YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|33151354, gi\|...
Organism:	Haemophilus ducreyi 35000HP
Length:	233 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|33151354, gi|....

Description	E-value	Query Range	Subject Range
gi\|170718159, gi... - gi\|46156134\|ref\|ZP_00133340.2\| COG2932: Predicted transcriptional regulator [Haemophilus somnus 2336...	145.0	[0..1]	[233..1]
gi\|68544779, gi\|... - gi\|68544779\|ref\|ZP_00584383.1\| Helix-turn-helix motif:Peptidase S24, S26A and S26B [Shewanella balti...	138.0	[0..9]	[229..2]
gi\|160875134, gi... - gi\|160875134\|ref\|YP_001554450.1\| putative phage repressor [Shewanella baltica OS195], gi\|160860656\|g...	138.0	[0..9]	[229..2]
gi\|91716618, gi\|... - gi\|91794616\|ref\|YP_564267.1\| transciptional regulator [Shewanella denitrificans OS217], gi\|91716618\|...	131.0	[0..13]	[229..4]
gi\|117609813, gi... - gi\|69258750\|ref\|ZP_00607262.1\| Helix-turn-helix motif:Peptidase S24, S26A and S26B [Magnetococcus sp...	128.0	[0..10]	[232..32]
YE76_HAEIN, Y147... - (P44207) Putative HTH-type transcriptional regulator HI1476, Uncharacterized HTH-type transcriptiona... Y1476_HAEIN - Uncharacterized HTH-type transcriptional regulator HI_1476 OS=Haemophilus influenzae (strain ATCC 51...	127.0	[0..6]	[233..4]
gi\|254222472, gi... - gi\|75822998\|ref\|ZP_00752538.1\| COG2932: Predicted transcriptional regulator [Vibrio cholerae RC385],... gi\|229528221, gi... - gi\|229528221\|ref\|ZP_04417612.1\| hypothetical protein VCG_001301 [Vibrio cholerae 12129(1)], gi\|22933... tr\|D7HBR5\|D7HBR5... - Repressor protein CI OS=Vibrio cholerae GN=cI PE=4 SV=1, HTH-type transcriptional regulator PrtR OS=...	126.0	[0..7]	[229..2]
gi\|24374516, gi\|... - gi\|24374516\|ref\|NP_718559.1\| prophage LambdaSo, Cro/CI family transcriptional regulator [Shewanella ... SO2990 - prophage LambdaSo transcriptional regulator, Cro/CI family	122.0	[0..2]	[229..1]

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Predicted Domain #1

Region A:
Residues: [1-233]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIKFKNTSL IGNRIRDERE KAGRSRNELA DTLGLSLSTL QLWETNEREP QASMIITIAE  60
   61 ELGVSPSYLL TGETEEGEVK TPVAKTQPTQ QIQDISMINS FETISVSAGF GSFNEGVTEP 120
  121 DGQVPYDDEL LRKLGVKPRH CAVFWASGNS MQPTIDNGDQ LLVDLDRKDI KSDSVYLVQN 180
  181 GTSVWVKRVK VRWNSVELIS DNKEEYDPII LTTTDAENLQ VIGQVVHIGK ILI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	15.69897
Match:	1jhfA
Description:	LexA repressor, N-terminal DNA-binding domain; LexA C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.13370593570418	bayes_pls_golite062009
nucleic acid binding	1.55694924162006	bayes_pls_golite062009
DNA binding	1.42504441648262	bayes_pls_golite062009
binding	1.26570271545147	bayes_pls_golite062009
transcription factor activity	0.911559854968835	bayes_pls_golite062009
protein binding	0.378066881516827	bayes_pls_golite062009
catalytic activity	0.0451617952658021	bayes_pls_golite062009
transcription repressor activity	0.0123300332408647	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: