YRC Public Data Repository - Protein Structure Prediction

Protein:	TET_PYRHO
Organism:	Pyrococcus horikoshii OT3
Length:	353 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TET_PYRHO.

Description	E-value	Query Range	Subject Range
gi\|55670846, gi\|... - gi\|55670848\|pdb\|1XFO\|D Chain D, Crystal Structure Of An Archaeal Aminopeptidase, gi\|55670847\|pdb\|1XF...	263.0	[0..1]	[353..5]
gi\|14520851, gi\|... - gi\|5458068\|emb\|CAB49557.1\| endO 1,4-betaglucanase (cellulase M) (EGM) [Pyrococcus abyssi GE5], gi\|14... gi\|7435584, gi\|5... - pir\|\|D75105 aminopeptidase m42 PAB0437 [imported] - Pyrococcus abyssi (strain Orsay), gi\|5458068\|em...	262.0	[0..10]	[353..5]
gi\|57640716, gi\|... - gi\|57640716\|ref\|YP_183194.1\| deblocking aminopeptidase [Thermococcus kodakarensis KOD1], gi\|57159040...	261.0	[0..10]	[353..5]
gi\|18893685, gi\|... - gi\|18977919\|ref\|NP_579276.1\| endoglucanase [Pyrococcus furiosus DSM 3638], gi\|18893685\|gb\|AAL81671.1...	260.0	[0..10]	[353..5]
DAPE_IDILO - Succinyl-diaminopimelate desuccinylase OS=Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L... DAPE_IDILO - Succinyl-diaminopimelate desuccinylase OS=Idiomarina loihiensis GN=dapE PE=3 SV=1	245.0	[0..7]	[348..4]
gi\|56421248, gi\|... - gi\|56421248\|ref\|YP_148566.1\| hypothetical protein GK2713 [Geobacillus kaustophilus HTA426], gi\|56381...	245.0	[0..6]	[353..5]
gi\|85711706, gi\|... - gi\|85711706\|ref\|ZP_01042763.1\| succinyl-diaminopimelate desuccinylase [Idiomarina baltica OS145], gi...	244.0	[0..3]	[349..1]
gi\|37199433, gi\|... - gi\|37680684\|ref\|NP_935293.1\| succinyl-diaminopimelate desuccinylase [Vibrio vulnificus YJ016], gi\|37...	244.0	[0..3]	[350..25]
DAPE_PSEA6 - Succinyl-diaminopimelate desuccinylase OS=Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087) G...	244.0	[0..7]	[350..4]
gi\|86166268, gi\|... - gi\|87118634\|ref\|ZP_01074533.1\| succinyl-diaminopimelate desuccinylase [Marinomonas sp. MED121], gi\|8...	244.0	[0..1]	[349..1]

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Predicted Domain #1

Region A:
Residues: [1-353]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVRNMVDYE LLKKVVEAPG VSGYEFLGIR DVVIEEIKDY VDEVKVDKLG NVIAHKKGEG  60
   61 PKVMIAAHMD QIGLMVTHIE KNGFLRVAPI GGVDPKTLIA QRFKVWIDKG KFIYGVGASV 120
  121 PPHIQKPEDR KKAPDWDQIF IDIGAESKEE AEDMGVKIGT VITWDGRLER LGKHRFVSIA 180
  181 FDDRIAVYTI LEVAKQLKDA KADVYFVATV QEEVGLRGAR TSAFGIEPDY GFAIDVTIAA 240
  241 DIPGTPEHKQ VTHLGKGTAI KIMDRSVICH PTIVRWLEEL AKKHEIPYQL EILLGGGTDA 300
  301 GAIHLTKAGV PTGALSVPAR YIHSNTEVVD ERDVDATVEL MTKALENIHE LKI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	70.39794
Match:	1xfoA
Description:	Crystal Structure of an archaeal aminopeptidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidase activity	3.33046421415418	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	2.92029075689694	bayes_pls_golite062009
hydrolase activity	2.67636468634585	bayes_pls_golite062009
exopeptidase activity	1.92607656615233	bayes_pls_golite062009
catalytic activity	1.76936806579991	bayes_pls_golite062009
metallopeptidase activity	1.36622846208556	bayes_pls_golite062009
carboxypeptidase activity	1.26773013808101	bayes_pls_golite062009
metalloexopeptidase activity	0.675221914435689	bayes_pls_golite062009
metallocarboxypeptidase activity	0.406156022753981	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: