423]
SYH_GEOKA - Histidine--tRNA ligase OS=Geobacillus kaustophilus (strain HTA426) GN=hisS PE=3 SV=1 SYH_GEOKA - Histidyl-tRNA synthetase OS=Geobacillus kaustophilus GN=hisS PE=3 SV=1	6.0E-81	[1..422]	[1..422]
gi\|89084502, gi\|... - gi\|89100799\|ref\|ZP_01173652.1\| histidyl-tRNA synthetase [Bacillus sp. NRRL B-14911], gi\|89084502\|gb\|...	3.0E-80	[1..422]	[1..422]

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Predicted Domain #1

Region A:
Residues: [1-423]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIQIPRGTQ DILPGTVELW QYIEGQAREI CRRYNYKEIR TPIFEHTELF LRGVGDTTDI  60
   61 VQKEMYSFQD RGERSLTLRP EGTAPVVRSY VENKMFGDAT QPTKLYYIGQ MFRYERPQAG 120
  121 RYRQFVQFGI EAIGSNDPAI DAEVIALAVE FYRGMGLKNI KVVLNSLGDA ASRQAHRDAL 180
  181 IAHFEPRIGE FCSDCQSRLE KNPLRILDCK KDRNHELMGT APSITEYLNE DSAVYYDKVQ 240
  241 ELLTMMDVPF EKDPNLVRGL DYYQHTVFEI MSEAEGFGAI TTLSGGGRYN GLVQEIGGPE 300
  301 MPGIGFAMSI ERLIMALKAE NIELPIEHSI DCYVVALGEK AKDHAAKVAF DLRKAGLAVE 360
  361 KDYLDRKMKA QFKSADRLKA KFVAVLGEDE LDKGIINLKD MATGEQEEVA LDVFASYVAE 420
  421 KLI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	73.0
Match:	1qe0A
Description:	Histidyl-tRNA synthetase (HisRS), C-terminal domain; Histidyl-tRNA synthetase (HisRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming aminoacyl-tRNA and related compounds	7.89468709683036	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	7.89468709683036	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.88410036819636	bayes_pls_golite062009
ligase activity	6.92073480193262	bayes_pls_golite062009
histidine-tRNA ligase activity	5.91343220471745	bayes_pls_golite062009
phenylalanine-tRNA ligase activity	2.99105702052936	bayes_pls_golite062009
serine-tRNA ligase activity	2.46505535069103	bayes_pls_golite062009
glycine-tRNA ligase activity	2.29229136935761	bayes_pls_golite062009
threonine-tRNA ligase activity	2.18642354927	bayes_pls_golite062009
catalytic activity	1.99372273395202	bayes_pls_golite062009
alanine-tRNA ligase activity	1.82594054955281	bayes_pls_golite062009
lysine-tRNA ligase activity	1.72324031407565	bayes_pls_golite062009
asparagine-tRNA ligase activity	0.921492123574877	bayes_pls_golite062009
binding	0.916222310895772	bayes_pls_golite062009
transcription regulator activity	0.375542987753806	bayes_pls_golite062009
nucleic acid binding	0.281662799812287	bayes_pls_golite062009
DNA binding	0.0309732052586011	bayes_pls_golite062009
aspartate-tRNA ligase activity	0.00572514744734753	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: