YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30259321, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	645 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30259321, gi|....

Description	E-value	Query Range	Subject Range
gi\|221315161 - gi\|221315161\|ref\|ZP_03596966.1\| threonyl-tRNA synthetase [Bacillus subtilis subsp. subtilis str. NCI... SYT1_BACSU - Threonine--tRNA ligase 1 OS=Bacillus subtilis (strain 168) GN=thrS PE=2 SV=1 gi\|221324361 - gi\|221324361\|ref\|ZP_03605655.1\| threonyl-tRNA synthetase [Bacillus subtilis subsp. subtilis str. SMY... SYT1_BACSU - Threonine--tRNA ligase 1 OS=Bacillus subtilis GN=thrS PE=2 SV=1	0.0	[1..645]	[1..643]
SYT_BACHD - Threonine--tRNA ligase OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 915... SYT_BACHD - Threonyl-tRNA synthetase OS=Bacillus halodurans GN=thrS PE=3 SV=1	0.0	[1..645]	[1..645]
SYT_BURS3 - Threonine--tRNA ligase OS=Burkholderia sp. (strain 383) GN=thrS PE=3 SV=1 SYT_BURL3 - Threonine--tRNA ligase OS=Burkholderia lata (strain ATCC 17760 / LMG 22485 / NCIMB 9086 / R18194 / 3...	0.0	[4..644]	[1..632]
gi\|94310105, gi\|... - gi\|94310105\|ref\|YP_583315.1\| threonyl-tRNA synthetase [Ralstonia metallidurans CH34], gi\|93353957\|gb...	0.0	[4..643]	[29..659]
SYT_BURVG - Threonine--tRNA ligase OS=Burkholderia vietnamiensis (strain G4 / LMG 22486) GN=thrS PE=3 SV=1	0.0	[4..644]	[1..632]
SYT_METFK - Threonine--tRNA ligase OS=Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875) GN=thrS PE...	0.0	[4..644]	[1..632]
gi\|254245609, gi... - gi\|254245609\|ref\|ZP_04938930.1\| Threonyl-tRNA synthetase, class IIa [Burkholderia cenocepacia PC184]... gi\|162218055, gi... - gi\|67656296\|ref\|ZP_00453679.1\| Threonyl-tRNA synthetase, class IIa [Burkholderia cenocepacia AU 1054... gi\|162227933, gi... - gi\|67668173\|ref\|ZP_00465361.1\| Threonyl-tRNA synthetase, class IIa [Burkholderia cenocepacia HI2424]...	0.0	[4..644]	[1..632]
gi\|228960844, gi... - gi\|228960844\|ref\|ZP_04122479.1\| Threonyl-tRNA synthetase [Bacillus thuringiensis serovar pakistani s... gi\|228804833, gi... - gi\|228954844\|ref\|ZP_04116864.1\| Threonyl-tRNA synthetase [Bacillus thuringiensis serovar kurstaki st... gi\|228923319, gi... - gi\|228923319\|ref\|ZP_04086607.1\| Threonyl-tRNA synthetase [Bacillus thuringiensis serovar huazhongens... gi\|229112040, gi... - gi\|229112040\|ref\|ZP_04241583.1\| Threonyl-tRNA synthetase [Bacillus cereus Rock1-15], gi\|228671363\|gb... gi\|228701416, gi... - gi\|229081828\|ref\|ZP_04214320.1\| Threonyl-tRNA synthetase [Bacillus cereus Rock4-2], gi\|228701416\|gb\|... gi\|228711011, gi... - gi\|229072077\|ref\|ZP_04205286.1\| Threonyl-tRNA synthetase [Bacillus cereus F65185], gi\|228711011\|gb\|E... gi\|229048283, gi... - gi\|229048283\|ref\|ZP_04193851.1\| Threonyl-tRNA synthetase [Bacillus cereus AH676], gi\|228723008\|gb\|EE... gi\|228602451, gi... - gi\|229180894\|ref\|ZP_04308229.1\| Threonyl-tRNA synthetase [Bacillus cereus 172560W], gi\|228602451\|gb\|... gi\|229152770, gi... - gi\|229152770\|ref\|ZP_04280953.1\| Threonyl-tRNA synthetase [Bacillus cereus m1550], gi\|228630590\|gb\|EE... gi\|218234238, gi... - gi\|218234238\|ref\|YP_002369371.1\| threonyl-tRNA synthetase [Bacillus cereus B4264], gi\|218162195\|gb\|A... gi\|229147134, gi... - gi\|229147134\|ref\|ZP_04275493.1\| Threonyl-tRNA synthetase [Bacillus cereus BDRD-ST24], gi\|228636383\|g... gi\|206969938, gi... - gi\|206969938\|ref\|ZP_03230892.1\| threonyl-tRNA synthetase [Bacillus cereus AH1134], gi\|206735626\|gb\|E... gi\|229129859, gi... - gi\|229129859\|ref\|ZP_04258825.1\| Threonyl-tRNA synthetase [Bacillus cereus BDRD-Cer4], gi\|228653550\|g... gi\|229198724, gi... - gi\|229198724\|ref\|ZP_04325422.1\| Threonyl-tRNA synthetase [Bacillus cereus m1293], gi\|228584746\|gb\|EE... gi\|228590615, gi... - gi\|229192776\|ref\|ZP_04319734.1\| Threonyl-tRNA synthetase [Bacillus cereus ATCC 10876], gi\|228590615\|... gi\|42739683, gi\|... - gi\|42783753\|ref\|NP_981000.1\| threonyl-tRNA synthetase [Bacillus cereus ATCC 10987], gi\|42739683\|gb\|A...	0.0	[1..645]	[1..645]
SYT_POLSQ - Threonine--tRNA ligase OS=Polynucleobacter necessarius subsp. asymbioticus (strain DSM 18221 / CIP 1...	0.0	[4..645]	[1..633]
SYT_CUPPJ - Threonine--tRNA ligase OS=Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) GN=thrS PE=3 SV=1	0.0	[4..643]	[1..631]

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Predicted Domain #1

Region A:
Residues: [1-645]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADVVKITFP DGAVKEFPKG VTTEEIAASI SPGLKKKAVA GKLNDEMIDL VTPIEEDGAV  60
   61 SIITLDSEDG LYILRHSTAH LLAQALKRLY KDVKVELGIG PVIENGFYYD IDMEEAITVE 120
  121 DFKKIEKEMQ KIVNENLEIV RHEVPRAEAI RRFEEIGDEL KLDLINDLPE DAVISIYEQG 180
  181 EFFDLCRGVH LPSTGKIKVF KLLSVAGAYW RGDSNNKMLQ RIYGTAFVKK AELDEHLRML 240
  241 EEAKERDHRK LGKELKLFTN SQKVGQGLPL WLPKGATIRR IIERYIVDKE ASLGYDHVYT 300
  301 PVLGSRELYE TSGHWNHYRD GMFPSMEMDN EELVLRPMNC PHHMMVYKND IHSYRELPIR 360
  361 IAELGTMHRY EMSGALSGLQ RVRGMTLNDA HIFVRPDQIK EELKRVVNLT LEVYKDFGLE 420
  421 NYSFRLSYRD PEDTKKYYAD DEMWEKAQGM LKEAMDEMGL DYYEAEGEAA FYGPKLDVQV 480
  481 RTALGKDETL STVQLDFLLP ERFELSYVGE DGKQHRPVVI HRGVVSTMER FVAFLIEEYK 540
  541 GAFPTWLAPV QVQVIPVSPQ VHLDYAKKVQ DELRRAGIRV ELDTREEKIG YKIREAQMQK 600
  601 IPYMLVVGDN EVTENGVNVR KYGEQKSETI ALDAFVDMIK VEGKR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	116.0
Match:	1nyqA
Description:	Structure of Staphylococcus aureus threonyl-tRNA synthetase complexed with an analogue of threonyl adenylate
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming aminoacyl-tRNA and related compounds	7.89468709683036	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	7.89468709683036	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.88410036819636	bayes_pls_golite062009
ligase activity	6.92073480193262	bayes_pls_golite062009
threonine-tRNA ligase activity	6.47381405106149	bayes_pls_golite062009
proline-tRNA ligase activity	3.75014065504119	bayes_pls_golite062009
phenylalanine-tRNA ligase activity	2.99105702052936	bayes_pls_golite062009
serine-tRNA ligase activity	2.46505535069103	bayes_pls_golite062009
glycine-tRNA ligase activity	2.29229136935761	bayes_pls_golite062009
catalytic activity	1.99372273395202	bayes_pls_golite062009
alanine-tRNA ligase activity	1.82594054955281	bayes_pls_golite062009
lysine-tRNA ligase activity	1.72324031407565	bayes_pls_golite062009
histidine-tRNA ligase activity	1.72215103383322	bayes_pls_golite062009
binding	1.11470390774037	bayes_pls_golite062009
transcription regulator activity	1.0753492604686	bayes_pls_golite062009
asparagine-tRNA ligase activity	0.921492123574877	bayes_pls_golite062009
nucleic acid binding	0.897558352141977	bayes_pls_golite062009
DNA binding	0.854148126675211	bayes_pls_golite062009
transcription repressor activity	0.55217603492525	bayes_pls_golite062009
transcription factor activity	0.283508546234551	bayes_pls_golite062009
aspartate-tRNA ligase activity	0.00572514744734753	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: