YRC Public Data Repository - Protein Structure Prediction

Protein:	TRPC_XYLFA
Organism:	Xylella fastidiosa 9a5c
Length:	264 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRPC_XYLFA.

Description	E-value	Query Range	Subject Range
gi\|66044011, gi\|... - gi\|66044011\|ref\|YP_233852.1\| indole-3-glycerol-phosphate synthase [Pseudomonas syringae pv. syringae...	263.0	[0..1]	[264..1]
gi\|94427889, gi\|... - gi\|94500031\|ref\|ZP_01306566.1\| indole-3-glycerol-phosphate synthase [Oceanobacter sp. RED65], gi\|944...	256.0	[0..2]	[262..4]
gi\|48861005, gi\|... - gi\|90020401\|ref\|YP_526228.1\| indole-3-glycerol phosphate synthase [Saccharophagus degradans 2-40], g...	256.0	[0..2]	[262..5]
gi\|83648766, gi\|... - gi\|83648766\|ref\|YP_437201.1\| indole-3-glycerol phosphate synthase [Hahella chejuensis KCTC 2396], gi...	255.0	[0..2]	[261..5]
gi\|114327483, gi... - gi\|114327483\|ref\|YP_744640.1\| indole-3-glycerol-phosphate synthase [Granulibacter bethesdensis CGDNI...	254.0	[0..3]	[262..35]
TRPC_XYLFT - Indole-3-glycerol phosphate synthase OS=Xylella fastidiosa (strain Temecula1 / ATCC 700964) GN=trpC ... TRPC_XYLF2 - Indole-3-glycerol phosphate synthase OS=Xylella fastidiosa (strain M23) GN=trpC PE=3 SV=1 gi\|71900807, gi\|... - gi\|71900807\|ref\|ZP_00682926.1\| Indole-3-glycerol-phosphate synthase [Xylella fastidiosa Ann-1], gi\|7...	253.0	[0..1]	[264..1]
gi\|71276381, gi\|... - gi\|71276381\|ref\|ZP_00652658.1\| Indole-3-glycerol-phosphate synthase [Xylella fastidiosa Dixon], gi\|7... gi\|71898636, gi\|... - gi\|71898636\|ref\|ZP_00680806.1\| Indole-3-glycerol-phosphate synthase [Xylella fastidiosa Ann-1], gi\|7...	253.0	[0..1]	[264..1]
gi\|25291422 - gi\|25291422\|pir\|\|AE3357 indole-3-glycerol phosphate synthase (EC 4.1.1.48) [imported] - Brucella mel... gi\|237815563, gi... - gi\|237815563\|ref\|ZP_04594560.1\| Indole-3-glycerol phosphate synthase [Brucella abortus str. 2308 A],... gi\|17987126, gi\|... - gi\|17987126\|ref\|NP_539760.1\| indole-3-glycerol-phosphate synthase [Brucella melitensis 16M], gi\|1798...	251.0	[0..1]	[263..36]
gi\|23105977, gi\|... - gi\|67155296\|ref\|ZP_00416924.1\| Indole-3-glycerol-phosphate synthase [Azotobacter vinelandii AvOP], r... TRPC_AZOVD - Indole-3-glycerol phosphate synthase OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=trpC P...	250.0	[0..1]	[262..3]
gi\|58583783, gi\|... - gi\|58583783\|ref\|YP_202799.1\| indole-3-glycerol-phosphate synthase [Xanthomonas oryzae pv. oryzae KAC...	250.0	[0..1]	[263..80]

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Predicted Domain #1

Region A:
Residues: [1-264]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNILTKIIA WKVEEIAERL LHVSQAELVA RCADLPTPRG FAGALQATIA HGDPAVIAEI  60
   61 KKASPSKGVL REDFRPAEIA ISYELGGASC LSVLTDVHFF KGHDDYLSQA RDACTLPVLR 120
  121 KDFTIDPYQV YEARVLGADC ILLIVAALDD AQLVDLSGLA LQLGMDVLVE VHDIDELERA 180
  181 IQISAPLIGI NNRNLSTFNV SLETTLTMKG LVPRDRLLVS ESGILTSADV QRLRAAGVNA 240
  241 FLVGEAFMRA TEPGESLREM FFIT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	61.0
Match:	1piiA
Description:	THREE-DIMENSIONAL STRUCTURE OF THE BIFUNCTIONAL ENZYME PHOSPHORIBOSYLANTHRANILATE ISOMERASE: INDOLEGLYCEROLPHOSPHATE SYNTHASE FROM ESCHERICHIA COLI REFINED AT 2.0 ANGSTROMS RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
tryptophan synthase activity	3.15663465352598	bayes_pls_golite062009
indole-3-glycerol-phosphate synthase activity	3.12120866545322	bayes_pls_golite062009
catalytic activity	2.81275055404078	bayes_pls_golite062009
phosphoribosylanthranilate isomerase activity	2.655130814615	bayes_pls_golite062009
carbon-carbon lyase activity	2.44001937916931	bayes_pls_golite062009
carboxy-lyase activity	1.80978905789979	bayes_pls_golite062009
lyase activity	0.9228652996943	bayes_pls_golite062009
imidazoleglycerol-phosphate synthase activity	0.82314869965119	bayes_pls_golite062009
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity	0.302746738903759	bayes_pls_golite062009
isomerase activity	0.14149405165663	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: