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View Structure Prediction Details

Protein: wrs-2
Organism: Caenorhabditis elegans
Length: 360 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for wrs-2.

Description E-value Query
Range
Subject
Range
gi|56685213, gi|... - gi|56750254|ref|YP_170955.1| tryptophanyl-tRNA synthetase [Synechococcus elongatus PCC 6301], gi|566...
gi|45512837 - ref|ZP_00164403.1| COG0180: Tryptophanyl-tRNA synthetase [Synechococcus elongatus PCC 7942]
353.0 [0..30] [359..3]

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Predicted Domain #1
Region A:
Residues: [1-360]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIFSGKFTSH LLNYGFKPNN LRLLSTSTHP TIYFTGIQPT GIPHLGNFFG SIEPWTELQN  60
   61 SVDKNILMML SVVDQHAISL GPLPANELRQ NTHQMTASLI ACGVDPNRTL LFRQSDVPQI 120
  121 AQISWILGSL QTTSKLARLP QYKEKKERFK KGDIPVGLLT YPLLQAADVL TFKATTVPVG 180
  181 EDQSQHLNLL GGLAYAFNKT YETEIFPIPK QLTRESHARI RSLREPEKKM SKSSGGPRSR 240
  241 IEITDSRSTI IEKCQKAQSD NAGKVTYDKE NRLAVSNLLD LYSAVTKTQT SEIDFSNWTT 300
  301 LDLKMNLAEA VDKRLAPIRQ KFEELQNTGE VDKVLTENGE KAREIAEKNL EEIRRTIGFL 360
  361 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.045757
Match: 1i6kA
Description: Tryptophanyl-tRNA synthetase (TrpRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-oxygen bonds 7.16276509815667 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 7.16276509815667 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 7.13957775963187 bayes_pls_golite062009
ligase activity 6.11211476973434 bayes_pls_golite062009
tryptophan-tRNA ligase activity 5.34430928486195 bayes_pls_golite062009
glutamate-tRNA ligase activity 2.63681738794687 bayes_pls_golite062009
methionine-tRNA ligase activity 2.56893064485672 bayes_pls_golite062009
catalytic activity 2.37674226834122 bayes_pls_golite062009
tyrosine-tRNA ligase activity 1.88984817882585 bayes_pls_golite062009
arginine-tRNA ligase activity 1.50161401062914 bayes_pls_golite062009
cysteine-tRNA ligase activity 0.844943947059557 bayes_pls_golite062009
binding 0.535704308663141 bayes_pls_golite062009
nucleic acid binding 0.449504767632354 bayes_pls_golite062009
nucleotidyltransferase activity 0.2293846471193 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.126511747475258 bayes_pls_golite062009
glutamine-tRNA ligase activity 0.118292082006187 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle