YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7436631
Organism:	Helicobacter pylori
Length:	208 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7436631.

Description	E-value	Query Range	Subject Range
gi\|108563462, gi... - gi\|108563462\|ref\|YP_627778.1\| 2-keto-3-deoxy-6-phosphogluconate aldolase [Helicobacter pylori HPAG1]...	207.0	[0..1]	[208..1]
gi\|7436630 - pir\|\|D71859 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) - Helicobacter pylori (strain ... gi\|4155605, gi\|1... - gi\|4155605\|gb\|AAD06596.1\| 2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE ALDOLASE [Helicobacter pylori J99], gi\|1...	197.0	[0..1]	[208..1]
gi\|109714266, gi... - gi\|109947045\|ref\|YP_664273.1\| 2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate ...	195.0	[0..1]	[206..5]
gi\|113461739, gi... - gi\|23467619\|ref\|ZP_00123199.1\| COG0800: 2-keto-3-deoxy-6-phosphogluconate aldolase [Haemophilus somn...	192.0	[0..3]	[207..6]
gi\|170718550, gi... - gi\|53728725\|ref\|ZP_00131830.2\| COG0800: 2-keto-3-deoxy-6-phosphogluconate aldolase [Haemophilus somn...	191.0	[0..3]	[207..6]
gi\|54308469, gi\|... - gi\|54308469\|ref\|YP_129489.1\| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Ph...	189.0	[0..1]	[207..1]
gi\|32033966 - gi\|32033966\|ref\|ZP_00134222.1\| COG0800: 2-keto-3-deoxy-6-phosphogluconate aldolase [Actinobacillus p...	187.0	[0..3]	[207..7]
gi\|11268131 - pir\|\|B81088 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) - Neisseria meningitidis (stra... gi\|15794505, gi\|... - gi\|7380253\|emb\|CAB84839.1\| 2-keto-4-hydroxyglutarate aldolase [Neisseria meningitidis Z2491], gi\|218... gi\|15677255, gi\|... - gi\|7226633\|gb\|AAF41758.1\| 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldola...	187.0	[0..7]	[208..8]
gi\|240118073 - gi\|240118073\|ref\|ZP_04732135.1\| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase ... gi\|59801133, gi\|... - gi\|59801133\|ref\|YP_207845.1\| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Ne... gi\|240115778 - gi\|240115778\|ref\|ZP_04729840.1\| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase ... gi\|240113021 - gi\|240113021\|ref\|ZP_04727511.1\| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase ...	186.0	[0..7]	[208..8]
gi\|59714170, gi\|... - gi\|59714170\|ref\|YP_206945.1\| keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Vi...	186.0	[0..1]	[207..1]

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Predicted Domain #1

Region A:
Residues: [1-208]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQDKIIEVLQ ISPIVPVVVI ENIKDAVPLA QSLIEGGIPI IEVTLRSSCA LEAIELIAKN  60
   61 MPKMRVGAGT ILNPTQLEQA QNRGAEFLIS PGLTIKLLEH AKKKDMPLIP GVSSSSEVMQ 120
  121 ALELGYSALK FFPAEYCGGV KLLNAFNGPF KGVKFCPTGG ISADNMRSYL NLENVLCVGG 180
  181 SWLTPKNLIQ NKEWDKITEI CKRALALR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.69897
Match:	1vhcA
Description:	Crystal structure of a putative KHG/KDPG aldolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
2-dehydro-3-deoxy-phosphogluconate aldolase activity	3.5031381823147	bayes_pls_golite062009
catalytic activity	2.67031204377352	bayes_pls_golite062009
fructose-bisphosphate aldolase activity	0.840107349031025	bayes_pls_golite062009
lyase activity	0.740424046054758	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	0.643395146148785	bayes_pls_golite062009
transferase activity	0.464721888799972	bayes_pls_golite062009
aldehyde-lyase activity	0.351872954170322	bayes_pls_golite062009
transaldolase activity	0.337067552042715	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: